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1.
First recognized as regulators of development in worms and fruitflies, microRNAs are emerging as pivotal modulators of mammalian cardiovascular development and disease. Individual microRNAs modulate the expression of collections of messenger RNA targets that often have related functions, thereby governing complex biological processes. The wideranging functions of microRNAs in the cardiovascular system have provided new perspectives on disease mechanisms and have revealed intriguing therapeutic targets, as well as diagnostics, for a variety of cardiovascular disorders. 相似文献
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Spontaneous breaking of time-reversal symmetry in the pseudogap state of a high-Tc superconductor 总被引:1,自引:0,他引:1
Kaminski A Rosenkranz S Fretwell HM Campuzano JC Li Z Raffy H Cullen WG You H Olson CG Varma CM Höchst H 《Nature》2002,416(6881):610-613
A change in 'symmetry' is often observed when matter undergoes a phase transition-the symmetry is said to be spontaneously broken. The transition made by underdoped high-transition-temperature (high-Tc) superconductors is unusual, in that it is not a mean-field transition as seen in other superconductors. Rather, there is a region in the phase diagram above the superconducting transition temperature Tc (where phase coherence and superconductivity begin) but below a characteristic temperature T* where a 'pseudogap' appears in the spectrum of electronic excitations. It is therefore important to establish if T* is just a cross-over temperature arising from fluctuations in the order parameter that will establish superconductivity at Tc (refs 3, 4), or if it marks a phase transition where symmetry is spontaneously broken. Here we report that, for a material in the pseudogap state, left-circularly polarized photons give a different photocurrent from right-circularly polarized photons. This shows that time-reversal symmetry is spontaneously broken below T*, which therefore corresponds to a phase transition. 相似文献
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Whose larvae? 总被引:1,自引:0,他引:1
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S. H. Koslow M. Stepita-Klauco L. Olson E. Giacobini 《Cellular and molecular life sciences : CMLS》1971,27(7):799-801
Zusammenfassung Sympathische Ganglien, wenn mit Fasern desN. splenicus reinnerviert, bilden 2 pharmakologisch differente Synapsengruppen: normale, vom cholinergischen Typ und ca. 20% exitatorische vom «monoaminergischen» Typ, wenn sie von adrenergen Fasern reinnerviert wurden. 相似文献
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Serum proteins of germ-free rats fed water-soluble diets 总被引:2,自引:0,他引:2
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Song K Nam YJ Luo X Qi X Tan W Huang GN Acharya A Smith CL Tallquist MD Neilson EG Hill JA Bassel-Duby R Olson EN 《Nature》2012,485(7400):599-604