Changing potency by spontaneous fusion

Recent reports have suggested that mammalian stem cells residing in one tissue may have the capacity to produce differentiated cell types for other tissues and organs 1-9. Here we define a mechanism by which progenitor cells of the central nervous system can give rise to non-neural derivatives. Cells taken from mouse brain were co-cultured with pluripotent embryonic stem cells. Following selection for a transgenic marker carried only by the brain cells, undifferentiated stem cells are recovered in which the brain cell genome has undergone epigenetic reprogramming. However, these cells also carry a transgenic marker and chromosomes derived from the embryonic stem cells. Therefore the altered phenotype does not arise by direct conversion of brain to embryonic stem cell but rather through spontaneous generation of hybrid cells. The tetraploid hybrids exhibit full pluripotent character, including multilineage contribution to chimaeras. We propose that transdetermination consequent to cell fusion 10 could underlie many observations otherwise attributed to an intrinsic plasticity of tissue stem cells 9.     

幂等矩阵与另一矩阵的组合的k-幂等性

研究了一个幂等矩阵P和另一个与P可交换的矩阵Q的组合aP＋bQ＋cPQ的k一幂等性。给出了当aP＋bQ＋护Q是k-幂等时，Q的分类。利用这个分类给出了两个可交换的幂等阵P、Q的组合护＋bQ＋ceQ是幂等阵和3-幂等阵的充要条件。这个结果推广了Benitez J，Thome N在2006年的结论。     

准确测定发酵液中抗生素效价新方法的研究

基于微生物对药物反应过程的动力学分析提出了一个以抑茵圈半径微分变化率为反应标准的方法．测定结果可用Gaussian分布方程得到很好的拟合．其结果受药物浓度范围影响很少，从而能得到确定的半数杀菌效价（EC50）．     

Analysis for the dorsalization potency of the animal blastomeres of the 16 cell stageXenopus embryo

The dorso-ventral axis ofXenopus embryo is established after fertilization. Blastula stage blastomeres acquire different identities as they have inherited different maternal materials which distribute radial symmetrically along the animal vegetal aixs in the full-grown oocyte, and are rearranged by the cortical rotation triggered by fertilization. The vegetal blastmeres demonstrate the different dorsalization potencies in the previous transplantation experiments. The data of blastomere explanting and RT-PCR analyzing indicate that the dorsal ventral bias also exists among the animal blastomeres even during the early blastula stage.     

混凝脱硫与A/O组合技术处理高浓度制药废水的研究

某制药厂废水含有生物抑制性较高的SO42-,SO42-在厌氧环境下与硫酸盐还原菌作用产生硫化氢,影响了微生物处理有机物的效果。采用混凝脱硫与A/O组合技术处理高浓度制药废水,使CODCr去除率高达99.35%,SO42-去除率为84.9%,提高了处理效率,出水水质可达标排放。     

家兔模拟直肠癌手术损伤盆腔植物性神经后的性机能观察

为了验证损伤盆腔植物性神经后会导致术后性机能障碍，以及进一步了解神经的走行和解剖关系，对雄性家兔进行了模拟直肠癌根治性手术的实验：即损伤其低前神经盆内脏神经及盆丛后再与雌性家兔配对，继续喂养６个月，看有无生育能力，以观察性机能。观察结果：生育者只占１０％，而对照组全部有生育，这与临床上直肠癌振治性手术后所发生的排尿、性机能障碍基本一致。这项研究为实施保存植物性神经的直肠癌手术提供了可靠依据；对维持直肠癌术后的排尿和性机能，提高生存质量有重要意义。