Effect of methyl palmitate on the survival of skin semi-allografts in rats

Summary In experiments with rats, the immunosuppressive effect of methyl palmitate on survival of skin semiallografts was proved. Methyl palmitate was applied in a single dose 1 day prior to transplantation.     

Effect of lindane on the skin of albino rats

Zusammenfassung Langfristig wiederholte Lindan-Applikation ruft bei der Abinoratte histopathologische hautveränderungen hervor: Hyperkeratinisation, intraepidermale und dermale Abszesse, Infiltration polymorphkerniger Zellen sowie Vakuolisation und Vielkernigkeit in der Malpighi-Schicht.

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Pury -isomer of 1,2,3,4,5,6-hexachlorocyclohexane.     

Effect of methyl amphetamine on the brain 5-hydroxytryptamine content of isolated and aggregated rats

Zusammenfassung Amphetamin bewirkt eine Vermehrung von 5-Hydroxytryptamin im Gehirn von aggregierten Ratten, während Chlorpromazin diesen Effekt hemmt.     

Effect of acetylsalicylate on surgical bleeding, postoperative mortality and allograft survival in rats undergoing heart transplantation.

18 rats were treated with L-ASA before heart transplantation and daily thereafter until death or rejection. 22 animals acted as controls. A significantly higher post-operative mortality rate, without any significant modification of the transplant survival time, was found in L-ASA-treated group.     

Daunomycin and skin allografts survival in mice

Riassunto L'effetto immunodepressivo della Daunomicina è stato studiato sulla sopravvivenza del trapianto cutaneo nel topo. La Daunomicina détermina un aumento del tempo di sopravvivenza del trapianto cutaneo, statisticamente significativo. Gli AA. discutono l'importanza che possono assumere le dosi, la via di somministrazione e lo schema di trattamento impiegato.     

Autoantibody formation against spleen in rats ‘chemically splenectomized’ by ethyl palmitate

Summary The follow-up experiments with rats revealed auto-antibodies against spleens damaged by an i.v. ethyl palmitate injection. The antibodies could be shown in some animals only.     

Effect of parathion on the skin of guinea-pigs

Zusammenfassung Nach täglicher Applikation of Parathion werden histologisch Veränderungen der Meerschweinchenhaut festgestellt.     

Prolongation of the survival of skin grafts in mice by PUVA treatment

Summary The combined application of psoralen and UVA radiation to skin grafts induced a prolongation of the survival time of the grafts in mice. This was observed using the H-Y barrier, an allogeneic barrier without H-2 disparities, and a strong H-2 incompatible barrier. The effect is probably due to a reduction of antigen-presenting cells, or to other, unknown mechanisms.     

Prolongation of the survival of skin grafts in mice by PUVA treatment

The combined application of psoralen and UVA radiation to skin grafts induced a prolongation of the survival time of the grafts in mice. This was observed using the H-Y barrier, an allogeneic barrier without H-2 disparities, and a strong H-2 incompatible barrier. The effect is probably due to a reduction of antigen-presenting cells, or to other, unknown mechanisms.     

Therapy of chemically induced skin tumors of mice with vitamin a palmitate and vitamin a acid

Zusammenfassung Mittels Dimethylbenzanthracen und Krotonöl wurden bei Mäusen Hautpapillome erzegut. Diese Tumoren wurden durch systemische Anwendung von Retinylpalmitat und Retinsäure therapeutisch beeinflusst. Es kam zu einer deutlichen Regression der Tumoren, die dosisabhängig war. Sowohl orale wie parenterale tägliche oder wöchentliche Applikation der geprüften Vitamin-A-Verbindungen waren wirksam. Der Wirkungsamechanismus wird diskutiert. Er unterscheidet sich grundsätzlich von demjenigen anderer tumorhemmender Substanzen.