Monoacylcadaverines as substrates for both monoamine oxidase and diamine oxidase; low rates of activity

Summary Monoacetylcadaverine and monopropionylcadaverine were found to be substrates for both rat liver monoamine oxidase and hog kidney diamine oxidase, but all the K_m-values for the oxidases were very high. The amines were common substrates for type A and type B monoamine oxidase.     

Development of behavioural tolerance to nicotine in the rat

Résumé On a donné de la nicotine à des rats une fois par jour, pendant 10 jours. L'activité des animaux a d'abord diminué, mais après quelques administrations de la drogue, on constata une accoutumance à ces effets. L'administration terminée, l'activité a augmenté.

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This work was supported by a grant from the Tobacco Research Council.     

The interaction of angiotensin with a binding factor in plasma

Résumé La liaison de l'angiotensine par les protéines plasmatiques est démontrée par dialyse équilibrée. L'angiotensine radioactive liée ne put être déplacée par l'angiotensine non radioactive, ce qui diminue la signification physiologique de cette liaison.

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Supported in part by the Michigan Heart Association.     

Effect of food and light schedule on bile flow in the rat

Summary In the rat after food intake, whether during the dark or light period, bile flow increases. Food intake seems to be a major factor in the circadian rhythm of bile secretion.     

Effect of food and light schedule on bile flow in the rat

In the rat after food intake, whether during the dark or light period, bile flow increases. Food intake seems to be a major factor in the circadian rhythm of bile secretion.     

The interaction of a gibberellin and a kinin in the control of chlorophyll synthesis

Resumé La promtion synergétique et l'inhibition de la synthèse de la chlorophylle par la gibberelline (GA₃) et par la 6-benzylaminopurine (6-BAP) de concentrations diverses, fut observée. L'augmentation de la concentration de 6-BAP réduisit la concentration de GA₃ nécessaire pour obtenir la promotion maximum.     

Continuous registration of X,Y-coordinates and angular position in behavioural experiments

Summary An electronic camera and 2 simple additional circuits for the registration of the X, Y-coordinates or the angular position of animals in behavioural experiments are described.     

Significant differential gene duplication without ancestral tetraploidy in a genus of mexican fish

Summary A comparison of the protein products of 20–25 structural gene loci among the known species of the goodeid fish genusSkiffia suggests that at least 4 loci (16–20%) have undergone species-specific duplications (or, in 1 case, apparent loss) during the evolution of the genus. The species are clearly diploids, and the data therefore indicate that even a large proportion of differentially duplicated loci within a group of related fish species is not critical evidence of common tetraploid ancestry. Differential duplication of structural gene loci may be an important component of the genetic differences that separate congeneric conventional diploid species.Supported by NSF grants DEB76-20958 (BJT), DEB77-03257 (EMR) and DEB77-17315 (RRM).     

An age factor affecting variance of a behavioural character in F1 hybrids between inbred lines of the house mouse

Zusammenfassung Eines der Nestbauverhaltenselemente bei Mäusen (Beknappern von Papierstreifen) wurde bei 2 Inzuchtstämmen und deren F₁- und F₂ Hybriden verglichen. F₁-Tiere zeigten im Vergleich zu den Eltern eine grössere Variationsbreite des Verhaltenselementes. Ein grosser und besonders signifikanter Teil dieser Variabilität war einer altersabhängigen Verschiebung zuzuschreiben. Diese kommt wahrscheinlich nicht infolge eines Lernprozesses zustande, sondern durch Änderungen der genetisch-regulierenden Mechanismen (wie. z.B. Dominanz und Epistasie).

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Research supported by a grant from the Netherlands Organization for the Advancement of Pure Research (Z.W.O.). The authors are grateful to MissG. J. Blokzijl for help in making the German summary.     

nDsbD: a redox interaction hub in the Escherichia coli periplasm

DsbD is a redox-active protein of the inner Escherichia coli membrane possessing an N-terminal (nDsbD) and a C-terminal (cDsbD) periplasmic domain. nDsbD interacts with four different redox proteins involved in the periplasmic disulfide isomerization and in the cytochrome c maturation systems. We review here the studies that led to the structural characterization of all soluble DsbD domains involved and, most importantly, of trapped disulfide intermediate complexes of nDsbD with three of its four redox partners. These results revealed the structural features enabling nDsbD, a ‘redox hub’ with an immunoglobulin-like fold, to interact efficiently with its different thioredoxin-like partners. Received 3 February 2006; received after revision 1 March 2006; accepted 5 April 2006     

Artifacts from agar-protein interaction simulating a bacterial growth in the haemocultures

Summary Some morphological, histochemical and biochemical properties of the particles taking origin from the polysaccharide-proteins interaction in the presence of platelets and lymphocytes are described.     

Paratopic interaction,a mechanism in the generation of structure bound enzymatic activity

Summary A general mechanism is recognized that can cause specific enzymatic activity at interphases. It consists of 2 proteins bound in close juxtaposition at a micelle or membrane surface. One, the enzymesensu strictu, bears the active site, the other, the paraenzyme, is essential for generation or specific modification of the enzymatic activity.     

Artifacts from agar-protein interaction simulating a bacterial growth in the haemocultures.

Some morphological, histochemical and biochemical properties of the particles taking origin from the polysaccharide-proteins interaction in the presence of platelets and lymphocytes are described.