荧光氧传感纳米粒子的制备

采用模板法将氧敏感的荧光探针-三(2-苯基吡啶)合铱(Ⅲ)[Ir(ppy)3)]包埋在二氧化硅纳米粒子中,并将制得的二氧化硅纳米粒子(SiNP)用于氧的荧光传感检测.实验结果表明所制得的SiNP对氧的浓度响应范围在0～30. 31μg/mL.     

基于氧猝灭原理的淡水BOD微生物传感器

本研究使用溶胶-凝胶法固定二高氯酸4,7-二苯基-1,10-邻菲咯啉钌[Ru(dpp)3(ClO4)2]作为氧敏感材料,采用溶胶-凝胶杂化聚乙烯醇(PVA)法包埋枯草芽孢杆菌和地衣芽孢杆菌制得测量淡水样品的BOD微生物传感膜.在此基础上,考察了传感膜的响应时间、线性、稳定性以及温度、pH的影响,结果表明制得的BOD微生物传感器在2～30 mg/L范围内具有良好的线性和重现性.实验还初步尝试使用自制的BOD微生物传感器对地表水样品BOD进行检测.     

光纤氧传感器技术进展

综述了近年来国内外光纤氧传感器技术的研究及应用情况 ,探索了荧光指示剂的进展 ,阐述了氧传感技术和制作氧传感膜的机理及光纤氧传感器的应用情况 ,并展望了光纤氧传感器的发展趋势     

基于探针内嵌超分子囊泡的半胱氨酸荧光传感

针对高结构相似度同系物中特定化合物的检测分析流程复杂的问题,采用模块化组装的策略制备了一类嵌含光学分子探针的超分子囊泡,并在此基础上建立了一种集分离与检测功能于一体的新型荧光传感模式.将生物硫醇的广普性探针四氟对苯二甲腈嵌入由四(戊硫代)四硫富瓦烯与十二烷基-β-D-麦芽糖苷构成的超分子囊泡膜层后,囊泡对半胱氨酸展现出高选择性、宽动态范围的荧光响应,实现了半胱氨酸的便捷、灵敏检测.由四烃基四硫富瓦烯和表面活性剂共组装形成的空白囊泡制备简单,光谱可见光区背景吸收低,可作为构建此类荧光传感体系的通用模板,为这种新型传感模式的推广提供有力的支撑.     

一种新型的光驱动变构荧光分子探针

变构效应是生命体实现复杂生理效应的精妙调控和准确表达的重要途径.本研究利用双硫键的光致翻转特性,以双硫键为变构"枢纽"单元,设计、合成了一种具有非线性响应的光驱动变构荧光分子探针.合成的分子探针DSSB经过光照后,因双硫键翻转而形成刚性的分子内氢键网络,探针溶液的荧光显著增强;同时,由于阴离子的氢键活性,F-、AcO-和H2PO4-等阴离子的存在将促使氢键网络重组而呈现出不同的荧光响应.因此,该探针可实现对3种阴离子的分辨性荧光传感,并具有非线性响应的特性.     

低温固态电解质乙烯催化传感技术研究

以高聚物Ｎａｆｉｏｎ膜为固态电解质,利用混合压膜法制作传感催化电极,研制了低温固态电解质乙烯催化传感器。以氧为参比气体,Ｐｄ黑为电极催化材料,考察了Ｎａｆｉｏｎ膜含水量、不同粘合剂、电极片中Ｔｅｆｌｏｎ含量,以及温度对乙烯传感性能的影响,得出了较佳的膜电极制作工艺参数;以空气为参比气体,对乙烯传感也进行了一定探讨。     

肿瘤乏氧分子探针的研究进展

近年来,恶性肿瘤严重威胁大众生命健康,给我国社会和医疗带来了沉重的负担,其中乏氧已成为大多数实体瘤的关键特征之一,肿瘤乏氧的发展与其侵袭性和耐药性密切相关,研究其发生发展规律,对恶性肿瘤的早期诊断与筛查具有十分重要的意义。分子探针能对乏氧进行可视化检测,有望实现乏氧肿瘤的准确影像,已成为当前恶性肿瘤诊治的交叉学科前沿之一。本文基于不同生物标志物[硝基还原酶(Nitroreductase, NTR)、偶氮还原酶和氢醌还原酶(Quinone Oxidoreductase, hNQO1)]系统总结了国内外肿瘤乏氧分子探针的研究进展,重点讨论了乏氧分子探针的设计方法、检测机理、传感性能和生物应用,并对肿瘤乏氧分子探针的未来发展趋势进行了展望。     

基于平面光极的DO二维实时监测系统在生物扰动存在下水/沉积物体系中的应用

采用改进的平面传感膜制备方法, 建立应用于淡水/沉积物模拟体系的溶解氧(DO)二维分布监测系统. 结果表明： 采用物理包埋法将荧光指示剂三(4,7-联苯-1,10-邻菲啰啉)二氯化钌固定于乙基纤维素膜上, 制备的DO平面传感膜荧光强度随DO质量浓度的增加而减小, 符合荧光淬灭的Stern Volmer方程, 具有DO响应范围宽（0～20 mg/L）、 响应速度快（<60 s）、 准确性高、 可逆性和稳定性好等优点; 在生物扰动存在下, 沉积物DO变化较小, 对上覆水DO影响较大, 这是由于物理混合和氧化还原等多种机制综合作用所致, 生物扰动将直接或间接影响这些作用.     

聚硅氧烷基荧光材料

聚硅氧烷基荧光材料作为一类性能独特的有机硅材料,在荧光探针、生物传感、力学传感、发光二极管等领域具有广阔的应用前景.基于近十几年来国内外聚硅氧烷基荧光材料的相关报道,文中结合本课题组的研究成果,综述了线型、超支化和交联3类结构的聚硅氧烷基荧光材料的研究进展,总结了各类荧光材料的合成、应用及发光机理,探讨了聚硅氧烷在荧光...     

光学免疫分析仪传感芯片表面修饰及表征

光学免疫分析仪能够实现对环境污染物的现场快速检测,为了减小传感芯片对蛋白的非特异性吸附并实现对抗体的特异性反应,需要对其进行化学修饰。该文选取2,4-二氯苯氧乙酸(2,4-D)为目标物质,研究了3种传感芯片修饰方案,并对修饰后芯片表面的物理形态、化学组成及其对蛋白的响应进行了表征。实验结果表明,3种方案均有效地抑制了蛋白的非特异性吸附,且成功地实现了对2,4-D小分子配基的固定,其中双氨基聚乙二醇修饰的芯片基本不会吸附杂蛋白,而氨基葡聚糖修饰的芯片对2,4-D抗体具有更强的响应。因此,这3种修饰方案都适用于光学免疫分析仪传感芯片的制备。     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Density Functional Theory for the Response of Periodic Systems to Electric Fields Based on the Vector Potential Approach

正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that     

On the Thermodynamic Limit for Responses to Static Electromagnetic Fields

For molecular systems,the quantum-mechanical treatment of their responses to static electromagnetic fields usually employs a scalar-potential treatment of the electric field and a vector-potential treatment of the magnetic field.Although the potential for each field separately is associated with the choice of an(unphysical)origin,the precise choice of the origin for the electrostatic field has little consequences for the results.This is different for the     

An affordable accurate evaluation of the binding conformations predicted by molecular docking studies in bio-system

Franck-Condon factors bridge the gap between theoretical modeling and experimental observations for molecular electronic spectroscopy and electron transfer.Under the displaced harmonic oscillator approximation,multidimensional Franck-Condon factors are decomposed into a product of many one-dimensional(1D)Franck-Condon(FC)factors,and each 1D-FC factor is associated with one Huang-Rhys factor that determines the leading contribution of     

Call for Papers

<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with