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1.
Summary The present study deals with the dissociation of human dopamine hydroxylase (DBH) in subunits with a mol. wt of 79,500, and the preparation of specific antibodies in rabbits. No cross-reactivity was observed between human DBH and antibodies against human DBH subunits.

Nous remercions Madame M. Le Maout pour son excellente aide technique.

Ce travail a bénéficié de l'aide de l'INSERM (contrat no 75.4.161.2).  相似文献   

2.
Summary In the rat, X-irradiation leads to a decrease of the net RNA and DNA content of the spleen, without, however, increasing the low molecular weight nucleic acid derivatives in the acid-soluble fractions of the same tissue. It is suggested that an alteration of the cell membranes could account for the apparent elimination of these nucleic acid degradation products which should normally appear in the acid-soluble fraction.  相似文献   

3.
Summary The concept, that viscous metamorphosis of platelets and clot retraction is initiated by thrombin and a dialyzable factor was confirmed. Under certain circumstances glucose acts as dialyzable factor. Clot retraction seems to depend upon the catabolism of glucose.  相似文献   

4.
Summary We noticed the formation of a precipitate on adding salmine to dilute aqueous protein solution at pH 6–7. Human and bovine serum albumin, human -globulin, and the perchloro- and sulfosalicylosoluble mucoides do not precipitate in this condition. - and -lipoproteins prepared by floatation and by Sandor's technique gave S-shaped nephelometric titration curves, as did haptoglobin, a mixture of the types Hp II-Hp II and Hp II-Hp I. In sera incubated 24 h at 37°C with protamin, the dextran sulphate test and the cetavlon test show a diminished value for -lipo- and -glucoprotein. Lipoprotein degradation is probably enzymatic in nature.  相似文献   

5.
Summary It is shown that certain compounds belonging to the group of angular benzophenarsazines display a high specific bacteriostatic activity towardsMicrococcus pyogenes var.aureus. This biological property provides a further ground of similarity between these compounds and one of their structural analogues, 3,4–5,6-dibenzocarbazole.  相似文献   

6.
Summary The action of various proteolytic and glucidolytic enzymes on the biological potency of Human Menopausal Gonadotropin was studied. Trypsin, chymotrypsin, papaïn and glucosidase attack the gonadotropin only after 6 h of digestion. Carboxypeptidase and RDE produce a rapid inactivation.  相似文献   

7.
Summary A series ofin vitro experiments have been made on lactic acid production in anaerobiosis in the developing optic lobes (mesencephalon) of the chick embryo. The rate of anaerobic glycolysis is relatively important during multiplication of the neuroblasts; but, during the differentiation of the neuroblasts into mature neurons, the anaerobic processes are lower than the phosphorylation and oxidation mechanisms essential for the growth of nerve expansions and onset of functional activity.  相似文献   

8.
9.
Summary Prealbumin is prepared by a new method. Its homogeneity is demonstrated and its electrophoretic behaviour is discussed. Some new physico-chemical characteristics are determined.  相似文献   

10.
Summary The serotonin (5-hydroxytryptamin) which shows a slight influence upon the growth of plant tissues, acts upon water uptake by regulating cellular permeability (latter is activated in the case of K+).  相似文献   

11.
Summary The use of tissues slices for metabolic studies gives results valuable only from the qualitative view-point. The histochemistry of liver slices reveals indeed that there is a disappearance of the basophilia of the inner layers of cells and, consequently, autoradiographic preparations of slices incubated with tagged glycine show that the incorporation of the amino-acid is limited to the outer layers of cells.  相似文献   

12.
Summary A new chromatographic technique is described, which makes use of the affinity of anhydrides and imides of tetrahalogenophthalic acids towards aromatic and heterocyclic polycyclic compounds. This method has been successfully applied to the resolution of some problems of analytical organic chemistry.  相似文献   

13.
Summary An investigation has been made of the inhibitory effects on the secretions of the anterior pituitary of four ,,-triarylethylenes with weak oestrogenic activity. These substances have been found to vary in the degree to which they inhibit each of the secretions investigated.  相似文献   

14.
Summary Quantitative determination of bacteriolysis with different T1–7-phages confirms earlier observations that with substances inhibiting the action of T1-phage the normal respiratory metabolism of the protected bacteria is quantitatively restored in every detail.With T2-phage, showing a different respiratory course of bacteriolysis, no effect is obtained with the same substance, either on the respiration of the bacteria or on the typical course of respiration during bacteriolysis. The action of the phage inhibiting substance against T1-phage is therefore an effect of definite specificity.  相似文献   

15.
Zusammenfassung In Gewebekulturen vonBombyx mori -Gonade und und vonHelix aspersa-Bindegewebe abimpfbare Fibroblasten-Zellenstämme wurden erhalten. Die Zusammensetzung der Nährflüssigkeiten ist gegeben, und es wird auf Schwierigkeiten in der Gewebekultur Wirbelloser hingewiesen.  相似文献   

16.
Summary The uptake of labelled RNA and protein precursors inVicia faba root meristems into nuclei at 4°C is less depressed than in the cytoplasm. Reversion of the normal pattern of incorporation would seem to indicate an inhibition of the RNA transfer from nucleus to cytoplasm.  相似文献   

17.
Summary A large number of N,N-diarylthioureas and N-aryl-N-pyridylthioureas have been tested forin vitro tuberculostatic activity, and several of them have been found highly active. A series of 1-acyl-4-arylthiosemicarbazides have likewise been investigated, and most of them found to be active at a concentration of 10–4; this is considered the basic activity corresponding to the molecular grouping -CO-NH-NH-CS-NH-.  相似文献   

18.
Summary A large number of sulphur-containing compounds bearing the thiourea group -NH-CS-NH-, including substituted thiocarbanilides, 1-acyl-4-arylthiosemicar-bazides, 1-(arylaminothioformyl)-thiosemicarbazides, 4-aryl-1-(arylaminothioformyl)- thiosemicarbazides, and other related substances have been tested for potential antiviral activity. Several of these compounds have been found chemotherapeutically active against influenza virus.

Communication présentée au Congrès international de Chimie pure et appliquée de Zürich (Juillet 1955).  相似文献   

19.
20.
Les Sphériques ont été écrites par Ménélaos sous la forme dun traité dapparence purement mathématique. Cependant, la matière qui y est développée dans les deuxième et troisième livres est étroitement liée à des problèmes rencontrés en astronomie: calcul des coordonnées équatoriales du Soleil, établissement de tables dascensions, étude du mouvement du Soleil dans la sphère oblique, levers simultanés. Ce lien, qui demeure implicite dans le texte, a été mis en évidence par deux mathématiciens et astronomes arabo-musulmans, qui ont exposé la signification astronomique de certains théorèmes des Sphériques. Nous présenterons, commenterons et complèterons cette explicitation en classant les théorèmes concernés en trois groupes: sens de variation de certaines grandeurs sur la sphère, propositions de trigonométrie sphérique et applications, sens de variation de rapports entre certaines grandeurs sur la sphère. The Spherics were written by Menelaos in the form of a purely mathematical treatise. However, the material developed in the second and third book is closely linked to problems met in astronomy: computation of equatorial coordinates of the Sun, setting up of rising-time tables, study of the motion of the Sun in the sphaera obliqua, simultaneous risings. This link, which remains implicit in the text, was clearly displayed by two arabo-islamic mathematicians and astronomers, who expounded the astronomical meaning of some theorems of the Spherics. We describe, comment and complement their explanations, by classifying the implications of the theorems in three groups: direction of variation of some quantities on the sphere, spherical trigonometry and applications, direction of variation of ratios of some quantities on the sphere.Presenté par M. Folkerts(Manuscrit reçu le 23 octobre 2002) Publié en ligne le 5 février 2004An erratum to this article can be found at  相似文献   

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