共查询到20条相似文献,搜索用时 15 毫秒
1.
Summary It was found that the MPG partially protects the spleen against weight loss due to radiation, and exaggerates the compensatory reaction in the tissue during recovery. It is also concluded that MPG protects the stem cells in the spleen, which helps to restore the peripheral blood by extramedullary erythropoiesis. 相似文献
2.
P. K. Dev S. M. Gupta P. K. Goyal G. Mehta B. P. Pareek 《Cellular and molecular life sciences : CMLS》1982,38(8):962-963
Summary 2-Mercaptopropionylglycine administered during fetal growth period, protected significantly young mice against loss of body weight during postnatal development induced by 50 R gamma irradiation.Acknowledgment. The work was supported by a grant from CSIR, New Delhi, to P.K.D. which is gratefully acknowledged. The authors are also thankful to Prof. P. Navlakha for the irradiation facilities. 相似文献
3.
Summary MPG, administered in utero against I131-irradiation, protected young mice to some extent from loss of body weight at different postnatal intervals. Increase in the tissue weight induced by the internal emitter was enhanced at 6 weeks of age by the drug.Acknowledgment. This work was supported by a grant from the University Grants Commission, New Delhi, to Dr P.K. Dev and the same is gratefully acknowledged. 相似文献
4.
Summary External irradiation resulted in an increase in thyroid131I uptake and plasma PB131I conversion ratio, whereas pretreatment with MPG reduced both the values significantly. Metabolic inhibition is suggested as a possible mechanism of action by the drug.Acknowledgment. The financial support from the CSIR, India, in the form of a research grant is gratefully acknowledged. Our thanks are also due to Prof. P. Navalkha, Radiotherapy Unit, SMS Hospital, Jaipur, for providing irradiation facilities. 相似文献
5.
Summary The pronormoblasts and normoblasts in Swiss albino mice were found to be very sensitive to radiation and their percentage was reduced drastically after exposure to gamma-rays. The degree of damage increased with increase in radiation dose. MPG reduced the initial damage and brought about an early and fast recovery. It is concluded that the drug protects the stem cells and thereby reduces the depletion of the regenerating pool which causes a more efficient and accelerated recovery. 相似文献
6.
M. R. Saini P. Uma Devi S. S. Yadav 《Cellular and molecular life sciences : CMLS》1978,34(12):1627-1628
Summary The drug, MPG, when administered before irradiation, increases the radioresistance of bone marrow lymphocytes of mice to gamma rays and helps in promoting fast recovery, especially when exposed to sublethal dose. 相似文献
7.
8.
It has been recently reported that the levo isomer of propranolol possesses anti-serotonin properties in animals. Since harmine-induced behavioural changes in mice are reported to be mediated through central serotonergic receptors, an attempt was made to test whether 1-propranolol would also modify harmine-induced responses by virtue of its anti-serotonergic or anti-adrenergic property. The results indicated that l- and dl-propranolol inhibited central serotonin receptor mediated responses to harmine in mice, a finding that is analogous to other recent observations. 相似文献
9.
Summary It has been recently reported that the levo isomer of propranolol possesses anti-serotonin properties in animals. Since harmine-induced behavioural changes in mice are reported to be mediated through central serotonergic receptors, an attempt was made to test whether 1-propranolol would also modify harmine-induced responses by virtue of its antiserotonergic or anti-adrenergic property. The results indicated that 1- and dl-propranolol inhibited central serotonin receptor mediated responses to harmine in mice, a finding that is analogous to other recent observations. 相似文献
10.
Summary The radiosensitivity of primary spermatocytes in pachytene stage was estimated by counting the number of spermatids in the testes of control and MPG-treated mouse after exposure to 500, 1000 and 1500 R of Co60 gammarays. For this purpose, control and MPG-treated mice were killed 5 days after irradiation and countings of spermatids was made in stages I and II of the tubules. It has been observed that, although there was a death of primary spermatocytes in irradiated MPG-protected groups, quantitatively significant protection was afforded by this drug at all the 3 dose-levels studied. 相似文献
11.
The radiosensitivity of primary spermatocytes in pachytene stage was estimated by counting the number of spermatids in the testes of control and MPG-treated mouse after exposure to 500, 1000 and 1500 R of Co60 gamma-rays. For this purpose, control and MPG-treated mice were killed 5 days after irradiation and countings of spermatids was made in stages I and II of the tubules. It has been observed that, although there was a death of primary spermatocytes in irradiated MPG-protected groups, quantitatively significant protection was afforded by this drug at all the 3 dose-levels studied. 相似文献
12.
13.
M. Jakóbisiak M. Kamiński A. E. Kossakowska T. Rymaszewska-Kossakowska 《Cellular and molecular life sciences : CMLS》1973,29(3):335-336
Zusammenfassung Nachweis eines Hemmeffektes immunosupressiver Mittel (Cortison, Cyclophosphamide und Immuran) bei Mäusen nach UV-Bestrahlung auf die hämopoetische Regeneration (Milzkolonien und Knochenmarkzellen). 相似文献
14.
15.
R. I. Walker R. J. Moon P. F. Alm G. D. Ledney 《Cellular and molecular life sciences : CMLS》1976,32(12):1527-1529
Summary Oral antibiotic prophylaxis of mice, particularly those with radiation-induced injury or those undergoing GVHD, alters bactericidal activity of the host. 相似文献
16.
17.
18.
Monospecific antibody plaque formation by spleen cells from mice immunized with sheep and chicken erythrocytes 总被引:1,自引:0,他引:1
H Friedman 《Experientia》1964,20(10):564-565
19.
H. Friedman 《Cellular and molecular life sciences : CMLS》1964,20(10):564-565
Zusammenfassung Milzzellenaufschwemmungen von Mäusen, die mit einem Gemisch von Schaf- und Hühnererythrocyten einmal injiziert wurden, verursachen lokalisierte, hämolytische Zonen (antibody plaques), die nicht aus den beiden Zelltypen, sondern entweder nur aus Schaf- oder nur aus Hühnerzellen bestehen. Lymphatische Zellen, die gleichzeitig zwei verschiedene Hämolysine abscheiden können, sind in Milzzellenaufschwemmungen von zweifach immunisierten Mäusen anscheinend abwesend oder nur in ganz geringer Anzahl vorhanden.
The capable technical assistance of Mrs.Leony Mills during these studies is acknowledged. This investigation was supported in part by the U.S. National Science Foundation (Grant G-19581). 相似文献
The capable technical assistance of Mrs.Leony Mills during these studies is acknowledged. This investigation was supported in part by the U.S. National Science Foundation (Grant G-19581). 相似文献