基于云平台的医学影像可视交互平台

针对传统医学影像可视化软件难以实现跨平台访问,以及有限的影像数据的存储和体绘制能力,且缺少协同可视化共享的机制,本文提出一个基于云平台的医学影像可视化平台.利用云平台超大的存储容量以及强大的图形图像处理能力,在云端进行医学图像的编解码、分割及高级体绘制,然后本文提出支持协同可视化的自适应医学元数据和图像数据传输协议,通过浏览器和云端的实时交互以及浏览器和浏览器的对等传输,实现了影像的各种二维和三维协同可视化交互功能.实验结果表明,我们的平台不仅能以协同方式支持大容量数据的二维实时浏览和伪彩映射,而且支持三维的高级分割和体绘制操作,并且有较好的实时交互性.     

全球3D生物打印技术研究态势分析

本文以Web of Science核心合集数据库为统计源,对该数据库收录的3D生物打印技术的文章进行文献计量学分析,利用德温特数据分析软件(Derwent Data Analyzer,DDA)和VOSviewer可视化软件,对全球3D生物打印技术领域发展态势进行分析.Web of Science核心合集数据库收录3D生...     

PDMiner:基于云计算的并行分布式数据挖掘工具平台

随着信息技术和互联网的发展,各种信息呈现爆炸性增长,且包含丰富的知识.从海量数据信息中挖掘得到有用的知识仍然是一个挑战性的课题.近几十年来,数据挖掘技术,作为从海量数据信息中挖掘有用信息的关键技术已经引起了广泛的兴趣和研究.但是由于数据规模的增长,以往的很多研究工作并不能有效地处理大规模数据,因此,开发设计或者扩展已有算法使之能处理大规模数据集,已经成为数据挖掘中非常重要的研究课题.近年来,基于云计算的数据挖掘技术研究已经成为一个热点话题,本文中我们研究开发一个基于大规模数据处理平台Hadoop的并行分布式数据挖掘工具平台PDMiner.在PDMiner中,开发实现了各种并行数据挖掘算法,比如数据预处理、关联规则分析以及分类、聚类等算法.实验结果表明,并行分布式数据挖掘工具平台PDMiner中实现的并行算法:1)能够处理大规模数据集,达到TB级别;2)具有很好的加速比性能;3)大大整合利用已有的计算资源,因为这些算法可以在由这些商用机器构建的并行平台上稳定运行,提高了计算资源的利用效率;4)可以有效地应用到实际海量数据挖掘中.此外,在PDMiner中还开发了工作流子系统,提供友好统一的接口界面方便用户定义数据挖掘任务.更重要的是,我们开放了灵活的接口方便用户开发集成新的并行数据挖掘算法.     

机载雷达Doppler分布式杂波模型及参数估计

针对机载雷达平台运动造成的杂波谱中心偏移和展宽, 提出一种Doppler分布式杂波(DDC)模型在时域描述杂波协方差矩阵. 并基于该参数化模型, 研究了最大似然、加权子空间匹配等超分辨率方法在杂波Doppler参数估计中的应用, 取得了明显优于传统方法的性能. 理论推导和实际数据处理结果也验证了模型的正确性及参数估计方法的有效性.     

基于VDM的复杂装备故障数据分析

在历史故障数据基础上,分别掏建故障信息、装备信息、装备使用状况的数据集市,通过数据挖掘模型和可视化交互平台,形成基于可视化数据挖掘（Visual Data Mining,VDM）故障分析架构。以此架构为基础,探讨了故障数据仓库的建立以及故障数据挖掘算法,对实际故障数据进行预处理,并分析故障责任、故障趋势、故障分布等特性,得到图形化的分析结论,为装备的设计、制造、维护提供支持。     

面向云-端融合的移动互联网应用运行平台

与传统的互联网应用相比,移动互联网应用尽管也运行于Web技术栈之上,但移动设备的便携性和多样性,带来了客户端设备计算能力相对有限、数据存储随需而变、显示屏幕大小不一、本地应用与Web应用和服务难以交互等技术挑战．为此,本文设计实现了一种面向云一端融合的移动互联网应用运行平台．首先,提出一种符合移动互联网应用体系结构的构件模型,将客户端应用划分为数据、计算、界面和服务四个部分;其次,设计了一种实现云一端资源融合的构件运行框架,支持应用数据的按需存储、计算任务的云端迁移、以及用户界面的动态切分;再次,设计了一种实现云一端服务融合的组装框架,支持客户端本地应用和传统Web应用的服务封装、和基于总线的服务即时组装;最后,基于Chrome浏览器实现了平台原型,支持基于HTML5和JavaScript的移动互联网应用,通过多个Web应用基准测试集和热点应用的实验,验证了平台的有效性和可行性．     

国内外医疗数据可视化研究的现状分析与展望

本文利用科学计量学和知识图谱的方法展示了2010—2019这十年国内外医疗数据可视化研究的分布及主题特点,分析国内外相关研究的共性、对比二者的主要差异,从中挖掘目前国内医疗数据可视化研究存在的问题并提出应对建议。这十年国内外医疗数据可视化领域文献年发文量呈逐年增长趋势,其中后五年国内相关研究数量呈指数增长,国内外对医疗数据可视化研究的重视程度均有所提高,但当前国内相关研究较国外研究相比存在起步晚、科研主题创新和活力不足、研究主题粒度较大不够细化、处理数据来源和应用范围有局限性、可视化研究成果形式不够丰富等实际问题。本研究对这些突出问题逐一列举并提出解决建议,以期为未来医疗数据可视化研究的学者提供借鉴和参考,助力大数据时代医疗数据资源在可视化层面的高效利用。     

大坝安全网络监控数据采集系统的设计

介绍一种基于分布式结构的大坝安全网络监控数据采集系统系统分别利用RS-485网络和以太网与下层测量仪器和上层的监控主机连接,采用分布式结构以及组网方式,实现大坝安全网络监测自动化软件对整个大坝形态进行实时监控.重点研究数据采集器的工作原理、硬件构成以及上位机监测软件的设计与实现.该系统能够有效满足大坝远程通信和监控的要求并已成功运用于大坝安全监测领域.     

利用内点法优化三相不平衡分布式电网的理论算法研究

目前分布式电网的潮流优化算法主要面对三相功率平衡系统,对于三相不平衡系统进行分析的算法介绍较少.文中利用内点法,结合美国电科院的开放式配电仿真系统分析(OpenDSS)平台,提出了三相不平衡分布式电网潮流优化算法的研究.该算法以网损和变压器三相潮流不平衡度最小为目标,以系统潮流、发电机和线路极限容量为约束,以变压器分接头和电容器投切为控制变量,建立了优化函数,利用内点法作为优化算法,以 OpenDSS为计算平台.文中最后以 IEEE123测试节点和 IEEE9500测试节点为例,验证了文中算法的有效性和实用性     

基于多活性代理的分布式入侵检测系统构建分析研究

针对应用了移动代理技术的分布式入侵检测系统在代理安全性和稳定性方面所存在的问题,本文在基于多活性代理复杂信息系统研究方法的指导下,提出了一种新的分布式入侵检测系统结构,即基于多活性代理的分布式入侵检测系统(DIDS-MLA).该系统将传统分布式入侵检测系统的两层结构扩展为三层结构,通过增加的一层结构对系统中各个检测代理活性状态值进行监测,使系统能够在多活性代理协商协调机理的指导下,根据代理活性状态值的变化来调整各代理的工作,从而达到保护系统中代理安全性以及维护系统检测稳定性的目的.在之前的研究工作中,我们仅仅对活性代理进行了定性分析,本文中则进一步提出了一种在分布式入侵检测环境下定量分析代理活性的方法,并在此基础上给出了系统中活性代理的实现思路.最后通过对系统工作流程以及对分布式拒绝服务攻击的检测效果进行分析之后,我们可以看出,本文所设计的DIDS-MLA系统在安全性和稳定性方面比传统分布式入侵检测系统(DIDS)以及基于移动代理的DIDS系统有明显改善,能够在强对抗环境下保证系统检测工作的正常运行.     

Inherent properties and statistics with individual particles in quantum mechanics

This paper puts forward the hypothesis that the distinctive features of quantum statistics are exclusively determined by the nature of the properties it describes. In particular, all statistically relevant properties of identical quantum particles in many-particle systems are conjectured to be irreducible, ‘inherent’ properties only belonging to the whole system. This allows one to explain quantum statistics without endorsing the ‘Received View’ that particles are non-individuals, or postulating that quantum systems obey peculiar probability distributions, or assuming that there are primitive restrictions on the range of states accessible to such systems. With this, the need for an unambiguously metaphysical explanation of certain physical facts is acknowledged and satisfied.     

Spasmin-like proteins in various ciliates revealed by antibody to purified spasmins ofCarchesium polypinum

Summary It was found that some ciliates,Stentor, Spirostomum andBlepharisma, which can contract rapidly like the stalks of Vorticellidae, have Ca²⁺-binding proteins that are very similar to spasmins, in the immunological sense. The presence of spasmins in other Protozoa and in some Metazoa was also investigated.     

Partial sequence of the gene for a serine protease from a halophilic archaeumhaloferax mediterranei R4, and nucleotide sequences of 16S rRNA encoding genes from several halophilic archaea

A part of the gene coding for a halophilic serine protease from a halophilic archaeumHaloferax mediterranei R4 was amplified by PCR and its 672 nucleotide sequence was determined. Tentative translation to the amino acid sequence suggested that the enzyme was quite similar to halolysin produced by another halophilic archaeum strain 172P1. Nucleotide sequences of 16S rRNA encoding genes from 9 halophilic archaea were determined. Alignment of 19 sequences known so far showed that there are more than 20 positions carrying bases or deletions specific for each halobacterial genus:Halobacterium, Haloarcula, Haloferax, andHalococcus.     

Endorcine cells producing regulatory peptides

Summary Recent data on the immunologication of regulatory peptides and related propeptide sequences in endocrine cells and tumours of the gastrointestinal tract pancreas, lung, thyroid, pituitary (ACTH and opioids), adrenals and paraganglia have been revised and discussed. Gastrin, xenopsin, cholecystokinin (CCK), somatostatin, motilin, secretin, GIP (gastric inhibitory beenrevised and discussed. Gastrin, xenopsin, cholecystokinin (CCK), somatostatin, motilin, secretin, GIP (gastric inhibitory polypeptide), neurotensin, glicentin/glucagon-37 and PYY (peptide tyrosine tyrosine) are the main products of gastrointestinal endocrine cells; glucagon, CRF (corticotropin releasing factor), somatostatin, PP (pancreatic polypeptide) and GRF (growth hormone releasing factor), in addition to insulin, are produced in pancreatic islet cells; bombesin-related peptidesare the main markers of pulmonary endocrine cells; calcitonin and CGRP (calcitonin gene-related peptide) occur in thyroid and extrathyroid C cells; ACTH and endorphins in anterior and intermediate lobe pituitary cells, -MSH and CLIP (corticotropoin-like intermediate lobe peptide) in intermediate lobe cells; met- and leu-enkephalins and related peptides in adrenal medullary and paraganglionic cells as well as in some gut (enterochromaffin) cells; NPY (neuropeptide Y) in adrenalin-type adrenal medullary cells, etc.. Both tissue-appropriate and tissue-inappropriate regulatory peptides are produced by endocrine tumours, with inappropriate peptides mostly produced by malignant tumours.     

Cognition wars

In what kinds of physical systems can cognition be realized? There are currently competing answers among scientists and theorists of cognition. There are many plant scientists who maintain that cognition can be realized in plants. There are biological scientists who maintain that cognition is materially realized in bacteria. In this paper, I will present the basis for such claims and evaluate them and discuss the future for theories of the metaphysical basis of cognition in the cognitive sciences.     

Anthelmintic activity of a benzimidazoline compound in sheep by abomasal infusion

Summary In vitro and in vivo data on the benzimidazoline compound indicate anthelmintic potential when introduced directly into the abomasum.     

Evolutionary and ecological implications of cardenolide sequestration in the monarch butterfly

Summary Monarch butterflies sequester cardenolides from their larval host plants in the milkweed genusAsclepias for use in defense against predation. Of 108Asclepias species in North America, monarchs are known to feed as larvae on 27. Research on 11 of these has shown that monarchs sequester cardenolides most effectively, to an asymptote of approximately 350 g/0.1 g dry butterfly, from plants with intermediate cardenolide contents rather than from those with very high or very low cardenolide contents. SinceAsclepias host plant species are distributed widely in space and time across the continent, monarchs exploit them by migration between breeding and overwintering areas. After overwintering in central Mexico, spring migrants east of the Rocky Mountains exploit three predominantAsclepias species in the southern USA that have moderately high cardenolide contents. Monarchs sequester cardenolides very effectively from these species. First generation butterflies are thus well protected against predators and continue the migration north. Across the northern USA and southern Canada most summer breeding occurs on a fourthAsclepias species and in autumn most of these monarchs migrate back to Mexican overwintering sites. The ecological implications of this cycle of cardenolide sequestration for the evolution of monarch migration are discussed.     

Bioaccumulation processes in ecosystems

The fate of environmental pollutants — the various isotopes of elements, and inorganic or organic compounds — is a fundamental aspect of ecology and ecotoxicology, and bioaccumulation is a phenomenon often discussed in this context. Human activities have drastically altered natural concentrations of many substances in the environment and added numerous new chemicals. An understanding of the processes of bioaccumulation is important for several reasons. 1) Bioaccumulation in organisms may enhance the persistence of industrial chemicals in the ecosystem as a whole, since they can be fixed in the tissues of organisms. 2) Stored chemicals are not exposed to direct physical, chemical, or biochemical degradation. 3) Stored chemicals can directly affect an individual's health. 4) Predators of those organisms that have bioaccumulated harmful substances may be endangered by food chain effects. While former theories on the processes of bioaccumulation focused on single aspects that affect the extent of accumulation (such as the trophic level within the food chain or the lipophilicity of the chemical), modern theories are based on compartmental kinetics and the integration of various environmental interactions. Concepts include results from quantitative structure-activity relationships (QSAR), pharmacokinetics, ecophysiology and general biology, molecular genetic aspects and selection, and finally the structure of communities and man-made alterations in them.     

Mating attempts between the Scarlet Tiger Moth,Callimorpha dominula L., and the Cinnabar Moth,Tyria jacobaeae L. (Lepidoptera: Arctiidae), involve a common sex pheromone composition

It has been suggested that a common sex pheromone composition may account for interspecific sexual interactions observed with certain moths in the Arctiidae. In this study, it is demonstrated that the sex pheromones released by females of the Scarlet Tiger Moth,Callimorpha dominula L., and the Cinnabar Moth,Tyria jacobaeae L., have similar activities and elute at the same retention time on analysis by coupled gas chromatography (GC)-electrophysiology with males from each species. Peak enhancement on GC, chiral GC and coupled GC-mass spectrometry using authentic compounds show that the sex pheromone for bothC. dominula andT. jacobaeae is (3Z,6Z,9S,10R)-9,10-epoxyheneicosa-3,6-diene.     

Phenology of fruit and leaf production by ‘strangler’ figs on Barro Colorado Island,Panamá

Summary Fruit and leaf initiation by 26 trees representing five stranglerFicus species in the subgenusUrostigma were monitored for 5–8 years in a seasonal lowland forest of central Panamá. Individual trees of each species initiated fruit in synchronized crops. High variation in the number of crops, intervals between crops and dates of crop initiation indicate that these species, like species in the subgenusPharmacosycea, initiate fruit crops the year around. Nevertheless, mean crop initiation dates for four of five species fell within the four-month dry season. Similarly, all species produced new leaf flushes throughout the year, however, mean leaf flush dates of all species fell within the first three months of the dry season.