共查询到20条相似文献,搜索用时 15 毫秒
1.
H. Kobayashi K. Hashimoto S. Uchida J. Sakuma K. Takami M. Tohyama F. Izumi H. Yoshida 《Cellular and molecular life sciences : CMLS》1987,43(3):314-316
Summary Rat calcitonin gene related peptide (CGRP) and salmon calcitonin (CT) stimulated adenylate cyclase activity in a dose-dependent manner in the rat diaphragm and in the kidney. The ED50 value of rat CGRP was lower and that of salmon CT was higher in the diaphragm than in the kidney. These results suggest that CGRP stimulates adenylate cyclase activity in the striated muscle by reacting with sites distinct from the site in the kidney. 相似文献
2.
Adenylate cyclase activity in rat striatum decreased post mortem. Half-lives were about 2.7 h at 22 degrees C, 72 h at 4 degrees C. Differences in stability after death of adenylate cyclase in human brain and rat striatum, and possible heterogenity of the enzyme, are briefly discussed. 相似文献
3.
Summary Adenylate cyclase activity in rat striatum decreased post mortem. Half-lives were about 2.7 h at 22°C, 72 h at 4°C. Differences in stability after death of adenylate cyclase in human brain and rat striatum, and possible heterogenity of the enzyme, are briefly discussed.We thank Miss Karin Eckert for excellent technical assistance. 相似文献
4.
Summary Adenylate cyclase responses of brain cortex and neostriatum to noradrenaline and dopamine are increased in rats with jaundice in proportion to its severity. In comparing the situation with uraemia, the relevance of phenols has to be considered. 相似文献
5.
Adenylate cyclase responses of brain cortex and neostriatum to noradrenaline and dopamine are increased in rats with jaundice in proportion to its severity. In comparing the situation with uraemia, the relevance of phenols has to be considered. 相似文献
6.
R. P. Ebstein M. Steinitz J. Mintzer I. Lipshitz J. Stessman 《Cellular and molecular life sciences : CMLS》1985,41(12):1552-1554
Summary Beta-adrenergic-associated cyclic AMP accumulation was studied in intact lymphocytes before and after transformation with Epstein-Barr virus into immortal cell lines. Although a marked reduction in isoproterenol-stimulated cyclic AMP synthesis was observed in transformed cells, forskolin-stimulated cyclic AMP accumulation was preserved. A parallel loss of125-iodocyanopindolol binding sites suggests that the reduction in beta-adrenergic-stimulated AMP synthesis is due to receptor down regulation. 相似文献
7.
Beta-adrenergic-associated cyclic AMP accumulation was studied in intact lymphocytes before and after transformation with Epstein-Barr virus into immortal cell lines. Although a marked reduction in isoproterenol-stimulated cyclic AMP synthesis was observed in transformed cells, forskolin-stimulated cyclic AMP accumulation was preserved. A parallel loss of 125-iodocyanopindolol binding sites suggests that the reduction in beta-adrenergic-stimulated AMP synthesis is due to receptor down-regulation. 相似文献
8.
Summary Theophylline (0.01–10.0 mM) did not incease but rather decreased adenylate cyclase activity (AC) of guineapig auricles. Isoprenaline (1–100 M) and sodium fluoride (0.3–10.0 mM)stimulated AC in aconcentration-dependent manner.This work was supported by the Deutsche Forschungsgemeinschaft. The continous advice of Dr U. Schwabe is gratefully acknowledged. 相似文献
9.
Zusammenfassung Calcitonin als neues kalzium- und phosphor-senkendes Hormon wurde auf seine Wirkung auf die inorganische Pyrophosphataseaktivität von Knochen untersucht. Eine Steigerung der alkalinen Pyrophosphataseaktivität wurde vor der starken Senkung des Serum-Kalziums beobachtet. 相似文献
10.
11.
G Fillion J C Rousselle M Goiny P Pradelles F Dray J Jacob 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1977,285(3):265-268
A serotonine-sensitive adenylate cyclase system has been observed in horse brain membrane preparations. In crude mitochondrial fraction two types of activation sites were characterized, the Ka being = 2 nM and 1 micrometer. In purified synaptosomal membranes, a single adenylate cyclase activation was observed corresponding to the highest apparent affinity (KD = 2nM). This activation site might be related to the high affinity binding site (KD = 2NM) were previously described in the same membrane preparations. 相似文献
12.
R. Utili A. Di Donato G. Draetta G. Paolisso C. O. Abernathy G. Illiano 《Cellular and molecular life sciences : CMLS》1982,38(7):831-833
Summary
Escherichia coli endotoxin inhibited the fluoride-stimulated adenylate cyclase activity of liver plasma membranes enriched with bile canaliculi. Inhibition was of a mixed competitive and uncompetitive type. This effect, which may result from changes of membrane organization, may have relevance in the understanding of endotoxin-cell membrane interactions. 相似文献
13.
14.
Tendon shortening in the digastric muscle of the rabbit resulted in a short term increase in gross muscle length and sarcomere length. Subsequently, muscle and sarcomere lengths decreased to less than control values. Long-term measurements suggested that a return to control sarcomere length may have been achieved by a reduction in sarcomere number. 相似文献
15.
16.
A Smokovitis 《Experientia》1978,34(4):483-484
Histochemical study of many organs of male and female adult Wistar rats of the same age showed no difference in fibrinolytic activity (plasminogen activator activity) between the sexes. 相似文献
17.
A. Smokovitis 《Cellular and molecular life sciences : CMLS》1978,34(4):483-484
Summary Histochemical study of many organs of male and female adult Wistar rats of the same age showed no difference in fibrinolytic activity (plasminogen activator activity) between the sexes. 相似文献
18.
Isolated rat skeletal muscle mitochondria took up about 40-ng-atoms O per mg protein, with glutamine as the only respiratory substrate. The mitochondria incubated in the presence of glutamine and KCN formed both ammonia and glutamate in equivalent amounts. The experiments reported here provide suggestive evidence that rat skeletal muscle mitochondria contain glutaminase (L-glutamine amidohydrolase EC 3.5.1.2.) activity. 相似文献
19.
Summary Isolated rat skeletal muscle mitochondria took up about 40-ng-atoms O per min per mg protein, with glutamine as the only respiratory substrate. The mitochondria incubated in the presence of glutamine and KCN formed both ammonia and glutamate in equivalent amounts. The experiments reported here provide suggestive evidence that rat skeletal muscle mitochondria contain glutaminase (L-glutamine amidohydrolase EC 3.5.1.2.) activity.This work was supported by the Polish Academy of Sciences within the project II. 1, 2, 6. 相似文献
20.
D Bataille F Peillon J Besson G Rosselin 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1979,288(17):1315-1317
Receptors for the Vasoactive Intestinal Peptide (VIP) were characterized in particles enriched in plasma membranes obtained from a human prolactin-secreting pituiatry tumor. Native VIP inhibited competitively the binding of 125I-VIP to the particles and stimulated cyclic AMP production; both these effects were observed at concentrations of VIP as low as 10(-11)-10(-10) M, which are compatible with VIP concentrations in the hypothalamopituitary portal blood. 相似文献