共查询到20条相似文献,搜索用时 15 毫秒
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Zusammenfassung Es wird gezeigt, dass Histamin auch durch das Aufreissen des Imidazolringes im Vormagen von Schafen katabolisiert werden kann. C14-markiertes Histamin wurde in den Pansen des Schafes oral eingeführt und annähernd 30% davon in der Atmungsluft (CO2) aufgefangen. 相似文献
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C. E. Constantinou 《Cellular and molecular life sciences : CMLS》1979,35(6):791-792
Summary An optical detection method, using video imaging, is used to quantitatively record the frequency and velocity profile of the renal pelvis of the rabbit. It is demonstrated that concentric waves originating at the periphery of the pelvis have an initial velocity of 3.2 cm/sec, accelerating toward the pelviureteral junction reaching a final velocity of 6.4 cm/sec.This work was supported by an NIH, grant No. AM 19366. 相似文献
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C E Constantinou 《Experientia》1979,35(6):791-792
An optical detection method, using video imaging, is used to quantitatively record the frequency and velocity profile of the renal pelvis of the rabbit. It is demonstrated that concentric waves originating at the periphery of the pelvis have an initial velocity of 3.2 cm/sec, accelerating toward the pelviureteral junction reaching a final velocity of 6.4 cm/sec. 相似文献
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J. P. Horwitz L. Horn A. V. Loud S. C. Brooks 《Cellular and molecular life sciences : CMLS》1962,18(9):414-416
Zusammenfassung Die Inkubation von 16-C14-Oestron und 4-C14-Oestradiol--acetat in Puffer (pH 7.4) bei Gegenwart von Rattenleber ergibt elektrophoretisch zwei deutliche radioaktive Bänder. Das erste Band entsteht im Albuminbereich und stimmt mit den früheren Beobachtungen vonSzego undRoberts
2 überein. Das zweite, früher nicht beschriebene Band entsteht deutlich ausserhalb des Albuminbereiches. Beide Kurvengipfel werden mit wenig homogenisierter Rattenleber, die möglichst frei von Mikrosomen ist, gewonnen. Der zweite Gipfelpunkt wird in diesem Fall der obenauf schwimmenden Phase zugeschrieben. 相似文献
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SANDRO CAPARRINI 《Archive for History of Exact Sciences》2002,56(2):151-181
(Received August 20, 2001) 相似文献
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Zusammenfassung Mikroelektrophoretisch verabreichtes Histamin, Histidin und Imidazolessigsäure hemmen die Aktivität von Neuronen der Medulla oblongata der Katze. Strychnin, welches in reversibler Weise die hemmende Wirkung von Glycin blockiert, zeigt keinen Antagonismus zu Imidazolessigsäure. 相似文献
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MSH, like traumata to the eye, cause a permeability disturbance in rabbits, with protein leakage into the aqueous. The MSH effect was enormously increased by instillation of imidazole or pilocarpine. The MSH effect seems to engage a different mechanism than the prostaglandin-dependent action of other agents. 相似文献
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CAPA peptides have been isolated from a broad range of insect species as well as an arachnid, and can be grouped into the
periviscerokinin and pyrokinin peptide families. In insects, CAPA peptides are the characteristic and most abundant neuropeptides
in the abdominal neurohemal system. In many species, CAPA peptides exert potent myotropic effects on different muscles such
as the heart. In others, including blood-sucking insects able to transmit serious diseases, CAPA peptides have strong diuretic
or anti-diuretic effects and thus are potentially of medical importance. CAPA peptides undergo cell-type-specific sorting
and packaging, and are the first insect neuropeptides shown to be differentially processed. In this review, we discuss the
current knowledge on the structure, distribution, receptors and physiological actions of the CAPA peptides.
Received 28 April 2006; received after revision 5 June 2006; accepted 4 July 2006 相似文献
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Waschek JA 《Cellular and molecular life sciences : CMLS》2004,61(18):2332-2342
The concept that atrial natriuretic peptide (ANP) and the closely related peptides BNP and CNP might be involved in the ontogeny of several organ systems emerged in the late 1980s. While many of the reported in vitro actions have not been examined in the context of organ development in vivo, recent studies demonstrate that mice which lack or overexpress natriuretic peptides or receptors exhibit pronounced skeletal growth defects. This article discusses how natriuretic peptides and other factors appear to regulate bone growth as an example of how natriuretic peptides might participate in the ontogeny of other organ systems. Evidence indicating that natriuretic peptides regulate neural development is then reviewed. Natriuretic peptides and receptors exhibit complex expression patterns in the developing nervous system, where they have been shown to act on neural cells as early as at the embryonic neural tube stage. Interestingly, both bone and brain growth appear to utilize primarily CNP and the CNP-specific type B receptor, and perhaps the type C receptor. In vitro data indicate that CNP may act on developing neurons, astrocytes and Schwann cells like a classical growth factor, regulating proliferation, patterning, phenotypic specification, survival and axonal pathfinding. Natriuretic peptides might also have roles in the vascularization of the embryonic brain, establishment of the blood-brain and blood-nerve barriers, and perhaps in nerve regeneration.Received 13 April 2004; received after revision 20 May 2004; accepted 27 May 2004 相似文献
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The trivalent lanthanide ions are chemically similar to Ca(II) ions, making them useful Ca analogs for a multitude of applications. In addition, Ln(III) ions are efficient catalysts of hydrolysis due to their much stronger Lewis acidity relative to Ca(II) ions. Ln-binding peptides thus offer both the opportunity to study known Ca sites as well as to explore new biological functions with an entire family of spectroscopically rich and reactive ions. This review discusses Ln-binding peptides in three roles: (i) as models of Ca-protein structure and function, (ii) as spectroscopic tags for protein expression and characterization and (iii) as designed artificial endonucleases. The creation of hydrolytically active Ln peptides that can fold, bind, cleave and discriminate among substrates shows that the design of Ln enzymes can be accomplished, and they will serve as versatile biochemical tools to investigate protein folding, structure and nuclease function.Received 10 April 2004; received after revision 17 May 2004; accepted 28 May 2004 相似文献