Autoradiographische Studien über die DNS-Synthese im Hypophysenvorderlappen der Ratte

Summary By autoradiographic studies with H³-thymidine it is demonstrated that the percentage of labelled nuclei is very low in the anterior pituitary of normal untreated rats and of rats 14 days after thyreoidectomy. Following castration, however, a marked increase of DNA-synthesizing cells occurs as well as an increase of mitotic figures.

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Mit Unterstützung durch die Deutsche Forschungsgemeinschaft und das Bundesministerium für Wissenschaftliche Forschung.     

Quantitativer Nachweis eines Abbaus von Zellulose und Lignin in der rollkranken Rebe

Summary In leafroll-diseased grapevines, lignine and cellulose decompose anomalously. Therefore leaves and shoots of these vines curl characteristically down and inward. As a specific intermediate product, 4-methyl-d-glucuronic acid has been identified. The decomposition increases proportionally to the progress of the infection.     

Nachweis einer nichtlinearen Komponente im globalen ERG der Katze bei Zuwachsreizen

Summary Nonlinear responses may be produced by incremental stimuli in the global electroretinogram of strongly light-adapted cat.     

Kristalloide Einschlüsse im Karyoplasma von Spermatiden eines Myriapoden

Summary In the caryoplasm of the early spermatids of a Diplopode, there is a crystalloid inclusion which is accompanied by a linear bundle of filaments.     

Die Zucht vonLytta vesicatoria im Laboratorium und Nachweis der Cantharidinsynthese in Larven

Summary Adult males ofLytta vesicatoria (Coleopt., Meloidae) synthesize cantharidin, but females do not, although the substance is present in the females too. We developed a method for rearing larvae of this parasitic beetle in the laboratory. It is shown that there exist 7 larval stages and 4 hypermetamorphic forms (triungulinus, second larva,pseudochrysalis and fourth larva). Larvae from the second to the fifth stage (second larva) synthesize cantharidin. Therefore, we conclude that the substance present in the adult female is at least in part synthesized in the larval period. Nothing is known about the biological significance of this biochemical sexual dimorphism.

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Coleoptera, Meloidae.     

Nachweis von radioaktiven Aminosäuren im Kollagen nach Gabe von Prolin-C14

Summary Beside hydroxyproline collagen contains quantities of glutamine, threonine, serine, alanine and glycine, derived from proline. Remarkably large quantities of threonine have this origine, which suggests that conversions occur in the fibroblast.     

Papierchromatographischer Nachweis freier Aminosäuren im Knochenmark einiger Tiere während verschiedenen Jahreszeiten

Summary The qualitative identity of the free amino acids in some animal species was proved by means of paper chromatography.     

Untersuchungen zum Nachweis spezifischer Perzeptionsmechanismen im Drucksinn sessiler Krebse (Balanus balanus L. undBalanus improvisus Darwin)

Summary The mechanism of pressure sensitivity in marine invertebrates without gasfilled spaces is still obscure. Barmacles sum up supra- and subthreshold pressure stimuli with supra- and subthreshold shade stimuli. The subthreshold spatial summing up indicates that specific pressure receptors or receptor mechanisms exist.

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Gefördert von der Deutschen Forschungsgemeinschaft.     

Nachweis vonn-Butylamin in Äpfeln

Summary n-Butylamine, a new biogenic amine could be identified in apples by means of paper chromatography and micro-cristallography.     

Zum Nachweis von Aminen im 10−10-Mol-Maßstab. Trennung von 1-Dimethylamino-naphthalin-5-sulfonsäure-amiden auf Dünnschichtchromatogrammen

Summary For the sensitive determination of amines their 1-dimethyl-amino-naphthalene-5-sulphonyl derivatives were separated in two-dimensional thin-layer chromatograms. 10^–10–10^–11 mole per amine can be detected, when the fluorescence of the DANSyl-compounds is excited by the 365 mµ Hg line.     

Nachweis neuer Spurenkomponenten des Actinomycin-C-Komplexes

Summary After Craig distribution in our system 43 of actinomycin C, furnishing high-values for the components of actinomycin, traces of new components of the actinomycin C complex could be demonstrated by paper chromatography.     

Zentralerregende Wirkung eines neuen Piperidinderivates

Summary A new piperidine derivative, the 2-diphenylmethylpiperidine, produces already in doses of 0.001 g/kg s.c. a strong increase of the spontaneous motility of various animals. On mice it has about the same potency as d-desoxy-ephedrine and is about 3 times more potent than amphetamin. It also acts markedly antagonistic on various narcotics but has practically no peripheral sympathomimetic effects.

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8. Mitteilung über Alkylenimin-Derivate. 7. Mitteilung sieheB. M. Iselin undK. Hoffmann, J. Am. Chem. Soc.76 (im Druck).     

Nachweis von Kuhmilchantikörpern mittels latex

Summary The latex method is able to demonstrate antibodies against cows' milk. We suppose that other antigen-antibody reactions are also detectable by the latex method. The question whether this method is more specific and more able to prove that the antibodies show diagnosis, is an open one, in the same way as the other well-known immunological reactions.     

Nachweis einer reflektorischen Natur der Jodazetat-Miosis

Summary Intravenous administration of iodoacetate (20 mg/kg) produces in cats a transient miosis. This is shown to be a reflex constriction elicited by an excitatory action of iodoacetate on the retina.     

Zum Nachweis von Aminosäuren im 10−10-Mol-Maßstab. Trennung von 1-Dimethylamino-naphthalin-5-sulfonyl-aminosäuren auf Dünnschichtchromatogrammen

Summary Some solvent systems are described for the separation of 1-dimethyl-amino-naphthalene-5-sulphonylamino acids on thin layer chromatograms. 10^–10 mole per amino acid can be detected on a two-dimensional chromatogram, when the yellow fluorescence of these compounds is excited by a UV-lamp.     

Nachweis von3H-Digitoxin in der Herzmuskelzelle

Summary In autoradiographs of intraventricular muscle bundles of beef heart, tritiated digitoxine is found outside the membrane and inside the muscle cell at the moment of maximal inotropic action.     

Zur Mikroabsorptionsspektralanalyse im sichtbaren Spektralgebiet und im UV

Summary A new instrument for the U.V. spectrometry of microscopic preparations, which uses quartz objectives not only for magnification, but also for monochromatization, permits measurements up to extinctionsE of more than 2.

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Mit Unterstützung der Ciba-Stiftung für chemische, mediziinsche und technische Forschung.     

Nachweis pflanzlicher Ribonukleasen in Polyacrylamid-Gelen nach Disk-Elektrophorese

Summary Detection of ribonucleases in polyacrylamide gels after disc-electrophoresis is possible by incubation of the gels in a solution of low molecular RNA followed by staining with methylene blue. Application of this method to protein extracts of wheat leaves, sugar beet leaves and roots of different bean varieties as well as callus cultures and roots of the same bean variety shows differences in number and position of RNase zones.     

Untersuchungen zur biologischen Wirksamkeit eines A-homo-Testosteronacetates

Summary The biological efficiency of a high purified A-homo-testosterone-acetate was tested on male mice. We found no inhibition of the gonadotropic partial-function of the anterior pituitary by the substance; and furthermore no substitution of testosterone deficit after castration was possible.