微量量热法研究细菌对头孢曲松钠和钩藤碱的耐药性

用瑞典Thenml Metric AB公司制造的新型微量量热仪(3114/3236 TAM Air)测定了不同浓度的头孢曲松钠、钩藤碱对大肠杆菌代谢作用的热功率一时间曲线,计算出细菌代谢的生长速率常数,建立了生长速率常数与药物浓度的关系,进而确定了最小抑菌浓度,在亚抑菌浓度下培养耐药菌,测出在亚抑菌浓度作用下的每一代耐药菌生长代谢的热功率一时间曲线,计算出每一代耐药菌的生长速率常数,建立了生长速率常数与传代次数之间的关系,进而得出了细菌对中西药耐药性的规律．     

中药石斛和雷公藤中的生物碱对大肠杆菌代谢作用的热动力学研究

从中药石斛、雷公藤中提取其中的生物碱，用瑞典产2277热活性检测仪测定了37℃下不同浓度的生物碱液对大肠杆菌代谢作用的热功率—时间曲线，计算出细菌生长的速率常数，建立了细菌生长速率常数与药物浓度之间的关系．结果表明，两种中药中的生物碱在一定浓度范围内对大肠杆菌有促进作用，并确定了最佳促菌浓度。     

微量量热法研究草乌生物碱对细菌的代谢作用

从草乌中提取生物碱，用瑞典产的2277型热活性检测仪测定了不同浓度的草乌生物碱液对大肠杆菌和金黄色葡萄球菌代谢作用的热功率－时间曲线，计算出细菌生长的速率常数，建立了速率常数与药物浓度间的关系，进而确定了最佳浓度。     

微量量热法筛选促菌特效营养药的研究

用热活性检测仪测定了枸杞、黄芪、灵芝、鹿茸对金黄色葡萄球菌促进作用的热功率—时间曲线;计算了不同浓度营养药物作用下的生长速率常数;根据生长速率常数和浓度的数据,确定了营养药物的最佳浓度.     

微量量热法筛选促菌特效营养药的研究

用热活性检测仪测定了枸杞,黄芪,灵芝,鹿茸对金黄色葡萄球菌促进作用的热功率－时间曲线,计算了不同浓度营养药物作用下的生长速率常数;根据生长速率常数和浓度的数据,确定了营养药物的最佳浓度。     

苯胺化合物双氧化活性与分子的电子结构

用量子化学MNDO方法研究苯胺化合物被微生物氧化为邻苯二酚化合物反应中，分子电子结构与氧化速率常数的相关性。由活性健MO能级，分子轨道中Pπ集居分布等指标，说明取代基在电子结构上对苯胺双氧化活性的影响。     

荷叶和黄藤中的生物碱对大肠杆菌代谢作用的微量量热法研究

从荷叶、黄藤中提取其中的生物碱,用瑞典产的2277型热活性检测仪测定了37℃下不同浓度的生物碱对大肠杆菌代谢作用的热功率-时间曲线,计算出细菌的生长速率常数,建立了生长速率常数与药物浓度之间的关系,进而确定了最佳用药浓度.     

皂甙抑菌作用的微量量热法研究

脑海微量量热计测定了四种细菌在不同浓度的皂甙药物作用下的生长热谱图，该药物对四种细菌生长有没程度的抑制作用，按指数生长模型进行数学处理，计算出生长速率常数，确定了临界生长用药浓度。     

β-环糊精与中性化合物结合常数的测定

在二元环湖精体系中采用毛细管电泳法测定了β-环糊精与中性化合物的结合常数．在磷酸盐缓冲溶液浓度10mM，硫酸化环糊精的浓度为2．5mM，pH为7．20的条件下，测得的β-环糊精与1-萘酚和2-萘酚的结合常数分别为80．50M^-1，720．99M^-1，519．00M^-1，并将比测定值与光谱法测定值进行了比较．结果表明，本文采用的方法快速可靠，适用于测定中性环糊精与中性化合物的结合常数．     

PLS和PM3算法对缺氧沉积物中卤代芳烃还原脱卤QSPR研究

运用Hamiltonian PM3算法，计算了36种卤代芳烃化合物的26个量子化学参数，在此基础上通过偏最小二乘法得到了卤代芳烃化合物在缺氟沉积物中还原脱卤速率的QSPR模型．该模型可用于解释卤代芳烃化合物还原脱卤的机理．结果表明，卤代芳烃化合物中整个分子的最负的原子净电荷(q^-)、键序最小的碳卤键中碳原子的单中心项电子—核吸引能(ENC)、该碳—卤键上碳原子的净电荷(qc)、分子最低未占据轨道能(EIumo)值越大，该卤代芳烃化合物还原脱卤的速率常数越小；而前线轨道间隙能(△E)、键序最小的碳卤键中碳原子的单中心项电子—电子推斥能(EEC)、相对分子质量(Mr)、整个分子的最正的原子净电荷(q^ )、平均分子极化率(α)值越大，该卤代芳烃化合物还原脱卤的速率常数越大．     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Density Functional Theory for the Response of Periodic Systems to Electric Fields Based on the Vector Potential Approach

正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that     

Call for Papers

<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with     

Journal of Donghua University ( English Edition) Contents of Volume 31

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Brief Introduction to “Journal of Jilin University( Science Edition) ”

<正>"Journal of Jilin University(Science Edition)"is a comprehensive academic journal in the fields of science sponsored by Jilin University and administrated by the Ministry of Education of the Peoples Republic of China.The journal started publication in 1955.The original name at starting publication was"Journal of Natural Science of Northeast People University",which was changed into"Acta Scientiarum Naturalium Universitatis Jilinensis"in 1958 owing to the name change of the university.The present journal name has