胰岛移植治疗糖尿病的进展探究

糖尿病是一组常见的以血浆葡萄糖水平增高为特征的代谢内分泌疾病,胰岛素治疗几乎是所有类型糖尿病控制血糖的重要手段。但长期使用外源性胰岛素会产生诸如失明、肾衰、肥胖等并发症,而胰岛移植被认为是较为理想的治疗糖尿病的方法,其手术简单、安全并发症少,可纠正糖代谢紊乱,尤为重要的是它可以防止、减缓甚至逆转糖尿病性微血管病变,减少心、肾等脏器并发症的发生,降低死亡率。     

2型糖尿病胰岛素抵抗研究进展

胰岛素抵抗和B细胞功能障碍是2型糖尿病发病机制的两个主要环节,而胰岛素抵抗是2型糖尿病发生的始动因素.研究发现,信号蛋白异常和炎症因子与胰岛素抵抗的发生密切相关,探讨其相关关系为治疗糖尿病、防治或延缓其并发症的发生提供重要的科学依据.     

初诊糖尿病患者心理性胰岛素抵抗及应对措施

糖尿病易导致严重的慢性并发症,易使全身众多器官受损,严重影响患者的生活质量及寿限,早期应用胰岛素是对初诊糖尿病患者血糖得到良好控制,减少并发症的有效手段.本文将探讨如何克服胰岛素治疗初诊糖尿病患者心理障碍.     

胰岛素泵:糖尿病患者的福音

糖尿病患者的长期高血糖得不到有效控制会造成多个系统的并发症，而目前对这些并发症尚无有效治疗手段。历时十年的大规模前瞻性研究DCCT结果表明，通过胰岛素强化治疗有效控制血糖，是预防和延缓糖尿病多种慢性并发症的有效手段。随着对糖尿病的认识日趋深入和完善，越来越多的糖尿病专家呼吁“胰岛素不应再被认为只是1型糖     

糖尿病患者应用胰岛素治疗的临床观察与护理

糖尿病为慢性终生性疾病,其发病率呈逐年上升趋势,而且患者由于长期血糖控制不良,导致多系统并发症或过早死亡,生命质量与生活质量受到严重影响,应用胰岛素是治疗糖尿病或抢救糖尿病并发症的最有效的方法,现将临床应用胰岛素的护理体会报告如下。     

浅谈糖尿病的治疗与预防

糖尿病是由于胰岛素绝对或相对缺乏,引起糖、脂肪、蛋白质、维生素、水和电解质等一系列代谢紊乱．糖尿病的治疗一是合理应用口服降糖药;二是重视心理社会因素的影响,预防糖尿病的发生,不但要加强自我保健意识,而且要注意糖尿病并发症．     

胰岛素泵:糖尿病患者的福音

糖尿病患者的长期高血糖得不到有效控制会造成多个系统的并发症,而目前对这些并发症尚无有效治疗手段.历时十年的大规模前瞻性研究DCCT结果表明,通过胰岛素强化治疗有效控制血糖,是预防和延缓糖尿病多种慢性并发症的有效手段.……     

糖尿病人的饮食治疗

糖尿病是一种常见的内分泌—代谢病 ,也是影响全身各系统至心理健康的世界第三大非传染性疾病。据 1996年全国流行病学调查 ,发病率为 3.2 1% ,并呈急剧增加趋势。该病作为终身疾患需要终身治疗 ,而合理的饮食治疗是糖尿病病人康复和预防并发症的重要措施之一 ,是一种非药物干预方法。本文仅就糖尿病人的饮食治疗措施综述如下 :一、何谓糖尿病及其病因糖尿病是以持续高血糖为其基本生化特征的一种综合病症。各种原因造成胰岛素供应不足或胰岛素在靶细胞不能发挥正常生理作用 ,使体内糖、蛋白质及脂肪代谢发生紊乱 ,而引发了糖尿病。随着糖尿…     

合理应用胰岛素治疗糖尿病酮症酸中毒的探讨

介绍了使用小剂量胰岛素治疗糖尿病酮症酸中毒的临床资料及治疗效果，结果表明，同传统大剂量使用胰岛素相比，该疗法可明显减少并发症，以我，还讨论了糖尿病酮症酸中毒的发病机理。     

石河子社区2型糖尿病患者血糖控制情况三年随访研究

目的:了解石河子市社区2型糖尿病患者血糖控制情况,探讨影响血糖达标的因素。方法:采用整群抽样的方法于2012年纳入符合标准的患者300人,进行3年的随访观察,收集一般人口学信息、治疗方案及血糖相关指标等资料。根据药物治疗情况将入选对象分为口服药物治疗组、胰岛素治疗组、联合用药组。结果:2015年血糖达标率为41.2%,较2012年45.3%有所降低(P0.05)。血糖达标率均以口服药物治疗组最高,胰岛素治疗组最低;与口服药物治疗组患者相比,胰岛素治疗组和联合用药组病程长、各血糖指标(FBG、HbA1c、2hPBG)值高(P0.05)。进行logistic回归分析显示,病程、并发症是影响血糖达标危险因素,饮食控制、好的服药依从性、口服药物治疗以及自我监测血糖是其保护因素。结论:石河子社区2型糖尿病患者血糖达标率较低,饮食控制、好的服药依从性以及自我监测血糖是提高血糖达标率、延缓并发症的重要策略。     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Density Functional Theory for the Response of Periodic Systems to Electric Fields Based on the Vector Potential Approach

正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that     

On the Thermodynamic Limit for Responses to Static Electromagnetic Fields

For molecular systems,the quantum-mechanical treatment of their responses to static electromagnetic fields usually employs a scalar-potential treatment of the electric field and a vector-potential treatment of the magnetic field.Although the potential for each field separately is associated with the choice of an(unphysical)origin,the precise choice of the origin for the electrostatic field has little consequences for the results.This is different for the     

An affordable accurate evaluation of the binding conformations predicted by molecular docking studies in bio-system

Franck-Condon factors bridge the gap between theoretical modeling and experimental observations for molecular electronic spectroscopy and electron transfer.Under the displaced harmonic oscillator approximation,multidimensional Franck-Condon factors are decomposed into a product of many one-dimensional(1D)Franck-Condon(FC)factors,and each 1D-FC factor is associated with one Huang-Rhys factor that determines the leading contribution of     

Call for Papers

<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with     

Journal of Donghua University ( English Edition) Contents of Volume 31

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