Computer simulations and experiments: The case of the Higgs boson

Simulations have been at the center of an important literature that has debated the extent to which they count as epistemologically on a par with traditional experiments. Critics have raised doubts about simulations being genuine experiments, on the ground that simulations seem to lack a distinctive feature of traditional experiments: i.e., the ability to causally interact with a target system. In this paper, we defend the view that simulations are indeed epistemologically on a par with traditional experiments. We first identify three possible ways of understanding the causal interaction claim. We then focus on the use of simulation in the discovery of the Higgs boson to show that in this paradigmatic case, simulations satisfy all three possible readings of the causal interaction claim.     

Naturalness,the autonomy of scales,and the 125 GeV Higgs

The recent discovery of the Higgs at 125 GeV by the ATLAS and CMS experiments at the LHC has put significant pressure on a principle which has guided much theorizing in high energy physics over the last 40 years, the principle of naturalness. In this paper, I provide an explication of the conceptual foundations and physical significance of the naturalness principle. I argue that the naturalness principle is well-grounded both empirically and in the theoretical structure of effective field theories, and that it was reasonable for physicists to endorse it. Its possible failure to be realized in nature, as suggested by recent LHC data, thus represents an empirical challenge to certain foundational aspects of our understanding of QFT. In particular, I argue that its failure would undermine one class of recent proposals which claim that QFT provides us with a picture of the world as being structured into quasi-autonomous physical domains.     

General Relativity and the Standard Model: Why evidence for one does not disconfirm the other

General Relativity and the Standard Model often are touted as the most rigorously and extensively confirmed scientific hypotheses of all time. Nonetheless, these theories appear to have consequences that are inconsistent with evidence about phenomena for which, respectively, quantum effects and gravity matter. This paper suggests an explanation for why the theories are not disconfirmed by such evidence. The key to this explanation is an approach to scientific hypotheses that allows their actual content to differ from their apparent content. This approach does not appeal to ceteris-paribus qualifiers or counterfactuals or similarity relations. And it helps to explain why some highly idealized hypotheses are not treated in the way that a thoroughly refuted theory is treated but instead as hypotheses with limited domains of applicability.     

Quantum jumps,superpositions, and the continuous evolution of quantum states

The apparent dichotomy between quantum jumps on the one hand, and continuous time evolution according to wave equations on the other hand, provided a challenge to Bohr's proposal of quantum jumps in atoms. Furthermore, Schrödinger's time-dependent equation also seemed to require a modification of the explanation for the origin of line spectra due to the apparent possibility of superpositions of energy eigenstates for different energy levels. Indeed, Schrödinger himself proposed a quantum beat mechanism for the generation of discrete line spectra from superpositions of eigenstates with different energies.However, these issues between old quantum theory and Schrödinger's wave mechanics were correctly resolved only after the development and full implementation of photon quantization. The second quantized scattering matrix formalism reconciles quantum jumps with continuous time evolution through the identification of quantum jumps with transitions between different sectors of Fock space. The continuous evolution of quantum states is then recognized as a sum over continually evolving jump amplitudes between different sectors in Fock space.In today's terminology, this suggests that linear combinations of scattering matrix elements are epistemic sums over ontic states. Insights from the resolution of the dichotomy between quantum jumps and continuous time evolution therefore hold important lessons for modern research both on interpretations of quantum mechanics and on the foundations of quantum computing. They demonstrate that discussions of interpretations of quantum theory necessarily need to take into account field quantization. They also demonstrate the limitations of the role of wave equations in quantum theory, and caution us that superpositions of quantum states for the formation of qubits may be more limited than usually expected.     

Preliminary data and econometric forecasting: an application with the Bank of Italy Quarterly Model

This paper discusses the use of preliminary data in econometric forecasting. The standard practice is to ignore the distinction between preliminary and final data, the forecasts that do so here being termed naïve forecasts. It is shown that in dynamic models a multistep‐ahead naïve forecast can achieve a lower mean square error than a single‐step‐ahead one, as it is less affected by the measurement noise embedded in the preliminary observations. The minimum mean square error forecasts are obtained by optimally combining the information provided by the model and the new information contained in the preliminary data, which can be done within the state space framework as suggested in numerous papers. Here two simple, in general suboptimal, methods of combining the two sources of information are considered: modifying the forecast initial conditions by means of standard regressions and using intercept corrections. The issues are explored using Italian national accounts data and the Bank of Italy Quarterly Econometric Model. Copyright © 2006 John Wiley & Sons, Ltd.     

Localization and the interface between quantum mechanics, quantum field theory and quantum gravity II: The search of the interface between QFT and QG

The main topics of this second part of a two-part essay are some consequences of the phenomenon of vacuum polarization as the most important physical manifestation of modular localization. Besides philosophically unexpected consequences, it has led to a new constructive “outside-inwards approach” in which the pointlike fields and the compactly localized operator algebras which they generate only appear from intersecting much simpler algebras localized in noncompact wedge regions whose generators have extremely mild almost free field behavior.Another consequence of vacuum polarization presented in this essay is the localization entropy near a causal horizon which follows a logarithmically modified area law in which a dimensionless area (the area divided by the square of dR where dR is the thickness of a light-sheet) appears. There are arguments that this logarithmically modified area law corresponds to the volume law of the standard heat bath thermal behavior. We also explain the symmetry enhancing effect of holographic projections onto the causal horizon of a region and show that the resulting infinite dimensional symmetry groups contain the Bondi–Metzner–Sachs group. This essay is the second part of a partitioned longer paper.     

The epistemology of climate models and some of its implications for climate science and the philosophy of science

I bring out the limitations of four important views of what the target of useful climate model assessment is. Three of these views are drawn from philosophy. They include the views of Elisabeth Lloyd and Wendy Parker, and an application of Bayesian confirmation theory. The fourth view I criticise is based on the actual practice of climate model assessment. In bringing out the limitations of these four views, I argue that an approach to climate model assessment that neither demands too much of such assessment nor threatens to be unreliable will, in typical cases, have to aim at something other than the confirmation of claims about how the climate system actually is. This means, I suggest, that the Intergovernmental Panel on Climate Change’s (IPCC׳s) focus on establishing confidence in climate model explanations and predictions is misguided. So too, it means that standard epistemologies of science with pretensions to generality, e.g., Bayesian epistemologies, fail to illuminate the assessment of climate models. I go on to outline a view that neither demands too much nor threatens to be unreliable, a view according to which useful climate model assessment typically aims to show that certain climatic scenarios are real possibilities and, when the scenarios are determined to be real possibilities, partially to determine how remote they are.     

On the raising of antibody to the synthetic anabolic steroid trienbolone,its partial characterization and preliminary application for radioimmunoassay

Summary The development of a radioimmunoassay method for the detection of trienbolone is described. It is dependent on antibody raised against a bovine serum albumin conjugate of trienbolone 17-hemisuccinate in sheep.Acknowledgment. Dr R. J. Heitzman (A.R.C., Compton) and Roussel/Uclaf (Romainville) are thanked for gifts of materials.     

The stage-dependent resistance of the chorion to external chemical damage and its relationship to embryonic diapause in the annual fish,Nothobranchius guentheri

Summary The resistance of the embryonic chorion of the annual fishNothobranchius guentheri to chemical damage in vivo was investigated by the exposure of the embryos to protease. Embryos at stages 20, 33, and 43 were the most resistant to enzymatic action. These stages of development correspond respectively to the stages at which diapause I, diapause II, and delayed hatching may occur. The magnitude of the resistance was further enhanced when diapause was induced prior to the treatment.     

The stage-dependent resistance of the chorion to external chemical damage and its relationship to embryonic diapause in the annual fish, Nothobranchius guentheri

The resistance of the embryonic chorion of the annual fish Nothobranchius guentheri to chemical damage in vivo was investigated by the exposure of the embryos to protease. Embryos at stages 20, 33, and 43 were the most resistant to enzymatic action. These stages of development correspond respectively to the stages at which diapause I, diapause II, and 'delayed hatching' may occur. The magnitude of the resistance was further enhanced when diapause was induced prior to the treatment.     

科技进步对经济增长的贡献：测定模型、认识偏差及应用研究建议

本文在对多种科技进步测定模型分析的基础上,指出我国目前对科技进步测定中存在一些偏差,并针对上述种种偏差提出了相关的应用研究建议.     

The starvation-survival state of microorganisms in nature and its relationship to the bioavailable energy

Summary Although one can measure the organic matter in various ecosystems in terms of organic carbon, this measurement does not indicate what portion of the organic carbon is bioavailable to the microorganisms. Most organic matter is recalcitrant and, therefore, most microorganisms do not have sufficient energy to carry on their metabolism for growth and reproduction. As a result, many species of bacteria will form ultramicrocells and enter a physiological state known as starvation-survival. This physiological state results in metabolic arrest which permits the organisms to survive for long periods of time without sufficient energy for growth and reproduction.Technical paper No. 8920, Oregon Agricultural Experiment Station.     

The use of canonical correlation analysis to identify the order of multivariate ARMA models: simulation and application

This paper is concerned with how canonical correlation can be used to identify the structure of a linear multivariate time series model. We describe briefly methods that use the canonical correlation technique and present simulation results in order to compare and evaluate the performance of these methods. The methods are also applied to a well‐known multivariate time series. Copyright © 2000 John Wiley & Sons, Ltd.     

The enhanced induction of metallothionein by zinc,its half-life in the marine fishPleuronectes platessa,and the influence of stress factors on metallothionein levels

Summary Intraperitoneal injection of zinc raised levels of a hepatic metallothionein-like species. Assuming that this species was metallothionein (MT) then levels were raised from approximately 20 g/g to 300 g/g in 7 days, and levels thereafter remained high for the next 4 weeks. The half-lives of the protein in liver and kidney from starved fish, measured using in vivo incorporation of³⁵S cysteine at 11°C, were approximately 27 days and 32 days respectively. The following agents failed to stimulate synthesis of MT in plaice: stress (due to catching), endotoxin, dexamethasone, cortisol and turpentine.