Windows9X的注册表结构分析

以Windows98操作系统的注册表为基础，分析了Windows9X的注册表与与Windows98操作系统之间的关系，注册表的结构及各根键的作用，介绍了注册表的组成等，为用户在计算机使用过程中提供了方便，使用户能充分利用注册表，提高系统的性能，达到了优化系统，使系统稳定运行的目的。     

USP理论的应用及其误区

USP，是不朽的广告智慧。在当今日益激烈的品牌竞争环境中，我们没有比今天更需要USP的了。然而，在实践中我们对它的使用存在一些误区。在产品日益同质化的今天，我们应怎样避免误区，将其运用得恰到好处、淋漓尽致，本对此作了深入探讨并提出了三条思路。     

Windows9X与Windows2000/XP注册表剖析

系统安全是电脑使用中的一个重要问题。了解注册表的结构,熟悉注册表的应用,安全有效地使用电脑,对 Windows 用户有很重要的意义。     

Windows9.X环境下开发测试ASP

在Windows9.X环境下开发、测试ASP,提出了以VisualInterDev6.0为开发环境,以PWS测试环境的处理方法.     

利用WIN9X系统策略管理公用计算机

本文阐述了一种利用中文Windows 9x系统策略管理公用计算机的方法，并给出了较详细的实施方案。     

USP低温改性沥青及沥青混合料性能研究

节能环保、低碳施工是我国现阶段工程建设过程中积极倡导的施工工艺.为测试USP低温改性沥青混合料的使用性能,本研究对其马歇尔稳定度、残留稳定度、高温稳定性、冻融劈裂、劈裂强度、渗水性进行试验分析,结果显示,USP低温沥青混合料具有较好的抗水毁能力,掺入USP改性沥青能够提高沥青混合料的低温疲劳性能,改善沥青混合料抵抗外力破坏性能.     

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid.

Retinoid response pathways are mediated by two classes of receptors, the retinoic acid receptors (RARs) and the retinoid X receptors (RXRs). A central question is whether distinct response pathways are regulated by these two classes of receptors. The observation that the stereoisomer 9-cis-retinoic acid binds with high affinity to RXRs suggested that this retinoid has a distinct role in controlling RXR activity, but it was almost simultaneously discovered that RXRs function as auxiliary receptors for RARs and related receptors, and are essential for DNA binding and function of those receptors. Hence, although RARs seem to operate effectively only as heterodimeric RAR/RXR complexes, RXRs themselves apparently function predominantly, if not exclusively, as auxiliary receptors. Here we report that 9-cis-retinoic acid induces RXR homodimer formation. Our results demonstrate a new mechanism for retinoid action by which a ligand-induced homodimer mediates a distinct retinoid response pathway.     

Windows 9X系统中的DOS汉字输入方法

介绍了Windows9X系统中MS－DOS方式下中文输入法的使用，并且讨论了可能出现的问题与解决方法。     

The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X

We constructed maps for eight chromosomes (1, 6, 9, 10, 13, 20, X and (previously) 22), representing one-third of the genome, by building landmark maps, isolating bacterial clones and assembling contigs. By this approach, we could establish the long-range organization of the maps early in the project, and all contig extension, gap closure and problem-solving was simplified by containment within local regions. The maps currently represent more than 94% of the euchromatic (gene-containing) regions of these chromosomes in 176 contigs, and contain 96% of the chromosome-specific markers in the human gene map. By measuring the remaining gaps, we can assess chromosome length and coverage in sequenced clones.     

X01新型粘结剂的研制

本文研究了聚乙烯醇缩甲—丁醛的缩合条件及其对内外墙涂料抗老化、耐擦洗等性能的影响,指出上述缩合物是一种应用性能和经济效益都很理想的粘结剂。     

The Bloom's syndrome helicase suppresses crossing over during homologous recombination

Mutations in BLM, which encodes a RecQ helicase, give rise to Bloom's syndrome, a disorder associated with cancer predisposition and genomic instability. A defining feature of Bloom's syndrome is an elevated frequency of sister chromatid exchanges. These arise from crossing over of chromatid arms during homologous recombination, a ubiquitous process that exists to repair DNA double-stranded breaks and damaged replication forks. Whereas crossing over is required in meiosis, in mitotic cells it can be associated with detrimental loss of heterozygosity. BLM forms an evolutionarily conserved complex with human topoisomerase IIIalpha (hTOPO IIIalpha), which can break and rejoin DNA to alter its topology. Inactivation of homologues of either protein leads to hyper-recombination in unicellular organisms. Here, we show that BLM and hTOPO IIIalpha together effect the resolution of a recombination intermediate containing a double Holliday junction. The mechanism, which we term double-junction dissolution, is distinct from classical Holliday junction resolution and prevents exchange of flanking sequences. Loss of such an activity explains many of the cellular phenotypes of Bloom's syndrome. These results have wider implications for our understanding of the process of homologous recombination and the mechanisms that exist to prevent tumorigenesis.     

The RAG2 C terminus suppresses genomic instability and lymphomagenesis

Misrepair of DNA double-strand breaks produced by the V(D)J recombinase (the RAG1/RAG2 proteins) at immunoglobulin (Ig) and T cell receptor (Tcr) loci has been implicated in pathogenesis of lymphoid malignancies in humans and in mice. Defects in DNA damage response factors such as ataxia telangiectasia mutated (ATM) protein and combined deficiencies in classical non-homologous end joining and p53 predispose to RAG-initiated genomic rearrangements and lymphomagenesis. Although we showed previously that RAG1/RAG2 shepherd the broken DNA ends to classical non-homologous end joining for proper repair, roles for the RAG proteins in preserving genomic stability remain poorly defined. Here we show that the RAG2 carboxy (C) terminus, although dispensable for recombination, is critical for maintaining genomic stability. Thymocytes from 'core' Rag2 homozygotes (Rag2(c/c) mice) show dramatic disruption of Tcrα/δ locus integrity. Furthermore, all Rag2(c/c) p53(-/-) mice, unlike Rag1(c/c) p53(-/-) and p53(-/-) animals, rapidly develop thymic lymphomas bearing complex chromosomal translocations, amplifications and deletions involving the Tcrα/δ and Igh loci. We also find these features in lymphomas from Atm(-/-) mice. We show that, like ATM-deficiency, core RAG2 severely destabilizes the RAG post-cleavage complex. These results reveal a novel genome guardian role for RAG2 and suggest that similar 'end release/end persistence' mechanisms underlie genomic instability and lymphomagenesis in Rag2(c/c) p53(-/-) and Atm(-/-) mice.     

预处理方法对细菌降解玉米秸秆产氢能力的影响

为提高细菌降解玉米秸秆产氢能力,实验研究了酸化汽爆预处理、硫酸预处理、氢氧化钠预处理和氨水预处理4种预处理方法对细菌Clostridium sp.X9降解玉米秸秆发酵产氢能力的影响.结果表明,酸化汽爆为最佳的预处理方式.在酸化汽爆预处理条件为硫酸体积分数1%、汽爆温度121℃和汽爆时间2 h时,纤维素降解产氢细菌Clostridium sp.X9利用酸化汽爆玉米秸秆产氢获得的最大产氢率和玉米秸秆降解率分别为6.4 mmol/g和47.8%.液相代谢末端产物主要为丁酸、乙酸和乙醇.     

含有XW_9O_(33)~(9-)(X=As~Ⅲ,Sb~Ⅲ,Bi~Ⅲ)杂多钨酸盐的研究进展

~~1.2　 {As W9O3 3 }2由过渡金属等连接两个 As W9O3 3 9-可形成夹层型结构聚阴离子 .图 2示出了 As2 W2 1O69( H2 O) 6-的结构 [11] ,夹层中的 3个 W可以被其他的过渡金属等离子或基团所取代 ,从而形成单取代、双取代和三取代夹心型化合物 ,如单取代化合物 [As2 MW2 0 O68( H2 O) 2 ]8-( M=Co2 + ,Zn2 + ) [12 ] ,双取代化合物 [( α-As W9O3 3 ) 2 WO ( H2 O) M2 ( H2 O) 2 ]10 -( M =Zn2 + ,Mn2 + ) [13 ] ,[( Hg2 ) 2 WO( H2 O) ( As2 W9O3 3 ) 2 ]10 -[14 ](图 3) ,[{( ph Sn ) 2 O2 }2 H (α- As W9O3 3 ) 2 ]9-…     

The DNA sequence of the human X chromosome

The human X chromosome has a unique biology that was shaped by its evolution as the sex chromosome shared by males and females. We have determined 99.3% of the euchromatic sequence of the X chromosome. Our analysis illustrates the autosomal origin of the mammalian sex chromosomes, the stepwise process that led to the progressive loss of recombination between X and Y, and the extent of subsequent degradation of the Y chromosome. LINE1 repeat elements cover one-third of the X chromosome, with a distribution that is consistent with their proposed role as way stations in the process of X-chromosome inactivation. We found 1,098 genes in the sequence, of which 99 encode proteins expressed in testis and in various tumour types. A disproportionately high number of mendelian diseases are documented for the X chromosome. Of this number, 168 have been explained by mutations in 113 X-linked genes, which in many cases were characterized with the aid of the DNA sequence.     

基于WIN 9X／NT的机器人控制器高层软件系统的研发技术

介绍基于工控微机（IPC）和WIN 9X／NT操作系统的工业机器人控制高层软件系统的研发技术,详细介绍了机器人软件系统第二层的模块组成和实现方案,并讨论了开发过程中的关键技术。