Concepts, anomalies and reality: a response to Bloor and Fehér

In this article I respond to the defences of the Strong Programme put forward by David Bloor and Márta Fehér in this issue. I dispute the claim that it is attention to only limited parts of the Strong Programme framework that allows me to argue that this approach: (i) leads to weak idealism, (ii) undermines the idea that theories have varying levels of instrumental success, and (iii) challenges the theoretical claims of scientific actors. Rather, I argue that these problematic positions are entailed by the constructionist tenets at the core of the Strong Programme.     

De-anthropomorphizing energy and energy conservation: The case of Max Planck and Ernst Mach

Discussions on the relation between Mach and Planck usually focus on their famous controversy, a conflict between ‘instrumentalist’ and realist philosophies of science that revolved around the specific issue of the existence of atoms. This article approaches their relation from a different perspective, comparing their analyses of energy and energy conservation. It is argued that this reveals a number of striking similarities and differences. Both Mach and Planck agreed that the law was valid, and they sought to purge energy of its anthropomorphic elements. They did so in radically different ways, however, illustrating the differences between Mach's ‘historical’ and Planck's ‘rationalistic’ accounts of knowledge. Planck's attempt to de-anthropomorphize energy was part of his attempt to demarcate theoretical physics from other disciplines. Mach's attempt to de-anthropomorphize energy is placed in the context of fin-de-siècle Vienna. By doing so, this article also proposes a new interpretation of Mach as a philosopher, historian and sociologist of science.     

Synthesis and properties of 1-deamino-, 9-decarboxy- and 1-deamino-9-decarboxy-bradykinin

Zusammenfassung Es wird über die Synthese von 1-Deamino-bradykinin, 9-Decarboxy-bradykinin und 1-Deamino-9-decarboxy-bradykinin und über deren biologische Aktivität berichtet. Nach dem verwendeten Testsystem scheint die endständige Carboxylgruppe für die Aktivität bedeutsamer zu sein als die endständige Aminogruppe.

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See H.Schröder and K.Lübke,The Peptides (Academic Press, New York 1966), vol. 2, p. 65.

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Part of the PhD Thesis of W. D.Johnson.     

Inhibition of the fluorescence of acridine, 9-aminoacridine, and 9-amino-6-chloroacridine by human serum albumin]

Study of fluorescence quenching of acridine and some 9 amino acridines upon human serum albumin additions reveals a single protein fixation site. Characteristic values of thermodynamic functions are obtained from experiments at different temperatures.     

History of Science through Koyré's Lenses

Alexandre Koyré was one of the most prominent historians of science of the twentieth century. The standard interpretation of Koyré is that he falls squarely within the internalist camp of historians of science—that he focuses on the history of the ideas themselves, eschewing cultural and sociological interpretations regarding the influence of ideologies and institutions on the development of science. When we read what Koyré has to say about his historical studies (and most of what others have said about them), we find him embracing and championing this Platonic view of his work. Ultimately I think this interpretation of Koyré's history of science is lopsided and in need of correction. I claim, rather, that a careful reading of Koyré's work suggests that a tension exists between internal and external methodological considerations. The external considerations stem from Koyré's commitment to the unity of human thought and the influence he admits that the ‘transscientifiques’ (philosophy, metaphysics, religion) have on the development of science. I suggest in conclusion then, that if we are to put a philosophical label on his work, rather than ‘Platonist’, as has been the custom, ‘Hegelian’ makes a better fit.     

Hélène Metzger: the history of science between the study of mentalities and total history

In this article, I examine the historiographical ideas of the historian of chemistry Hélène Metzger (1886–1944) against the background of the ideas of the members of the groups and institutions in which she worked, including Alexandre Koyré, Gaston Bachelard, Abel Rey, Henri Berr and Lucien Febrve. This article is on two interdependent levels: that of particular institutions and groups in which she worked (the Centre de Synthèse, the International Committee for History of Science, the Institut d'Histoire des Sciences et Techniques (Sorbonne) and the École Pratique des Hautes Études) and that of historiographical ideas. I individuate two particular theoretical aspirations pursued by the historians in Metzger's milieu: the ideal of total history and the study of the human mind. These two objectives were seen by Metzger and many others as implicating each other. Moreover, Metzger and other historians wanted to integrate the practice of commentary of texts in the realisations of those ideals. I argue, however, that these objectives proved very difficult to realise at the same time. One tradition which stemmed out of these discussions, exemplified by Bachelard, Canguilhem and Foucault, focused on the mind and knowledge, and renounced commentary of texts and total history as it was understood by the historians of the Centre de Synthèse. The latter, however, did not really pursue the study of the mind. Moreover, historians like Metzger and Koyré who practised an attentive analysis of texts could not realise total history.     

Mathematical instrumentalism, Gödel’s theorem, and inductive evidence

Mathematical instrumentalism construes some parts of mathematics, typically the abstract ones, as an instrument for establishing statements in other parts of mathematics, typically the elementary ones. Gödel’s second incompleteness theorem seems to show that one cannot prove the consistency of all of mathematics from within elementary mathematics. It is therefore generally thought to defeat instrumentalisms that insist on a proof of the consistency of abstract mathematics from within the elementary portion. This article argues that though some versions of mathematical instrumentalism are defeated by Gödel’s theorem, not all are. By considering inductive reasons in mathematics, we show that some mathematical instrumentalisms survive the theorem.