我国正常人年龄与动脉血压的回归方程

本文运用统计学方法对我国正常人11-65岁年龄段的动脉血压处理，得出年龄与动脉血压的回归方程。     

急性缺血性卒中取栓术中血压参数与功能预后的相关性

目的 探讨急性前循环大血管闭塞性卒中机械取栓(MT)术中血压参数对于功能预后的影响.方法 对164例接受MT治疗的急性前循环大血管闭塞性卒中患者,依据患者治疗后90 d改良Rankin量表(mRS)分为预后良好组(0～2分,85例)和预后不良组(3～6分,79例).分析2组患者的基线资料及临床资料,术中血压参数包括基线...     

青藏高原自然环境与高原病

为了适应西部开发和青藏铁路西时,本文对青藏高原的自然地理、青藏高原气候与高原（山）病情况做了概述,以了解高原（山）病的地域流行学,掌握高原各地区的气候等特点,对高原医学研究和高原（山）病防治有指导意义,有助于高原医学的研究和学术交流。     

原发性高血压患者血压变异性与心率平均动脉压乘积的临床分析

目的:探讨原发性高血压(EH)患者24h血压变异性(BPV),心率@平均动脉压乘积(HR@MAP)的临床应用价值.方法:对48例血压正常者和88例EH患者进行动态血压监测(ABPM),对BPV、HR@MAP参数进行对比分析研究.结果:①EH组BPV和HR@MAP各项指标均显著高于正常对照组(P<0.05).②EH伴左心室肥厚劳损组BPV和HR@MAP各项指标高于EH无左心室肥厚劳损组高于血压正常组(P<0.05).结论:EH患者BPV明显高于血压正常者.EH伴左室肥大劳损组的BPV大于EH无左室肥大劳损组.EH患者的BPV越大,靶器官损害越重.     

运动训练对血压影响的相关性研究

随着高血压患者数量的增加以及患者年龄的年轻化趋势,高血压的防治已经成为一项严峻的挑战,一旦确诊患有高血压需终生治疗,现在我们对高血压的治疗主要包括降压药物治疗和非药物治疗,其中运动疗法的降压作用正日益引起重视.     

青少年体重指数与血压水平相关性的研究

目的 探讨青少年体重指数(body mass index, BMI)与血压水平的关系,为青少年预防高血压发生提供流行病学依据。方法 以2019和2020年在井冈山大学进行了新生入学体检管理的学生为研究对象(N=9061),其中男生3996人,女生5065人,分析BMI与血压水平的相关性。结果 井冈山大学2020级和2019级学生高血压检出率为4.88%,其中男生和女生检出率分别为8.61%和1.93%(x²=214.4094,P <0.001)。消瘦组、正常组、超重组、肥胖组高血压检出率分别为1.92%、3.78%、10.87%、20.44%(x²=343.879,P <0.001)。Logistic回归分析发现BMI(OR=1.169,95%CI:1.143,1.196)、谷丙转氨酶(OR=1.004, 95%CI:1.001, 1.008)、血红蛋白(OR=1.036,95%CI:1.029,1.043)是青少年高血压发生的危险因素(P <0.05)。结论 高BMI、谷丙转氨酶和血红蛋白升高是青少年高血压发生的危险因素,...     

浅谈高原病适用保外就医的几个问题

保外就医制度是我国刑事司法领域内的一项重要制度。在体现人道主义刑事政策的同时,司法实践中又存在一定的问题。尤其是针对像高原病这类特殊疾病的司法适用就更值得加以研究。本文从高原病的基本特征入手,着力寻求其在保外就医执行中所遇到的难点,在此基础上笔者提出了一定的对策和建议。以期望能起到抛砖引玉之功效。     

浅谈高原病适用保外就医的几个问题

保外就医制度是我国刑事司法领域内的一项重要制度.在体现人道主义刑事政策的同时,司法实践中又存在一定的问题.尤其是针对像高原病这类特殊疾病的司法适用就更值得加以研究.本文从高原病的基本特征入手,着力寻求其在保外就医执行中所遇到的难点,在此基础上笔者提出了一定的对策和建议.以期望能起到抛砖引玉之功效.     

浅谈高原病适用保外就医的几个问题

保外就医制度是我国刑事司法领域内的一项重要制度。在体现人道主义刑事政策的同时,司法实践中又存在一定的问题。尤其是针对像高原病这类特殊疾病的司法适用就更值得加以研究。本文从高原病的基本特征入手,着力寻求其在保外就医执行中所遇到的难点,在此基础上笔者提出了一定的对策和建议。以期望能起到抛砖引玉之功效。     

Ataxia, acute mountain sickness, and high altitude cerebral edema

Previous investigations suggest that ataxia is common and often one of the more reliable warning signs of HACE. The aim of this study was to investigate the diagnostic role of ataxia in acute mountain sickness (AMS) and high altitude cerebral edema (HACE) among mountain rescuers on the quake areas, and in approaching the relation between AMS and HACE. After the earthquake on April 14, 2010, approximately 24,080 lowland rescuers rapidly transported from sea level or lowlands to the mountainous rescue sites at 3 750m to 4 568 m, and extremely hardly worked for an emergency treatment after arrival. Assessments of acute altitude illness on the quake areas were using the Lake Louise Scoring System. Seventy-three percent of the rescuers were found to be developed AMS. The incidence of high altitude pulmonary edema (HAPE) and HACE was 0.73% and 0.26%, respectively, on the second to three day at altitude. Ataxia sign was measured by simple tests of coordination including a modified Romberg test. The clinical features of 62 patients with HACE were analyzed. It was found that the most frequent, serious neurological symptoms and signs were altered mental status (50/62, 80.6%) and truncal ataxia (47/62, 75.8 %), mental status change was rated slightly higher than ataxia, but ataxia occurred earlier than mental status change and other symptoms. The earliest sign of ataxia was a vague unsteadiness of gait, which may be present alone in association with or without AMS. Advanced ataxia was correlated with the AMS scores, but mild ataxia did not correlate with AMS scores at altitudes of 3 750-4 568 m. Of whom, 14 patients were further examined by computerized tomographic scanning of the brain and cerebral magnetic resonance imagines were examined in another 15 cases. These imaging studies indicated that the presence of the cerebral edema in 97 % of cases who clinically diagnosed as HACE (28/29). Ataxia seems a reliable sign of advanced AMS or HACE, as does altered mental status.     

Rong Shuan Jiao Nang in the treatment of acute mountain sickness and high altitude myocardial ischemic syndrome in Yushu

To evaluate the therapeutic effects of Rong Shuan Jiao Nang (RSJN) on treatment of acute mountain sickness (AMS) and high altitude myocardial ischemic syndrome in workers in Yushu,three groups were studied: group A (60 patients with AMS,given RSJN),group B (15 patients with altitude myocardial ischemic syndrome, given RSJN),and group C (control,without drugs). All studied subjects were lowland workers who were first time entry to Yushu for work at an altitude of 4 250 m. During the course of treatment,a routing physical examination was performed,AMS Lake Louise Scores were estimated,arterial oxygen saturation (SaO2),electrocardiography and hemoglobin concentration were measured before and after using RSJN for 10 days. In group A,the effective rate was 68 %,symptomatic improvement in 54 cases (90 %) within 5 days. In group B,the effective rate was 93 %,episodes of angina pectoris stopped in 12 patients within 3 ~ 7 days,one lasted 8 days. After treatment, the level of SaO2 increased 15.5 %,21.8 % and 5.6 % in group A,group B and group C,respectively. RSJN taken at the start of the arrival at Yushu can decrease AMS scores and facilitate cure. If taken after the illness has begun,RSJN may help lessen symptoms,especially effectively improved angina pectoris of the high altitude myocardial ischemic syndrome. Symptoms usually subside after 3 ~ 8 days. RSJN should be continually used for at least 7 days after ascent.     

淫羊藿对正常和应激大鼠血压的影响

采用侧脑室注射(icv)的方法,观察了淫羊藿(Herba epimedium,HE)对正常和应激性高血压(stress-induced hyportension,SIH)大鼠动脉血压的影响,并探讨了其中枢降压效果的作用机制.结果表明:常规水煮提取的淫羊藿总黄酮(TFE)对正常大鼠和应激性高血压大鼠平均动脉血压(MAP)均有降低作用,注药前后差异显著(P<0.05);而用荷包牡丹碱(bicu-culline)阻断γ-氨基丁酸A(GABAA)受体可以影响TFE的降压效应.说明侧脑室注射TFE具有降压效应,其降压机制可能与GABAA受体相关.     

三磷酸腺苷二钠对慢性高原病大鼠肝脏保护作用

 为研究三磷酸腺苷二钠对慢性高原病(chronic mountain sickness,CMS)大鼠肝脏的保护作用,取60 只SD 大鼠,对其中50 例进行慢性高原病造模后,随机分为高原模型组、硝苯地平对照组、三磷酸腺苷二钠低剂量组、三磷酸腺苷二钠中剂量组、三磷酸腺苷二钠高剂量组,每组10 只;剩余10 只平原环境饲养为正常对照组;造模30 d 后,根据大鼠体重进行干预。连续灌胃15d 后,测定肺动脉压(pulmonary artery pressure,PAP)、同型半胱氨酸(homocysteine,Hcy)、白介素-6(interleukin-6,IL-6)、C-反应蛋白(C-reactionprotein,CRP)、超氧化物歧化酶(superoxide dismutase,SOD)、丙二醛(malondialdehyde,MDA)、谷胱甘肽过氧化物酶(glutathione peroxidase,GSH-PX)、谷丙转氨酶(alanine aminotransferase,ALT)、谷草转氨酶(aspartatetransaminase,AST)等指标。结果发现,与正常对照组比较,高原模型组和硝苯地平对照组大鼠体内的Hcy,IL-6,CRP,MDA,ALT 和AST 水平升高,SOD 和GSH-PX 水平降低,PAP 升高,提示高原低氧对大鼠的肝脏造成损害。与高原模型组比较,三磷酸腺苷二钠高剂量组大鼠体内的Hcy,IL-6,CRP,MDA,ALT 和AST 水平降低(P < 0.05),SOD 和GSH-PX 水平升高(P < 0.05)。故而认为高剂量的三磷酸腺苷二钠对CMS 大鼠肝脏有保护作用。     

常压下制备乙内酰脲两种方法的比较

利用常压法制备乙内酰脲(海因)，产物收率高，纯度好，且具有很好的操作弹性。在常压下分别利用羟基乙腈、氨气和CO2，羟基乙腈和碳酸氢铵为原料，即双气法与碳铵法，分别制备出了海因，并得出了各自的最佳反应条件，其中双气法收率80．3％，碳铵法收率85.8％。双气法制备海因以往未见报道，碳铵法比以往高压制备提高了5个百分点：双气法与碳铵法成本低，收率高，均是工业化生产的好途径。     

赵岐对章句学的突破及其对"以意逆志"说的误读

赵岐的<孟子章句>打破了两汉儒者繁琐、支离的注经模式,为当时的学界注入了一股清新的学风.赵岐在章句学领域的突破得益于他对孟子的"以意逆志"法的运用."以意逆志"是孟子借已意揣摩作者思想意图的解<诗>方法,"以意逆志"说的成立依据在于孟子的"本心"说.赵岐将经验意义上的"人情"视为"以意逆志"的基础,结果误读了此说.虽然如此,赵岐还是成功地按照他所理解的"以意逆志"法解读了<孟子>一书,并由此而改写了经学的发展史.     

次高压、中压燃气压差发电实验研究

次高压、中压燃气在供给用户之前,需要经过调压装置调压,调压过程压力能损失较大,利用燃气调压过程压差发电将会有效回收这部分压力能损失。燃气压力能进行了热力学分析,燃气比由比温度和比压力组成,比压力远大于比温度。利用压缩空气模拟中压燃气,搭建了中压管道压差发电实验系统,实验研究了流量、压力比对压差发电的影响,通过实验数据拟合得到了发电功率(P)与流量(Q)、压力比(n)之间的关系式为P=16.10Qlnn。