Effect of propolis on vestibular compensation following unilateral labyrinthectomy in rats

Unilateral labyrinthectomy (UL) results in the vestibular syndrome including nausea, vomiting, vertigo, spontaneous nystagmus (SN) and postural disturbance which abate over time in a process of behavioral recovery known as vestibular compensation. In order to investigate the effect of propolis on bestibular compensation, SN and expression of c-Fos protein in the medial vestibular nucleus (MVN) were measured in unilateral labyrinthectomized Sprague-Dawley rats with pretreatment of propolis.     

早孕小鼠子宫内膜组织中IASPP表达对胚胎着床的作用

目的:探讨早孕小鼠子宫内膜组织中P53凋亡刺激蛋白抑制因子(IASPP)的表达对胚胎着床的作用.方法:对NIH雌鼠进行阴道涂片以确定其动情周期,采用实时荧光定量PCR、Western blot以及免疫组化等分别在分子和蛋白水平上检测雌鼠子宫内膜上IASPP的表达情况;对实验组小鼠左侧子宫角注射IASPP抑制剂,最后测量...     

卵巢切除术对大鼠子宫内膜异位症的影响

目的：利用大鼠子宫内膜异位症动物模型,观察卵巢切除术对大鼠子宫内膜异位症的影响。方法：47只大鼠在建模后3周,第2次剖腹,观察移植物的生长情况和体积。将已成模大鼠随机分为两组：对照组（n＝23）和卵巢切除术组（n＝24）,对卵巢切除术组大鼠行双侧卵巢切除,分别观察两组动物成模后2、4、6和8周移植物的生长情况和体积。结果：与建模后3周时相比,成模后2、4、6和8周对照组大鼠移植物的生长情况和体积基本保持一致,而卵巢切除术组大鼠异位子宫内膜出现萎缩退化并且体积明显缩小,术后4、6和8周与术后2周相比,作用更明显,百术后4、6和8周之间无明显差异,术后8周仍可见异位内膜组织存在。组织学检查,对照组大鼠异位子宫内膜呈增生状态,而卵巢切除术组呈萎缩状态。结论：卵巢切除术可使子宫内膜异位症大鼠异位子宫内膜逐渐萎缩退化,但未能使其消失。     

Effect of lanthanum ion implantation on oxidation behavior of zircaloy

In order to investigate the effect of lanthanum ion imprantation on the oxidation behavior of zircaloy at 500℃, Zircaloy specimens were implanted by lanthanum ions with a dose range from 5×1016 to 2×1017 ions/cm2 at room temperature, and then oxidized at 500℃ for 100 min. The valence of the oxides in the scale was analyzed by X-ray Photoelectron Spectroscopy (XPS). The phase structures of the oxides in the scale were examined by Glancing Angle X-ray Diffraction (GAXRD). With the increase of implanted lanthanum ions dose, the phase structures in the oxide scale are transformed from monoclinic zirconia to hexagonal one and then to monoclinic one again. The measurement of weight gain showed that a similar change from the decreased gain to increased one again is achieved in the oxidation behavior of lanthanum ion implanted zircaloy compared with that of as-received zircaloy.     

淫羊藿甙对小鼠同种异基因皮片移植的影响

目的:研究淫羊藿甙(ICA)对小鼠同种异基因皮片移植的影响.方法:试验分为腹腔注射生理盐水、ICA、环孢素A(CsA)以及CsA与ICA联用4组,5 d后将C57BL/C小鼠的背部皮片移植到BALB/c小鼠的相同位置,用眼科缝合线缝合,观察皮片愈合情况并记录皮片外观性状、排斥时间,于第11天取移植皮片做病理石蜡切片,取淋巴结细胞和脾细胞做增殖实验(CFDA-SE染色).结果:CsA+ICA联用能够延长皮片排斥时间,使皮片愈合得更好,胸腺和脾脏指数均比单独CsA组高,切片显示浸润的炎症细胞也较少,其淋巴结细胞增殖能力明显降低.结论:CsA与ICA联合能抑制移植造成的免疫排斥反应,可能是通过抑制受体小鼠的反应性T细胞的活化增殖来降低细胞免疫反应.     

注氢诱发ODS铁素体钢中第二相分解

采用室温离子注入和低压电镜原位观察的方法,研究了注氢对国产ODS铁素体钢微观结构的影响.结果表明:原始未注氢ODS铁素体钢中存在有一定数量的(Fe,Cr)2O3,室温注氢后,(Fe,Cr)2O3无明显改变;但将其加热至450℃,(Fe,Cr)2O3即开始分解;到550℃时,部分(Fe,Cr)2O3消失,残余(Fe,Cr)2O3的成分也发生了改变.与此相反,原始未注氢ODS铁素体钢的微观结构在加热过程中却没有明显改变,(Fe,Cr)2O3并不分解.     

bFGF和NGF对小鼠免疫细胞功能的影响

目的：探讨碱性成纤维细胞生长因子(bFGF)和神经生长因子(NGF)对免疫功能的影响。方法：通过小鼠巨噬细胞吞噬。溶血空斑形成细胞(PFC)和脾细胞增殖等实验,观察bFGF和NGF对正常小鼠免疫细胞功能的影响。结果：一定剂量的啪F、NGF对小鼠免疫细胞功能有较明显的促进作用,且表现具有协同促进效应,而同剂量的NGF对免疫功能的促进作用略强于bFGF。此外,bFGF、NGF还能协同促进活化淋巴细胞分泌sIL-2R。结论：一定剂量的bFGF、NGF表现出较明显的免疫促进作用,并存在协同效应。     

唇裂修复对单侧完全唇腭裂患者上颌形态的影响

目的：观察单侧完全性唇腭裂的唇裂对上颌形态的影响，并探讨发生机理。方法：通过Ｘ线头影测量１０例成人单侧唇腭裂患者，其童年时期单纯唇裂修复而未行腭裂修复、１５例成人单侧唇腭裂患者接受过唇腭裂修复术，１０例具有正常颌关系且无唇腭裂异常的成人的头颅侧。结果：评价表明，组１、组２与组３对照，上颌有显著性后缩；比较组１、组２无显著性差异，上颌后缩未因腭裂修复出现量的加。结论：唇裂修复术后会出现上颌后缩的生长