共查询到20条相似文献,搜索用时 15 毫秒
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MOSKOWITZ M 《Nature》1955,175(4457):595-596
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Binding of noradrenaline to smooth muscle cells in the spleen 总被引:4,自引:0,他引:4
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Allograft survival prolonged by heterologous spleen cells in 'Millipore' diffusion chambers 总被引:2,自引:0,他引:2
H F Jeejeebhoy 《Nature》1967,215(5097):158-159
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Reactivation of immunocompetence in spleen cells of aged mice 总被引:3,自引:0,他引:3
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Induction of formation of presynaptic terminals in neuroblastoma cells by synapsin IIb 总被引:14,自引:0,他引:14
The synapsins are a family of closely related phosphoproteins (termed synapsins Ia, Ib, IIa and IIb) associated with synaptic vesicles and implicated in the short-term regulation of neurotransmitter release from nerve endings. During development, expression of the synapsins correlates temporally with synapse formation, but there has been no direct evidence that they are involved in synaptogenesis. Here we report that overexpression of synapsin IIb in the neuroblastoma x glioma hybrid clonal cell line NG108-15 leads, during cell differentiation, to marked increases in the number of neuritic varicosities and in the numbers of small clear vesicles and large dense core vesicles per varicosity, as well as to the appearance of synapse-like cell-cell contacts. Thus, synapsin IIb may be involved in the regulation of synapse formation and, as a result, in long-term neuronal signalling. 相似文献
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