The adenohypophysial hormone content of the rat pars tuberalis.

The pars tuberalis of the hypophysis was shown to contain LH, which increases after castration, TSH and a very low amount of PRL. FSH was found after castration.     

Luteinizing hormone content of the pars tuberalis of the hypophysis of neonatally androgenized female rats

Summary The immunoreactive LH content of the pars tuberalis of neonatally androgenized female rats was studied and found to be significantly lower than that of control females at oestrus or of control males. It is concluded that the rat pars tuberalis does secrete LH and that this secretory activity is diminished by neonatal androgenization in a manner that differs from that reported for the LH secretion in the pars distalis.This investigation received financial support from Direccion de Investigacion, grants RMS-80-13 and S-80-26, Universidad Austral de Chile.     

Hypothalamic nerve fibres in the pars tuberalis and pia-arachnoid tissue of the cat and their degeneration pattern after a lesion in the hypothalamus

Zusammenfassung Mit der Bielschowsky-Gros-Methode wurden bei Katzen Nervenfasern untersucht, die vom Infundibulum in die Pars tuberalis ziehen. Die Befunde an normalen Tieren und an einer Katze mit einer Hypothalamus-Läsion zeigen, dass eine beachtliche Zahl hypothalamischer Fasern in verschiedene Teile der Pars tuberalis, sowie in das Gewebe der Pia und der Arachnoidea übergehen.Bei der operierten Katze wurde das Degenerationsbild der in den dorsalen Teil der Pars tuberalis ziehenden Hypothalamus-Fasern beschrieben.     

The effect of the ergoline derivative VUFB-6683 on the adenohypophysial prolactin concentration in rats

Zusammenfassung Mit Hilfe vond-6-Methyl-8-ergolin-I-ylacetamid-Tartarat, VUFB-6683 wurde bei säugenden Ratten das Gewicht und der Prolaktinspiegel der Adenohypophyse herabgesetzt und die Laktation gehemmt.

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The authors are indebted to Dr.I. J. Skála, Dr.J. Hondlík, Mrs.V. Maitová and Mrs.J. Emanuelová for technical assistance; and to Dr.I. Mikulá for his aid in designing the study.     

Age-and sex-related development of ACTH in the pars distalis and neurointermedia of rat pituitary]

The content of ACTH of the pars distalis and neurointermedia of the pituitary of adult Rats is higher in the male than in the female. This differenciation of content, according to sex, appears at puberty at the site of pars distalis; it only appears around the 60th day of life at the site of the pars intermedia. The androgens seem to be responsible for the higher percentages observed in the males.     

Relationship between the pars intermedia and the pars nervosa in the hypophysis of an antarctic seal

Resumen La pars intermedia de la hipófisis de la foca de Weddell (Leptonychotes weddelli) presenta trabéculas que irrumpen en la Pars nervosa. En estas trabéculas epiteliales se encuentran grumos y fibras de materialGömöri positivo. Este material no fué hallado en ninguna otra región de la adenohipófisis.

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This work has been carried out at the Scientific Station Almirante Brown in Antarctica during the Antarctic year 1966. It was supported by the Instituto Antártico Argentino. Contribución del Instituto Antártico Argentino No. 120.     

Converting enzyme content of different tissues of the rat

Résumé On a dosé l'enzyme de conversion dans différents tissus du rat au moyen d'une méthode chimique mesurant la libération d'histidyl-leucine à partir du substrat synthétique Z-phe-his-leu. Le poumon contient au moins 8 fois plus d'enzyme que tous les autres tissus étudiés. Il en contient notamment plus de 100 fois plus que le foie.     

The content of noradrenaline and adrenaline in the rat heart after administration of rauwolfia alkaloids

Zusammenfassung Die chemisch verwandten Rauwolfia-Alkaloide Raunescin, Isoraunescin, Deserpidin, Rescinnamin und Reserpin verursachen einen starken Abfall des Noradrenalingehaltes des Rattenherzens, wenn sie intraperitoneal in einer Dosis von 5 mg/kg gegeben werden. Der Adrenalingehalt wird nicht deutlich oder einheitlich ver?ndert. α-Yohimbin, das chemisch zu einer andern Gruppe geh?rt, hat keine Wirkung auf den Noradrenalingehalt des Herzens.

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This work was supported by a grant from the U. S. Public Health Service (H-2205) and by funds from the Eugene Higgins Trust.     

The role of parathyroid hormone and calcitonin in magnesium absorption in the rat small intestine

Summary We studied duodenal and ileal magnesium (Mg) absorption in intact, parathyroidectomized (PTX), thyroid-(TX) and thyroparathyroidectomized (TPTX) rats with iodine hormones replaced, and, additionally, in PTX rats receiving bovine parathyroid hormone 1–34 and 1,25-dihydroxyvitamin D₃, respectively. Ma absorption was reduced after PTX and TPTX in the duodenum, but not in the ileum, whereas TX had no influence on duodenal or ileal Mg absorption. Both bovine parathyroid hormone 1–34 and 1,25-dihydroxyvitamin D₃ increased Mg absorption in the duodenum and the ileum in PTX rats.Acknowledgments. We are grateful to B. Schreiber, K. Schwille and I. Goldberg for technical and secretarial help. Supported by Deutsche Forschungsgemeinschaft (Schw 210/3). Reprint requests to P.O.S., University Hospital, Maximiliansplatz, D-8520 Erlangen.     

Effect of copulation or vaginal stimulation on melanocyte-stimulating hormone content of the hypophysis

Résumé Dans le rat, 1 h après la copulation, la concentration de l'MSH de l'hypophyse présente une diminution statistiquement significative, autant chez le mâle que chez la femelle. La stimulation vaginale avec une baguette de verre provoqua 60 et 120 min plus tard une diminution de la concentration de plus de 50% de l'MSH de l'hypophyse. Au bout de 30 min, on n'a observé aucun changement. On en déduit que la copulation ou la stimulation vaginale libère l'MSH.

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This investigation was supported by grant No. NB 04732-03 from the NIH, US. Public health Service.     

The effect of corticotrophine on free fatty acid content in rat adrenal

Zusammenfassung Es wurde die Wirkung von ACTH auf den Gehalt unveresterter Fettsäuren in Rattennebennieren verfolgt. Nach Injektion von 2 IE ACTH per 100 g Körpergewicht (1, 2, 6 und 12 h post inj.) findet in der Nebennierenrinde keine Abnahme an freien Fettsäuren statt.     

Control of corpus allatum activity inDiploptera punctata: roles of the pars intercerebralis and pars lateralis

Summary Control of the corpora allata (CA) ofDiploptera punctata is maintained by at least 2 factors. The glands are directly inhibited by an allatostatin arriving at the CA via the nervi corporis cardiaci I (NCC I). Destruction of the putative source (median neurosecretory cells, MNC) of the allatostatin by radio-frequency (RF) cautery relieved the inhibition imposed on the CA of virgin females, and the glands became active. Similarly, destruction of the lateral neurosecretory cells (LNC) also relieved the inhibition. We propose that the LNC stimulated the MNC to release allatostatin. RF-cautery did not result in the activation of CA of pregnant or ovariectomized females. Activation of the CA may therefore require not only absence of the inhibitory factor but also the presence of a stimulatory one (perhaps from the ovary).