1—（3—吡啶甲酰基）—4—芳酰基硫脲类化合物的合成

报道了1－（3－吡啶甲酰基）－4－芳酰氨基硫脲类化合物的合成及鉴定。以烟酸和取代苯甲酸为起始原料,合成了一系列分子中含吡啶基团的芳酰氨基硫脲,经元素分析,IR光谱,^1H NMR谱和MS谱分析,确定了这类化合物的结构。     

α-(1H-1,2,4-三唑-1-基)-β-芳胺基丙烯腈的合成及生物活性

利用芳胺与中间体α－（1H－1，2，4-三唑－1－基）－β－芳胺基丙烯腈腈盐酸盐（2）的亲核取代反应，合成了一系列目标化合物α－（1H－1，2，4-三唑－1－基）－β－芳胺基丙烯腈（3a-3r)，所有化合物均经元素分析和^1H NMR确定，由^1H NMR分析结果推断为E式构型，初步生物活性测定结果表明，部分化合物有一定的杀菌活性。     

N，N′—对苯二胺基—二苄基—α—氨基—1，3，2—二氧磷杂环膦酸酯的合成及表征

由芳香醛，异丁醛，三氯化磷和乙醇为原料制得中间体5，5－二甲基－1，3，2－二氧磷杂环乙烷－2－氧（DPDO），用DPDO与由芳醛和对苯二胺缩合制得的席夫碱（SB）经Pudovik加成反应，合成了系列膨胀型阻燃剂N，N′－对苯二胺基－二苄基－α－氨基－1，3，2－二氧磷杂环磷酸酯（A1－A12），并用IR，NMR，MS等对化合物进行了表征。     

利用氧化反应合成3—羟基—4—芳基—5—（1—苯基—5—甲基—1，2，3—三唑—4—基）—1，2，4—三唑衍生物的新方法

采用不同的氧化剂对ω[5-（1－苯基－5－甲基－1,2,3－三唑－4－基）－4－芳基－1,2,4－三唑－3－硫基]－ω－（1H－1,2,4－三唑－1－基）苯乙酮进行了氧化,结果发现KMnO4作为氧化剂时,氧化产物十分复杂,难于分离,而H2O2－AcOH及间氯过氧苯甲酸（MCPBA）又不能将其氧化,最后采用NaIO4作为氧化剂时没有得到相应的砜或亚砜而意外得到3－羟基－4－芳基－5－（1－苯基－5－甲基－1,2,3－三唑－4－基）－1,2,4－三唑衍生物,化合物的结构经元素分析和波谱确证,并对其生成机理作了初步讨论。     

含β-D-糖苷的5-氟尿嘧啶类抗肿瘤药物的合成

以糖为原料,经过乙酰化、溴化得到溴代糖．以所得的溴代糖与5-氟尿嘧啶-1-基-乙酸及N^1-(2-呋喃烷基)-5-氟尿嘧啶通过酯化、N-烷基化反应,合成了8个新型含糖苷的5-氟尿嘧啶类衍生物,采用IR、MS和^1H NMR表征了目标化合物的结构．     

溴素的有机化学——Ⅶ.2，2—双（溴甲基）—1，3—丙二醇和多溴代酚的环状

由2，2－双（羟甲基）－1，3－丙二醇开始，经溴ZA人，磷酰氯化，和酰基化等步骤，合成三种新的2，2－双（溴甲基）－1，3－丙二醇和多溴代酚的环状磷酸酯，即：5，5－双（溴甲基）－1，3－二氧－2－磷酰基－2－（2，4，6－三溴苯氧基）环乙烷；5，5－双（溴甲基）－1，3－二氧－2－磷酰基－2－（2，3，4，5，6－五溴苯氧基）环乙烷；双[5，5－双（溴甲基）－1，3－二氧－2－磷酰基]－2－（2，3，5，6－四溴苯氧基）环乙烷。通过对产物元素分析，IR和质子NMR测定，对其结构进行了鉴定。     

N-(2-甲氧基-5-甲酰基苄基)亚胺基二乙酸的合成及表征

以4－甲氧基苯甲醛为原料，在无水氯化锌催化下，用浓盐酸和40％甲醛溶液进行氯甲基化反应制得取代氯苄，再以新制的无水碳酸钾为质子吸收剂、干燥的乙腈为溶剂，与亚氨基二乙酸二乙酯进行N－烷基化反就，然后用Ba(OH)2－水悬浮液进行了水解得到N－（2－甲氧基－5－甲酰基苄基）亚胺基二乙酸的钡盐沉淀，最后用烯硫酸处理得到N－（2－甲氧基－5－甲酰基苄基）亚胺基二乙酸，该方法产率高，工艺简单，通过^1H NMR、IR和元素分析对所得化合物的结构进行了表征。     

3—（3—吡啶基）—4—氨基—5—苯胺基—1，2，4—三唑的合成

本文报道了1－3－吡啶甲酰基）－4－苯基氨基硫脲在水合肼存在下关环,合成了新化合物3－3－（吡啶基）－4－氨基－5－苯胺基苯胺基－1,2,4三唑,并用氨谱,碳谱表征了其结构。     

单－6－（咪唑－1－基）－β－环糊精的合成

由β－ＣＤ—ＯＴｓ或β－ＣＤ－Ｉ在ＤＭＦ中，和过量咪唑反应，合成了单－６－（咪唑－１－基）－β－环糊精（简称β－ＤＣ－Ｉｍ）．产率较高，分别为６０％和６２％．并对化合物的结构进行了ＴＬＣ、ＩＲ、ＵＶ、１ＨＮＭＲ及元素分析等确证．其中ＵＶ数据未见文献报道．     

3β—取代5—甾烯并—1—取代[17,16—C]吡唑啉—5—酮和3β—取代5—甾烯并[17,16—C]异恶唑啉—5—酮的合成

以3β－取代5－甾烯－17－酮与碳酸二甲酯经Claisen综合，所得产物再分别与肼或羟胺反应，设计合成了几种3β－取代5－甾烯并－1－取代[17,6-C]吡唑啉－5－酮和3β－取代5－甾烯并[17,16-C]异恶唑啉－5－酮，其结构经元素分析、IR、^1H NMR和^13C NMR确证。     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Density Functional Theory for the Response of Periodic Systems to Electric Fields Based on the Vector Potential Approach

正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that     

On the Thermodynamic Limit for Responses to Static Electromagnetic Fields

For molecular systems,the quantum-mechanical treatment of their responses to static electromagnetic fields usually employs a scalar-potential treatment of the electric field and a vector-potential treatment of the magnetic field.Although the potential for each field separately is associated with the choice of an(unphysical)origin,the precise choice of the origin for the electrostatic field has little consequences for the results.This is different for the     

An affordable accurate evaluation of the binding conformations predicted by molecular docking studies in bio-system

Franck-Condon factors bridge the gap between theoretical modeling and experimental observations for molecular electronic spectroscopy and electron transfer.Under the displaced harmonic oscillator approximation,multidimensional Franck-Condon factors are decomposed into a product of many one-dimensional(1D)Franck-Condon(FC)factors,and each 1D-FC factor is associated with one Huang-Rhys factor that determines the leading contribution of     

Call for Papers

<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with     

Journal of Donghua University ( English Edition) Contents of Volume 31

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