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Hilt W 《Cellular and molecular life sciences : CMLS》2004,61(13):1615-1632
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Antisense transcription: A critical look in both directions 总被引:3,自引:1,他引:2
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DNA damage repair and transcription 总被引:2,自引:0,他引:2
Berardi P Russell M El-Osta A Riabowol K 《Cellular and molecular life sciences : CMLS》2004,61(17):2173-2180
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Protecting against promiscuity: the regulatory role of insulators 总被引:11,自引:0,他引:11
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DNA methylation and the regulation of gene transcription 总被引:28,自引:0,他引:28
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Poly-ADP-ribosylation in health and disease 总被引:6,自引:0,他引:6
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Physiological significance of STAT proteins: investigations through gene disruption in vivo 总被引:7,自引:0,他引:7
D. E. Levy 《Cellular and molecular life sciences : CMLS》1999,55(12):1559-1567
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Anne Berna François Bernier Eric Chabrière Mikael Elias Ken Scott Andrew Suh 《Cellular and molecular life sciences : CMLS》2009,66(14):2205-2218
DING proteins, identified mainly by their eponymous N-terminal sequences, are ubiquitous in living organisms. Amongst bacteria,
they are common in pseudomonads, and have been characterised with respect to genetics and structure. They form part of a wider
family of phosphate-binding proteins, with emerging roles in phosphate acquisition and pathogenicity. Many DING proteins have
been isolated in eukaryotes, in which they have been associated with very diverse biological activities, often in the context
of possible signalling roles. Disease states in which DING proteins have been implicated include rheumatoid arthritis, lithiasis,
atherosclerosis, some tumours and tumour-associated cachexia, and bacterial and viral adherence. Complete genetic and structural
characterisation of eukaryotic DING genes and proteins is still lacking, though the phosphate-binding site seems to be conserved.
Whether as bacterial proteins related to bacterial pathogenicity, or as eukaryotic components of biochemical signalling systems,
DING proteins require further study.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. 相似文献
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Biological functions of the ING family tumor suppressors 总被引:11,自引:0,他引:11