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1.
不同应变水平拉伸对成骨细胞生理功能的影响   总被引:6,自引:0,他引:6  
采用四点弯曲加载装置对大鼠颅盖骨中分离出的成骨细胞施加周期性拉伸刺激,研究成骨细胞对不同应变水平的拉伸刺激的生理响应。结果表明,500微应变的周期性拉伸刺激促进了成骨细胞的增殖,细胞的^3H-脯氨酸掺入量增加,碱性磷酸酶(ALP)活性和向胞外分泌钙均升高;而1000微应变的周期性拉伸抑制了成骨细胞的增殖、^3H-脯氨酸掺入量、碱性磷酸酶活力和向胞外分泌钙都降低,说明成骨细胞能够分辨不同变水平的力学刺激,500微应变的周期性拉伸刺激有利于细胞的生长和分化,而1000微应变的周期性拉伸对细胞的生理活性有抑制作用。而且细胞在增殖、基质合成和分化、矿化上表现出一致的变化趋势。  相似文献   

2.
拟膜分析法及应用   总被引:1,自引:0,他引:1  
将具有周期性微结构的平面网格结构比拟成均匀的连续体一拟膜,通过分析连续体的力学响应预测原网格结构的响应.根据两者在面内力学行为上的等效性,拟膜的弹性本构参数可由网格结构单胞的材料和几何参数解析表示.分析发现:当原网格结构单胞中各个杆件保持材料性质不变,而面内的几何尺寸扩大相同倍数时,拟膜的弹性本构保持不变,称这种性质为网格结构的几何内禀性.数值算例进一步证实这个结论及拟膜分析法的正确性.  相似文献   

3.
用全反维甲酸(RA)10^-7mol/L对生长在玻璃皿(G)和人工基膜上的鼻咽癌细胞株细胞进行9d的诱导分化。结果显示生长在G上的癌细胞增殖被抑制,软琼脂内集落形成和裸鼠体内生长等恶性的表型减弱,生长在ABM的细胞则不受影响,但其表面微绒毛丰富,细胞的紧密连接、交指状连接、桥粒和腺腔样结构多见,高尔基器,粗面内浆网发育较好。表明不同的培养基质对RA的生物学作用有不同的影响,ABM有拮抗RA抑制癌细  相似文献   

4.
鄂尔多斯盆地延长组绿泥石膜的形成机制   总被引:1,自引:0,他引:1  
通过包裹体、铸体薄片、带有能谱仪的扫描电镜技术对鄂尔多斯盆地延长组长8砂岩中的绿泥石膜进行分析测试,研究其形成机制和过程及其与物性的关系。研究表明:绿泥石膜具有双层膜结构,由骨架颗粒向孔隙方向依次为里层膜和外层膜;等厚的外层膜发育在压实作用之后,由孔隙水中析出的绿泥石晶体聚集在骨架颗粒表面形成,由于原生孔隙提供了充足的生长空间,致使生成的绿泥石晶粒大,晶形好,集合体有规律地排列;在外层膜的双向阻滞作用下,里层膜开始在骨架颗粒边缘溶蚀产生的小孔腔中生长,因空间狭小造成绿泥石晶体小,晶形差,集合体杂乱堆积;随成岩环境的变化,碎屑石英表面在外层膜形成后,经历了里、外层膜同时生长和停止的反复交替,而碎屑长石表面的里、外层膜则表现为此长彼停的循环过程;绿泥石膜胶结是一种破坏性成岩作用,其发育的砂岩物性好仅仅是表象,本质是物性好的砂岩有助于绿泥石膜发育。  相似文献   

5.
植入体内的生物材料与人体细胞发生作用,这种作用对细胞的生长、分裂呈明显的周期性,其周期又受到胞内胞外诸多因素的影响。一般对细胞生长、分裂的影响作为一个整体看待。HeLa细胞接种在有机玻璃(PMMA)、成都科大Ⅱ型聚氨酯、Pelethane2363-55D型聚氨酯等材料表面上生长的形态和数量等呈显著差异,而在培养基中加入阿糖胞苷抑制DNA合成后,细胞在形态上虽有差异,但数量上趋于相同。结果提示,三种材料对细胞的着床、贴壁和存活生长作用相似,而分裂周期则不同,从而导致细胞生长、分裂整体情况的不同。  相似文献   

6.
利用双层吸收膜模型,采用消光式椭圆偏振仪,对用MOCVD方法生长的(AlxGa1-x)yIn1-yP(本征)、(AlxGa1-x)yIn1-yP(掺Mg)和(AlxGa1-x)yIn1-yP(掺Si)3个样品及它们的表面氧化膜的光学参数进行了测量和计算,并对其结果加以讨论.另外还在室温下对(AlxGa1-x)yIn1-yP(本征)表面氧化膜的生长速率及其厚度进行研究,并得到膜厚与时间的线性关系曲线  相似文献   

7.
不同浓度的扶桑花醚不溶物HR-2对体外培养的人绒毛膜组织的形态、HCG和孕酮分泌的影响。观察了HR-2对小鼠离体子宫的刺激作用及不同阻断剂对子宫活动力的影响。结果表明:1)HR-2可以明显抑制人绒毛膜组织细胞的正常生长。2)培养液中的孕酮含量随HR-2的浓度增加呈梯度下降(P〈0.01);而HCG仅在高浓度时有明显降低.3)HR-2对离体的小鼠子宫有直接的兴奋作用(P〈0.01),这种兴奋作用不被  相似文献   

8.
以玉米离体根和根细胞质膜(PM)为材料,研究了加铁培养和缺铁条件下EDTA-Fe^3+还原酶和硝酸还原酶(NR)各自的活性差异,并比较了加入EDTA-Fe^3+和铁氰化物对缺铁和加铁培养的根细胞质膜上NR活性的影响。发现缺铁条件下根细胞PMEDTA-Fe^3+还原酶活性比对照高约15-23%,NR活性比对对照下降17-43%,离体根实验也证明缺陷铁条件下EDTA-Fe^3+还原酶活性高于加铁培养,  相似文献   

9.
(AlxGa1—x)yIn1—yP表面氧化特性   总被引:1,自引:0,他引:1  
利用双层吸收膜模型,采用消光式椭圆偏振仪,对用MOCVD方法生长的(AlxGa1-x)yIn1-yP(本征)、(AlxGa1-x)yIn1-yP(掺Mg)和(AlxGa1-x)yIn1-yP(掺Si)3个样品及它们的表面氧化膜的光学参数进行了测量和计算,并对其结果加以讨论。另外还在室温下对(AlxHa1-x)yIn1-yP(本征)表面氧化膜的生长速率及其厚度进行研究,并得对膜厚与时间的线性关系曲线  相似文献   

10.
核型多角体病毒是重要的杆状病毒,在其生活周期中存在有包涵体产生的病毒粒子和出芽病毒粒子两种形式的子代病毒.出芽病毒能有效地感染血腔细胞,并且发现,它的感染能力决定于病毒粒子囊膜上的gp67蛋白,gp67蛋白为酸激发的膜融合作用所必需.gp67蛋白还是囊膜上唯一由病毒编码的膜蛋白.序列分析表明,gp67蛋白与木瓜蛋白酶同源,蛋白分子的主要功能区有N端的信号肽序列,C端的转膜固着序列,以及中间的外作用区域,膜融合作用区段位于外作用区域上.gp67蛋白在胞质合成后,会发生寡聚化及糖基化其他.gp67基因的转录存在有依赖于TATA盒和不依赖于TATA盒两种转录因子,并且这两种方式有部分重叠现象.利用gp67蛋白的基因工程正引起人们的重视  相似文献   

11.
Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.  相似文献   

12.
何延凌 《科技信息》2008,(4):258-258
Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women's language from these perspectives: pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women's language, more attention should be paid to language use in social context. What's more, the linguistic phenomena in a speaking community can be understood more thoroughly.  相似文献   

13.
理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。  相似文献   

14.
As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.  相似文献   

15.
正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-  相似文献   

16.
We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-  相似文献   

17.
正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that  相似文献   

18.
For molecular systems,the quantum-mechanical treatment of their responses to static electromagnetic fields usually employs a scalar-potential treatment of the electric field and a vector-potential treatment of the magnetic field.Although the potential for each field separately is associated with the choice of an(unphysical)origin,the precise choice of the origin for the electrostatic field has little consequences for the results.This is different for the  相似文献   

19.
<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with  相似文献   

20.
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