结构基因组学研究中的亲和接头

介绍了亲和接头在高通量生产目标蛋白质中的运用,这些亲和接头包括6组氨酸、麦芽糖结合蛋白、谷胱甘肽-S-转移酶和硫氧还蛋白,并讨论了高通量生产的蛋白质的溶解和复性.     

结构基因组学研究中的亲和接头

运用AHP方法和ANP方法确定企业可持续发展评价指标权重,并比较两种方法对排序结果的影响。研究表明,与AHP的结果比较,ANP方法得出的指标权重趋向均衡化,增强了指标权重的可行性和合理性。运用ANP方法评价企业可持续发展更合理。     

结构基因组学综合数据库分析的构建和作用

介绍了结构基因组学综合数据库构建的意义和综合数据库的功能,主要包括Gerstein总结的对有限的蛋白质片段的折叠分类和排列、种系发生信息、蛋白质的功能分类和蛋白质的相互作用信息、基因表达信息和综合数据库对报道结构基因组研究数据和格式的要求。     

DNA和RNA的结构基因组学研究的应用前景

人类基因组计划的实施产生了大量的基因数据，如何利用这些数据是后基因时代生物学研究的主要内容。结构基因组学就是利用这些数据和计算机模拟技术建立模型来为人类服务，介绍了DNA和RNA的结构基因组学的主要研究内容和进展，讨论了结构基因组学的商业应用前景。     

国际石油价格波动的结构性因素分析

文章将石油供给性冲击、需求性冲击和投机行为冲击3方面结构性因素细分为5个内生变量,构建反映油价波动的结构向量自回归(SVAR)模型,并运用模型对1999—2012年期间油价波动的原因进行了实证分析。结果表明:需求性冲击无论是长期还是短期都是油价波动的最主要因素;其次,投机性冲击对油价波动的影响也较大,不容忽视;短期突发事件和供给冲击短期对油价有些影响,长期影响基本消失。     

Prioritizing global conservation efforts

One of the most pressing issues facing the global conservation community is how to distribute limited resources between regions identified as priorities for biodiversity conservation. Approaches such as biodiversity hotspots, endemic bird areas and ecoregions are used by international organizations to prioritize conservation efforts globally. Although identifying priority regions is an important first step in solving this problem, it does not indicate how limited resources should be allocated between regions. Here we formulate how to allocate optimally conservation resources between regions identified as priorities for conservation--the 'conservation resource allocation problem'. Stochastic dynamic programming is used to find the optimal schedule of resource allocation for small problems but is intractable for large problems owing to the "curse of dimensionality". We identify two easy-to-use and easy-to-interpret heuristics that closely approximate the optimal solution. We also show the importance of both correctly formulating the problem and using information on how investment returns change through time. Our conservation resource allocation approach can be applied at any spatial scale. We demonstrate the approach with an example of optimal resource allocation among five priority regions in Wallacea and Sundaland, the transition zone between Asia and Australasia.     

RIKEN介观器件腔中粒子逃逸曲线的无标度区研究

RIKEN介观器件腔中的粒子逃逸曲线存在混沌性质,是研究分形及自相似结构的理想模型。本文通过对混沌逃逸曲线及无标度区的研究,发现自相似结构并用相似比进行了定义。通过不同自相似结构的对比,发现同一无标度区内相似比具有恒定性,并得到了相似比与分形维数的线性关系。该研究使相似比成为定量描述无标度区以及混沌性质的手段,为混沌性质的表征提供了新的方法。     

From genomics to proteomics

Proteomics is the study of the function of all expressed proteins. Tremendous progress has been made in the past few years in generating large-scale data sets for protein-protein interactions, organelle composition, protein activity patterns and protein profiles in cancer patients. But further technological improvements, organization of international proteomics projects and open access to results are needed for proteomics to fulfil its potential.