Roquefortine and isofumigaclavine A,metabolites fromPenicillium roqueforti

Summary The structures of two metabolites fromPenicillium roqueforti, designated roquefortine and isofumigaclavine A, have been determined by chemical and spectroscopic studies.     

Kininase and anti-inflammatory activities of acid carboxypeptidase fromPenicillium janthinellum

Summary The acid carboxypeptidase fromPenicillium janthinellum catalyzed the rapid release of arginine, and the slow release of phenylalanine, proline, serine and glycine from the carboxy-terminal of bradykinin at pH 4.15 to 4.8 Anti-inflammatory activity of the acid carboxypeptidase seems to suggest that the enzyme hydrolyzed bradykinin in vivo.     

A convenient thin layer chromatographic method for the detection of cyclochlorotine and simatoxin,toxins fromPenicillium islandicum Sopp

Summary A rapid, convenient TLC method is described for detection of cyclochlorotine, a carcinogen produced by the commonly found storage moldPenicillium islandicum Sopp. This method has also led to the isolation of a new toxic metabolite, simatoxin.Acknowledgment. This work was supported by Food and Drug Administration, Washington, D.C. (Contract No. FDA-223-74-2209).