共查询到20条相似文献，搜索用时 15 毫秒
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Some studies have shown that native Chinese speakers have different laterality in matched Stroop tasks from native English speakers.Recently,many imaging data,which show left laterality of English-matched Stroop interference,have been reported.And a few functional imaging studies have been conducted to investigate the phenomenon of the Chinese version of Stroop task.In this study,functional activity in the lateral prefrontal cortex of a group of normal Chinese boys with functional near-infrared imaging during a Stroop color-word task was measured to show different Stroop interferences in the prefrontal cortex.The results show obvious fluctuation of the cerebral blood volume in the right prefrontal cortex in all boys,which agrees with the finding of previous studies,that is,Chinese native boys have right laterality in their brain when the Chinese version of Stroop color-word task is applied. 相似文献
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利用前额叶脑区过量表达β钙离子/钙调素依赖的蛋白激酶II(βCaMKII)的蛋白修饰转基因小鼠,研究βCaMKII对小鼠工作记忆的影响.Western Blot结果显示,转基因小鼠前额叶脑区的βCaMKII过量表达.在修饰的水迷宫实验中,与对照组相比,转基因小鼠的逃避潜伏期没有发生明显变化.此外,在T迷宫实验中,转基因小鼠的正确率与对照组的正确率也基本相同.由此推测,βCaMKII的过量表达对于前额叶皮层依赖的工作记忆没有明显的影响. 相似文献
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目的 通过正常人群了解Stroop测验的结果是否存在性别、年龄和学历上存在差异;通过单纯额叶、颞叶和顶叶卒中的病人了解是Stroop测验可能的神经功能区域.方法 研究采用中文版Stroop测验和简易智能量表,数据处理采用SPSS13.0软件据包进行分析和处理.结果 正常人Stroop测验结果与性别无关（P〉0.05）,与年龄有关（P 〈0.05）,与教育程度有关（P 〈0.05）.卒中的病人按照左右半球损害分组无差异（P 〉0.05）,按照损害额叶、颞叶和顶叶分组无差异（P 〈0.05）.结论 正常人群Stroop测验结果与年龄和学历有关,无性别的差异.Stroop测验结果没有左右半球的差异,但是存在功能分区的差异,在额叶、颞叶和顶叶中,额叶的影响可能更大. 相似文献
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抑郁症患者通常表现出心境低落,并且伴随许多认知和生理症状. 文中使用功能性近红外光谱成像技术(fNIRS)来测量28名抑郁症患者和30名对照组8 min前额皮层的自发血液动力活动. 通过图论和拓扑分析对大脑前额皮层静息态网络属性进行分析,结果表明,抑郁症患者前额皮层网络表现出异常的模式：显著降低的网络密度（低的平均节点等级）、显著降低的聚集程度（低的聚类系数）、显著降低的网络信息传输效率（高的平均路径长度）以及显著增加的随机性（低的小世界属性）. 这些结果表明使用近红外光谱技术能够揭示抑郁症患者脑网络的异常特性. 相似文献
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目的:研究甘氨酸对大鼠前额叶皮质锥体神经元串连动作电位的影响。方法:大鼠前额叶皮质切片,全细胞膜片钳记录锥体神经元串连动作电位。结果:甘氨酸(300μmol/L)可显著降低大鼠前额叶皮质锥体神经元串连动作电位的发放频率,其作用可被番木鳖碱(1μmol/L)所阻断,表明其作用部位为番木鳖碱依赖性甘氨酸受体。甘氨酸还引起膜超极化,延长动作电位的潜伏期,加快复极化进程。结论:前额叶皮质的甘氨酸受体可能在VTA-NAcc-PFC神经环路的调控中发挥重要作用。 相似文献
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实验在40只成年SD大鼠上进行,使用常规电生理学方法,观察了电刺激大鼠内侧额叶前皮质(medial prefrontal cortex, mPFC)对听皮层神经元听反应的影响.在122个神经元上观察了电刺激mPFC对听反应的影响.对其中93个神经元作了详细分析发现,有73个神经元的听反应受到易化（39个,41.9%）或抑制（34个,36.6%）.刺激mPFC对听反应的影响存在最佳刺激间隔,大多数神经元（51个,69%）在10~15 ms之间.结果提示,大鼠mPFC可对听皮层神经元的听反应调制,这种调制可能是通过多级神经元环路实现的. 相似文献
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用前脑特异性NR1基因敲除小鼠,采用离体脑片场电位技术,研究了NR1亚基在前额叶脑区突触可塑性中的作用.刺激强度—反应(input-output curve)和双脉冲抑制反应(paired pulse depression, PPD)的结果表明,与同窝对照组小鼠相比,NR1基因敲除小鼠前额叶脑区的基本突触传递无明显变化.采用高频刺激(100 Hz, 1 000 ms ×2, 间隔30 s)在小鼠的前额叶脑区诱导长时程增强(long-term potentiation, LTP),与对照组小鼠相比,NR1基因敲除小鼠前额叶脑区的LTP明显受损.以上数据提示,NR1亚基在前额叶脑区LTP的诱导中起着重要的作用. 相似文献
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Interference effects are commonly observed when conflicts arise between task-relevant and task-irrelevant dimensions of stimuli. Compared with responses to congruent trials in which the two dimensions are compatible, responses to incongruent trials are usually slower and less accurate. Moreover, the performance in a given trial is affected by the nature of the preceding trial, in that the interference effect for the current incongruent trial is reduced when it follows an incongruent trial than when it follows a congruent one. This conflict adaptation effect has been generally ascribed to the functioning of the cognitive control system, in which higher controls are recruited after conflicts to further constrain the processing of the task-irrelevant dimension. However, due to its uniqueness in neural and cognitive processes, whether the perception of emotional valence shows the same conflict adaptation effect in the conflicting context is an open question. This study adopted a variant of the Stroop task in which the task-relevant dimension was the affective facial expression while the task-irrelevant dimension was the meaning of an emotional word superimposed on the face. Results suggest that the perception of emotional valence in the conflicting context can have aspects that are both similar and dissimilar to the control of conflict for non-emotional information. The capturing of attention by emotional information can alter the functioning of the cognitive control system. 相似文献
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Interference effects are commonly observed when conflicts arise between task-relevant and task-irrelevant dimensions of stimuli. Compared with responses to congruent trials in which the two dimensions are compatible, responses to incongruent trials are usually slower and less accurate. Moreover, the performance in a given trial is affected by the nature of the preceding trial, in that the interference effect for the current incongruent trial is reduced when it follows an incongruent trial than when it follows a congruent one. This conflict adaptation effect has been generally ascribed to the functioning of the cognitive control system, in which higher controls are recruited after conflicts to further constrain the processing of the task-irrelevant dimension. However, due to its uniqueness in neural and cognitive processes, whether the perception of emotional valence shows the same conflict adaptation effect in the conflicting context is an open question. This study adopted a variant of the Stroop task in which the task-relevant dimension was the affective facial expression while the task-irrelevant dimension was the meaning of an emotional word superimposed on the face. Results suggest that the perception of emotional valence in the conflicting context can have aspects that are both similar and dissimilar to the control of conflict for non-emotional information. The capturing of attention by emotional information can alter the functioning of the cognitive control system. 相似文献
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在综述食物决策的认知神经机制、运动干预与食物决策交互作用的基础上,提出了运动改善肥胖人群食物决策的认知神经机制框架,认为运动可能通过改善肥胖人群的执行控制网络进而改善食物决策;回顾了不同剂量的运动影响肥胖人群食物决策的研究成果,发现持续20 min以上、中至高强度的运动可能对肥胖人群的食物决策产生积极效应。 相似文献
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ZHU Ying 《自然科学进展(英文版)》2004,14(4):296-302
This paper reviews some basic findings and methodological issues in neuroimaging studies of self-referential processing.As a general rule,making judgments about one's self,inclusive of personality trait adjectives or current mental states(person's prefer ences,norms,aesthetic values and feeling)uniformly generates medial prefrontal activations,regardless of stimulus materials(words or pictures)and modality(visual or auditory).Cingulate activations are also observed in association with most self-referential processing.Methodological issues include treating self-referential processing as either representing one's own personality traits or representing one's own current mental states.Finally,self-referential processing could Be considered as implement of \"I think therefore I am\" approach to neuroimaging the self. 相似文献
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大脑前额叶扣带回皮层是一个与感觉功能密切相关的脑区,它能够对丘脑触觉反应进行调制.实验在10只戊巴比妥钠（1%）麻醉的SD雄性大鼠上进行,采用辣根过氧化物酶（horseradish peroxidase,HRP）逆行标记的方法,对扣带皮层前部调制丘脑腹侧基底核（ventrobasal,VB）感觉信息的途径进行了研究.实验结果显示,VB核可以接受扣带皮层后部的投射,而且扣带皮层前部有纤维投射到扣带皮层后部.由此提示了前扣带皮层对丘脑腹侧基底核神经元触觉信息调制的可能神经环路是：扣带皮层前部-扣带皮层后部-丘脑腹侧基底核. 相似文献
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探讨正常育龄妇女月经周期对情绪冲突的影响,以及不同时期的情绪注意偏向.研究采用重复测量设计的词-面孔Stroop任务,分析比较了21名被试在卵泡期和黄体期完成情绪判断任务和性别判断任务的正确率和反应时.结果发现:被试在两个任务中均表现出明显的情绪Stroop效应;在情绪判断任务中,月经周期对情绪冲突Stroop任务的影响有统计学意义(p<0.01),在黄体期被试的情绪Stroop效应更加明显,对负性和正性情绪面孔识别的正确率和反应时均存在统计学意义(p<0.01);在性别判断任务中发现,与黄体期相比,女性在卵泡期对男性面孔的识别正确率较高,反应时较短.研究结果表明:女性在黄体期的认知控制能力较卵泡期下降,同时对负性情绪表现出明显的注意偏向;卵泡期女性对男性面孔的偏好大于黄体期女性. 相似文献
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将引导任务与图-字Stroop任务相结合,通过考察不同引导任务对Stroop效应的影响来探讨注意是否影响自动化加工,以及如何影响的问题,以进一步验证注意力敏感模型.两个实验的结果发现:引导任务与Stroop任务中的条件匹配之间存在显著的交互作用;不同引导任务对Stroop效应量的影响不同,语义引导任务下的Stroop效... 相似文献
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研究比较大鼠在静息状态下和工作记忆编码阶段腹侧海马和内侧前额叶皮层局部场电位相位同步的变化,分析相位在工作记忆任务相关信息处理中的作用机制。研究数据为6只SD大鼠静息状态和执行Y迷宫空间工作记忆任务时采集的腹侧海马和内侧前额叶皮层的局部场电位信号,计算两个脑区局部场电位信号之间的加权相位滞后指数值。研究结果表明,与静息状态相比,在工作记忆编码阶段,腹侧海马和内侧前额叶皮层之间的相位同步性在theta频段选择性地显著增加。腹侧海马和内侧前额叶皮层theta频段的相位同步是工作记忆编码阶段任务信息处理的一个作用机制。 相似文献
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王淑珍 《西北大学学报(自然科学版)》2009,39(1):87-91
目的探讨焦虑个体\"热\"执行功能的情绪Stroop效应。方法采用情绪Stroop任务实验范式对筛选出的高、低特质焦虑被试（n=97）的\"热\"执行功能进行测量。结果两组被试的消极词汇Stroop效应量差异显著（P<0.05）,高焦虑组被试的消极词汇Stroop效应量显著小于低焦虑组;被试分类的主效应不显著（P>0.05）,词汇类型的主效应（积极词汇与消极词汇）显著（P<0.05）,词汇类型×被试分类的交互作用非常显著（P<0.01）;简单效应分析表明,被试的情绪Stroop效应量在消极词汇水平差异显著（P<0.05）,两类词汇的情绪Stroop效应量在低焦虑组差异非常显著（P<0.01）,在高焦虑组不显著（P>0.05）。结论焦虑个体的\"热\"执行功能下降,表现为焦虑个体的消极信息情绪Stroop效应反转,以及焦虑个体对消极信息的自动接近性与积极信息的回避性的倒置型热表征反应模式。 相似文献
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Kang Cheng 《自然科学进展(英文版)》2007,17(13):19-23
Among the many neuroimaging tools available for studying human brain functions, functional magnetic resonance imaging (fMRI) is the most widely used today. One advantage of fMRI over other imaging techniques is its relatively high spatial resolution. High-resolution fMRI, with its superb signal-to-noise ratio and improved tissue-vessel specificity, has strengthened the capability of fMRI and allowed mapping of fine cortical architectures in the human brain. In this review, I will first explain the factors limiting the spatial specificity of the blood oxygenation level-dependent (BOLD) effect, based on which most of fMRI experiments are conducted, and the measures dealing with these factors, and then briefly introduce several high-resolution (sub-millimeter) studies on the functional organization of human primary visual cortex (V1), including mapping of ocular dominance columns, mapping of temporal frequency dependent domains and direct demonstration of tuning to stimulus orientation. 相似文献
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Kang Cheng 《自然科学进展》2007,17(13):19-23
Among the many neuroimaging tools available for studying human brain functions, functional magnetic resonance imaging (fMRI) is the most widely used today. One advantage of fMRI over other imaging techniques is its relatively high spatial resolution. High-resolution fMRI, with its superb signal-to-noise ratio and improved tissue-vessel specificity, has strengthened the capability of fMRI and allowed mapping of fine cortical architectures in the human brain. In this review, I will first explain the factors limiting the spatial specificity of the blood oxygenation level-dependent (BOLD) effect, based on which most of fMRI experiments are conducted, and the measures dealing with these factors, and then briefly introduce several high-resolution (sub-millimeter) studies on the functional organization of human primary visual cortex (V1), including mapping of ocular dominance columns, mapping of temporal frequency dependent domains and direct demonstration of tuning to stimulus orientation. 相似文献