彩超诊断乳腺肿块的临床分析

目的 探讨彩色多普勒超声乳腺肿块的诊断价值.方法 对经手术和病理证实的45例乳腺肿块的彩超结果进行分析诊断.结果 9例为恶性肿瘤,36例为良性肿瘤,其中2例误诊为恶性.结论 彩超通过观察乳腺肿瘤的二维声像图特征和彩色血流频谱对于其良恶性的诊断和鉴别诊断可提供准确的诊断依据.     

彩超诊断乳腺肿块的临床分析

目的探讨彩色多普勒超声乳腺肿块的诊断价值。方法对经手术和病理证实的45例乳腺肿块的彩超结果进行分析诊断。结果9例为恶性肿瘤，36例为良性肿瘤，其中2例误诊为恶性。结论彩超通过观察乳腺肿瘤的二维声像图特征和彩色血流频谱对于其良恶性的诊断和鉴别诊断可提供准确的诊断依据。     

彩超诊断乳腺肿块的临床分析

目的探讨彩色多普勒超声乳腺肿块的诊断价值。方法对经手术和病理证实的45例乳腺肿块的彩超结果进行分析诊断。结果9例为恶性肿瘤,36例为良性肿瘤,其中2例误诊为恶性。结论彩超通过观察乳腺肿瘤的二维声像图特征和彩色血流频谱对于其良恶性的诊断和鉴别诊断可提供准确的诊断依据。     

水体沉积物中环境雌激素对底栖动物的影响

环境污染物的生态毒理学研究是目前国内外环境科学领域中的研究热点之一,而对于水体沉积物中环境雌激素对底栖生物的影响研究不多,具有重大深入研究意义.环境雌激素(EEs)进入生物体内可通过干扰生物体自身激素的合成、分泌、转运,或产生类似生物体自身激素的作用,进而影响生物体正常的动态平衡、繁殖、生长及行为.沉积物是底栖生物的主要生活场所及食物来源,其中的(EEs)在环境条件改变时会发生迁移转化,并通过生物富集和食物链放大等进一步影响水生和陆生生物乃至人类.本文综述了几类(EEs)对底栖动物的影响,以期为今后的研究工作做指导和参考.     

红外光检查仪在乳腺病中的应用：附413例临床资料

本文介绍了红外光检查仪在乳腺病中的应用并就良性恶性乳腺包块图像鉴别与其它方法检查结果进行了对比分析。     

Generation of a functional mammary gland from a single stem cell

The existence of mammary stem cells (MaSCs) has been postulated from evidence that the mammary gland can be regenerated by transplantation of epithelial fragments in mice. Interest in MaSCs has been further stimulated by their potential role in breast tumorigenesis. However, the identity and purification of MaSCs has proved elusive owing to the lack of defined markers. We isolated discrete populations of mouse mammary cells on the basis of cell-surface markers and identified a subpopulation (Lin-CD29hiCD24+) that is highly enriched for MaSCs by transplantation. Here we show that a single cell, marked with a LacZ transgene, can reconstitute a complete mammary gland in vivo. The transplanted cell contributed to both the luminal and myoepithelial lineages and generated functional lobuloalveolar units during pregnancy. The self-renewing capacity of these cells was demonstrated by serial transplantation of clonal outgrowths. In support of a potential role for MaSCs in breast cancer, the stem-cell-enriched subpopulation was expanded in premalignant mammary tissue from MMTV-wnt-1 mice and contained a higher number of MaSCs. Our data establish that single cells within the Lin-CD29hiCD24+ population are multipotent and self-renewing, properties that define them as MaSCs.     

Expression of human erythropoietin directed by mWAP promoter in mammary gland of transgenic mice

The present work has generated transgenic mice with a hybrid gene construct consisting of genomic sequences encodinghuman erythropoietin (hEPO) and governed by regulatory sequences of mousewhey acidic protein (mWAP). The construct proved effective by transient expression in lactating animal. After introducing hybrid gene construct into single-cell embryo via pronuclear microinjection, surviving embryo are reimplanted into pseudopregnant foster mother mouse. 58 mice of 86 generation zero mice obtained were identified to be positive by PCR-Southern blot and genomic DNA Southern blot methods. The integration rate is 67%.hEPO was expressed in the milk of 16 mice of 39 mice measured byhEPO ELISA kit The expression level gets over 15 μg/mL.