黑白花乳牛关节滑膜炎的研究Ⅰ．两性霉素B诱发急性浆液性腕关节滑膜炎的实验研究

对７头一岁龄健康黑白花乳牛的１４个腕关节内注射两性霉素Ｂ（１２．５ｍｇ／关节），成功诱发急性浆液性腕关节滑膜炎（ＡＳＣＳ）．注射前及诱发关节炎后（注射后４８ｈ）分别抽取正常及炎性腕关节滑液（ＳＦ）样品，同时采集血液样品待检，检测结果表明：乳牛ＡＳＣＳ时，ＳＦ中细胞总数（ＴＣＣ）、总蛋白（ＴＰ）、乳酸脱氢酶（ＬＤＨ）、碱性磷酸酶（ＡＬＰ）、γ－谷氨酰转肽酶（γ－ＧＴ）、蛋白及ＬＤＨ同功酶各组分含量均显著增加（Ｐ＜０．０１）；蛋白及ＬＤＨ同功酶各组分百分含量（％）显著改变：白蛋白（Ａ）显著降低（Ｐ＜０．０１），α、β、γ球蛋白均显著升高（Ｐ＜０．０１），Ａ：Ｇ值（白／球比）显著下降（Ｐ＜０．０１），ＬＤＨ１显著下降（Ｐ＜０．０１），ＬＤＨ２、ＬＤＨ３、ＬＤＨ４、ＬＤＨ５增加，但差异不显著（Ｐ＞０．０５），以上各成分的对应血清值均无显著变化（Ｐ＞０．０５）．关节滑液（ＳＦ）的检测为乳牛关节炎症提供了准确诊断方法和依据，并可揭示关节在病理状态下的代谢状况，具有重要的临床指导意义．     

肝硬化失代偿期患者血清垂体及性激素水平的变化

目的 探索男性肝硬化失代偿期患者血清性激素及垂体激素的变化与肝功能损害程度的关系。方法 应用放射免疫分析法检测４８例男性肝硬化失代偿期患者血清性激素、睾酮（Ｔ）、雌二醇（Ｅ２）、垂体激素、促卵泡生成素（ＦＳＨ）、促黄体生成素（ＬＨ）及催乳素（ＰＲＬ）水平的变化。结果 患者血清Ｔ水平明显降低（Ｐ〈０．００１），而Ｅ２（Ｐ〈０．０１），ＰＲＬ（Ｐ〈０．００１），ＦＳＨ（Ｐ〈０．０５）水平均不同程度高于     

肝癌、肝硬化及慢性肝炎患者血脂及载脂蛋白AI、B_（100）水平的变化

本文对３１例肝癌、３０例肝硬化及３１例慢性肝炎患者进行了血清载脂蛋白（ａｐｏ）ＡＩ、Ｂ＿（１００）及血脂的检测，并与６３例健康成人作比较。结果表明：肝癌、肝硬化及慢性肝炎患者血清总胆固醇（ＴＣ）、高密度脂蛋白胆固醇（ＨＤＬ—Ｃ）和ａｐｏＡＩ都显著的降低，与健康对照组比较，均有极显著性差异（Ｐ＜０．００１）；肝癌及肝硬化患者血清甘油三酯（ＴＧ）都呈不同程度的降低（Ｐ＜０．０１和Ｐ＜０．０５）；肝硬化患者的血清ａｐｏＢ＿（１００）也显著的降低（Ｐ＜０．００１）。本文资料提示，在肝脏疾病时检测血脂及ａｐｏＡＩ、Ｂ＿（１００）含量，可以了解肝实质损伤的程度。     

肺癌患者237例全身骨显像分析

目的探讨SPECT全身骨显像对肺癌患者的临床应用价值。方法回顾性分析我院237例肺癌患者临床资料及全身骨显像情况。结果肺癌237例患者无骨转移者134例（56．5％）；骨转移患者103例（43．5％），其中，腺癌骨转移者49例（20．7％），鳞癌骨转移者30例（12．7％），其它骨转移者24例（10．1％）。骨转移部位：肋骨转移80例，占骨转移患者总数的77．6％（80／103）；脊柱转移54例（52．4％，54／103）；骨盆转移44例（42．7％，44／103）；四肢转移32例（31％，32／103）；颅骨转移11例（10．7％，11／103）。结论全身骨显像对早期发现肺癌骨转移、临床分期、选择治疗方案及判断预后有重要价值。     

幽门螺杆菌与慢性胃炎及十二指肠炎的关系：附376例分析

应用快速尿素酶试验和胃粘膜直接印片的方法，对３７６例确诊为慢性胃炎患者（其中１２３例合并十二指肠炎）的幽门螺杆菌检测，可获得ＨＰ与慢性胃炎及十二指肠炎的关系。慢性胃炎ＨＰ的检出率４９．４％，活动性胃炎ＨＰ的检出率８１．７％（Ｐ＜０．００１），活动性十二指肠炎ＨＰ的检出率８７．５％（Ｐ＜０．００１）．结果表明，ＨＰ与慢性胃炎尤其是活动性胃炎及活动性十二指肠炎有极密切的关系；     

The Structure and Measurement of Self-efficacy

本研究的目的在于以分析自我效能的结构为基础，制订自我效能的测量工具。原始问卷依自我效能的理论定义而构造。１４９名大学生参加了测验。要求被试在６点量表上评定问卷的每一个条目是否适合描述他们自己，“１”代表完全不适合，“６”代表完全适合。被试同时还完成了中国罗特内外控测验、自我差异测验、ＳＣＬ９０抑郁分测验以及Ｓｈｅｒｅｒ的自我效能问卷。测验结果得到了一个由１９个条目构成的单因素结构的自我效能量表，该因素解释总变异的３２４％，量表平均分为６３０９，标准差为１２６４５，无显著性性别差异（ｔ＝０１４，Ｐ＝０８８）。统计分析还表明：该量表具有较好的内部一致性信度（ａ＝０８７８）和重测信度（ｒ＝０８１７）；和外控倾向呈显著性负相关（ｒ＝－０５１１，Ｐ＜０００１），和实际—理想自我差异、实际—应该自我差异也均有显著性负相关（ｒ＝－０４２０，Ｐ＜０００１；ｒ＝－０４５０，Ｐ＜０００１）；和抑郁有显著性负相关（ｒ＝－０３９８，Ｐ＜０００１），有较理想的构想效度；同时，与Ｓｈｅｒｅｒ的自我效能量表中的一般自我效能相关为０６１４０（Ｐ＜００００１），与其社会自我效能相关为ｒ＝０５３７９（Ｐ＜０     

中国癌症与土壤环境中As元素的关系

利用土壤环境中砷元素资料３２３３５个数据,癌死亡调查资料７８７０８０例,研究了胃癌、食管癌、肝癌、宫颈癌、肺癌、大肠癌、白血病、鼻咽癌、乳腺癌死亡率与人群生存区土壤环境中砷元素的关系。结果表明,肺癌、大肠癌、白血病、乳腺癌死亡率与砷元素有相关性,等级相关系数分别为－０．５７９８（Ｐ〈０．００１）,－０．５１２３（Ｐ〈０．００５）,－０．４５９６（Ｐ〈０．０１）,－０．６８２０（Ｐ〈０．０００５）。     

三普虫草精对小鼠免疫功能影响的实验研究

通过检测小鼠脾脏ＰＦＣ,ＣＤ＋４／ＣＤ＋８Ｔ淋巴细胞亚群比值、淋巴细胞转化活性及脾细胞产生肿瘤坏死因子（ＴＮＦ）等免疫指标,观察三普虫草精（ＳＰＣＳ）对环磷酰胺（ＣＹ）损伤小鼠免疫功能的影响。发现ＳＰＣＳ在有效剂量范围内单独使用,能促进ＣＹ损伤小鼠ＰＦＣ功能的恢复（Ｐ＜０．０１）;使因ＣＹ损伤而失调的ＣＤ＋４／ＣＤ＋８Ｔ淋巴细胞亚群比值得到改善（Ｐ＜０．０５）;使降低了的淋巴细胞转化活性得以恢复（Ｐ＜０．００１）;能显著促进ＣｏｎＡ诱导ＣＹ损伤小鼠脾细胞ＴＮＦβ的合成与释放（Ｐ＜０．００１）。     

中药促生汤促小鼠宫颈成熟的实验研究

为研究中药促生中小鼠宫颈成熟的效果及其作用机制，以受孕昆明鼠作为实验对象，放免法检测小鼠血液Ｅ２（雌二醇）Ｐ（孕酮）水平及光镜下观察小鼠宫颈胶原纤维的变化。实验组与对照组相比：Ｅ２水平明显升高（Ｐ〈０．００１），Ｐ水平明显下降（Ｐ〈０．０５），宫颈组织疏松，密度降低，胶原纤维破坏，断裂，排列紊乱，小鼠平均提前两天分娩，幼仔存活率无差别，说明中药促生汤有明显的促宫颈成熟的作用，其作用机制可能是通过改     

牛磺酸与细胞膜自由基损伤的关系

为了探讨牛磺酸与细胞膜自由基损伤的关系，选用脂质过氧化物测定法、溶血试验及谷胱甘肽测定法的指标进行测定，结果显示：牛磺酸加剧了辐射导致的小鼠肝、脑、肾组织的脂质过氧化反应（Ｐ＜００５或Ｐ＜００１）；牛磺酸加剧了辐射导致的人红细胞悬液的溶血作用（Ｐ＜００１或Ｐ＜０００１）；牛磺酸与人红细胞悬液３７℃水浴１ｈ，发现牛磺酸致使红细胞中谷胱甘肽水平显著下降（Ｐ＜０００１）。结果提示，牛磺酸不是自由基清除剂，相反，它能加剧细胞膜的自由基损伤。     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Density Functional Theory for the Response of Periodic Systems to Electric Fields Based on the Vector Potential Approach

正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that     

On the Thermodynamic Limit for Responses to Static Electromagnetic Fields

For molecular systems,the quantum-mechanical treatment of their responses to static electromagnetic fields usually employs a scalar-potential treatment of the electric field and a vector-potential treatment of the magnetic field.Although the potential for each field separately is associated with the choice of an(unphysical)origin,the precise choice of the origin for the electrostatic field has little consequences for the results.This is different for the     

An affordable accurate evaluation of the binding conformations predicted by molecular docking studies in bio-system

Franck-Condon factors bridge the gap between theoretical modeling and experimental observations for molecular electronic spectroscopy and electron transfer.Under the displaced harmonic oscillator approximation,multidimensional Franck-Condon factors are decomposed into a product of many one-dimensional(1D)Franck-Condon(FC)factors,and each 1D-FC factor is associated with one Huang-Rhys factor that determines the leading contribution of     

Call for Papers

<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with