高超声速飞行器准平衡滑翔自适应制导方法

针对高超声速飞行器同时满足终端约束及过程约束的再入滑翔制导问题,提出了一种全新的准平衡滑翔自适应制导方法．该方法充分利用升力式再入飞行中的准平衡滑翔现象,并以准平衡滑翔条件（QEGC）为核心,一方面,利用QEGC的特定弹道形式实现对终端速度及射程的精确解析预测;另一方面,借助QEGC将传统预测类制导方法难以处理的飞行过程约束转化为攻角约束．该算法不依赖于标准轨迹,实现了制导指令倾侧角及攻角均采用解析公式实时解算,使制导方法具备了自适应能力．CAV-H飞行器制导实例仿真表明,该制导方法能够导引飞行器平衡滑翔飞行,满足终端约束和过程约束,并且对任务临时改变具有自适应性．该制导方法的鲁棒性通过Monte Carlo仿真得到验证．     

A novel method in enzyme immunoassay: Maleimide derivative of hapten for enzyme coupling

Summary Meta-maleimidobenzoyl derivative of L-thyroxine methyl ester (MBTM) was synthesized and coupled to -galactosidase at molar ratio of over 5 to 1. More than 97% of the enzyme was found to be labeled with MBTM. A thyroxine enzyme immunoassay was carried out with sensitivity in the 0–10 g/100 ml range.     

A novel method in enzyme immunoassay: maleimide derivative of hapten for enzyme coupling.

Meta-maleimidobenzoyl derivative of L-thyroxine methyl ester (MBTM) was synthesized and coupled to beta-galactosidase at molar ratio of over 5 to 1. More than 97% of the enzyme was found to be labeled with MBTM. A thyroxine enzyme immunoassay was carried out with sensitivity in 0-10 microgram/100 ml range.     

Maternal behavior in two rat lines selected for differences in the acquisition of two-way avoidance

Summary The maternal behavior of Roman high- and low-avoidance (RHA/Verh and RLA/Verh) rats was studied, using a time-sampling method. It was concluded that: a) RLA/Verh mothers spent more time with their young, b) RHA/Verh mothers were more active, and c) the mothers of both lines mostly blanketed their young during nursing, although the RHA/Verh mothers assumed the side-nursing position more often than their counterparts.This work was partly supported by a research grant from the Swiss Association of Cigarette Manufacturers. Reprint reqyests should be addressed to P. Driscoll at the given address.     

Maternal behavior in two rat lines selected for differences in the acquisition of two-way avoidance.

The maternal behavior of Roman high- and low-avoidance (RHA/Verh and RLA/Verh) rats was studied, using a time-sampling method. It was concluded that: a)RLA/Verh mothers spent more time with their young, b) RHA/Verh mothers were more active, and c) the mothers of both lines mostly "blanketed' their young during nursing, although the RHA/Verh mothers assumed the side-nursing position more often than their counterparts.     

非对称双向中继X网络中基于最大化和速率的干扰对齐与中继处理算法

双向中继X网络相对于传统无线通信网络可以实现更高的自由度.然而,基于迫零算法的中继处理算法仅考虑了消除干扰成分,忽略了对期望信号的影响,从而使得网络的和速率有待提高.特别地,当用户发送功率越低,其和速率劣势越明显.针对上述问题研究其干扰对齐方案,并给出了优化的联合考虑期望信号和干扰信号的中继处理算法.首先,通过利用用户矢量信号之间的空间关系,给出网络和速率的数学模型;其次,通过矩阵分析及数值分析理论将最大化网络和速率的中继预编码设计问题转化为线性搜索最优值问题,并用极限值方法近似网络目标函数;再次,进一步将双向网络的目标函数近似为单向网络用户参数的线性组合,大大降低算法复杂度;最后,基于优化的线性搜索最优值问题,得到最大化网络和速率的中继预编码矩阵.仿真结果表明:相较于现有的中继处理方案,本文方案明显改善了网络和速率,同时还简化了最大化网络和速率带来的算法复杂度.     

Using genetically-defined rodent strains for the identification of hippocampal traits relevant for two-way avoidance behavior: a non-invasive approach

Genetically-defined rodent strains permit the identification of hippocampal traits which are of functional relevance for the performance of two-way avoidance behavior. This is exemplified here by analyzing the relationship between infrapyramidal mossy fibers (a tiny projection terminating upon the basal dendrites of hippocampal pyramidal neurons) and two-way avoidance learning in about 800 animals. The necessary steps include 1) identification of structural traits sensitive to selective breeding for extremes in two-way avoidance, 2) testing the robustness of the associations found by studying individual and genetical correlations between hippocampal traits and behavior, 3) establishing causal relationships by Mendelian crossing of strains with extreme structural traits and studying the behavioral consequences of such structural 'randomization', 4) confirming causal relationships by manipulating the structural variable in inbred (isogenic) strains, thereby eliminating the possibility of genetic linkage, and 5) ruling out the possibility of spurious associations by studying the correlations between the hippocampal trait and other behaviors known to depend on hippocampal functioning. In comparison with the classical lesion approach for identifying relationships between brain and behavior, the present procedure appears to be superior in two aspects: it is non-invasive, and it focuses automatically on those brain traits which are used by natural selection to shape behaviorally-defined animal populations, i.e., it reveals the natural regulators of behavior.     

Equilibrium equations for nonlinear buckling analysis of drill-strings in 3D curved well-bores

With the development of drilling technology,the oil/gas well has evolved from its early vertical straight form to the inclined,horizontal,plane curved,or even 3D curved well-bore.Understanding of the buckling behavior of a drill-string in a well-bore is crucial for the success of a drilling operation.Therefore,equilibrium equations for analyzing the buckling behavior of a drill-string in a 3D curved well-bore are required.Based on Love's equilibrium equations for a curved and twisted rod in space,a set of e...     

Using genetically-defined rodent strains for the identification of hippocampal traits relevant for two-way avoidance behavior: a non-invasive approach

Summary Genetically-defined rodent strains permit the identification of hippocampal traits which are of functional relevance for the performance of two-way avoidance behavior. This is exemplified here by analyzing the relationship between infrapyramidal mossy fibers (a tiny projection terminating upon the basal dendrites of hippocampal pyramidal neurons) and two-way avoidance learning in about 800 animals. The necessary steps include 1) identification of structural traits sensitive to selective breeding for extremes in two-way avoidance, 2) testing the robustness of the associations found by studying individual and genetical correlations between hippocampal traits and behavior, 3) establishing causal relationships by Mendelian crossing of strains with extreme structural traits and studying the behavioral consequences of such structural randomization, 4) confirming causal relationships by manipulating the structural variable in inbred (isogenic) strains, thereby eliminating the possibility of genetic linkage, and 5) ruling out the possibility of spurious associations by studying the correlations between the hippocampal trait and other behaviors known to depend on hippocampal functioning.In comparison with the classical lesion approach for identifying relationships between brain and behavior, the present procedure appears to be superior in two aspects: it is non-invasive, and it focuses automatically on those brain traits which are used by natural selection to shape behaviorally-defined animal populations, i.e., it reveals the natural regulators of behavior.     

Synthesis of maleimide derivative of cortisol for enzyme coupling in cortisol enzyme immunoassay

Summary A new cortisol derivative, cortisol-21-m-maleimidobenzoate (CMB), was synthesized and conjugated with sulfhydryl groups of -galactosidase (BG). Both CMB-BG and CHS-BG conjugates have a high immunoreactivity to cortisol antibody, and although CHS-BG does not displace well with the added cortisol, CMB-BG does.Acknowledgments. This work was supported in part by Grant 884M from the Council for Tobacco Research. We wish to thank Miss Laura Morbach and Mrs Tatsue Monji for their assistance on this project.Address reprint requests to A. Castro.