Über die Wirkung von Elastase auf die Blutgerinnung

Summary Purified elastase prepared by adsorption on synthetic zeolite in proper concentrations causes the coagulation of blood. Elastase was found to have no direct coagulative action on purified fibrinogen. Its coagulating action is due to the fact that it reacts with prothrombin to form thrombin. The reaction between prothrombin and elastase is independent of the presence of either platelets, thromboplastin or Ca-ions.     

Über die Kristallstruktur des Azulens

Résumé La structure du réseau spatial de l'azulène cristallisé a été déterminée à l'aide des rayons X. Les valeurs des constantes du réseau sont en général les mêmes que celles trouvées parMisch etvan der Wyk. Au contraire, la statistique des interférences observées montre des différences importantes et conduit au groupe spatial P 2₁/a, à la place de P 2₁ et P 2₁/m indiqué par les auteurs cités.

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Erstmals hergestellt vonPl. A. Plattner undA. St. Pfau, Helv. chim. acta20, 224 (1937).     

Über die Konstitution des Tribrom-koprostanons

Summary In the literature has been described that the further bromination of 4,4-dibromo-koprostanon results in the formation of a 2,4,4-tribromo-koprostanon. In this paper it is shown that the tribromo-compound obtained from koprostanon is a2,4,6-tribromo-cholestenon.     

Über die Konstitution des Lactaroviolins

Summary Results of partial hydrogenation support the assumption that lactaroviolin belongs to the azulen group.     

Über die Konstitution des Visamminols

Summary The structure of Visamminol (I), a compound isolated fromAmmi visnaga bySmith, Pucci, andBywater, has been elucidated by degradation and by a comparison of the UV.-spectra of I and its derivatives with those of other chromones.     

Über die Atmungsenzyme des Seeigeleies

Riassunto Le attività citocroma ossidasica, succino-deidrogenasica, DPNH e TPNH cit. c riduttasica sono state studiate in omogenati e frazioni mitocondriali e microsomiali di uova vergini e fecondate diParacentrotus lividus. I mitocondri contengono tutta l'attività citocromossidasica e succinodeidrogenasica, mentre i microsomi solo una metà della attività DPNH cit. c riduttasica totale. Spettri differenziali hanno rivelato la presenza, nei microsomi, di un citocromo avente una banda a 428–430 mµ.     

Über die Konstitution des Sempervirins

Résumé En conclusion de quelques nouvelles réactions et de la mesure de son spectre d'absorption, la formule I est proposée pour la Sempervirine C₁₉H₁₆N₂, l'alcaloïde jaune deGelsemium sempervirens.     

Über die polarographische Bestimmung des Cl'-Ions

Ohne Zusammenfassung     

Über die 1-Peptidasen des Tuberkelbazillus

Ohne Zusammenfassung     

Über die mechanische Klanganalyse des Ohrs

Summary The author shows mathematically and experimentally, that a mechanical frequency-analysis in the cochlea is possiblewithout resonance and that the yielding and damping of the basilar membrane are determinative.     

Über die antithyreotoxische Wirkung der Pantothensäure

Summary Administration of calcium pantothenate to white rats in daily doses of 50–100 mg improved the signs of experimental thyreotoxicosis and decreased the metabolic rate.     

Über die Wirkung blutzuckersenkender Sulfonylharnstoffe auf das isolierte Rattenzwerchfell

Summary The action of blood sugar depressing sulfonylureas on glucose and oxygen uptake, as well as on glycogen content and formation of C¹⁴O₂ from uniformly labelled C¹⁴-glucose was investigated in rat hemidiaphragms incubated in phosphate buffer. The following results were obtained: (1) Tolbutamide and Carbutamide increased the glucose uptake. (2) Tolbutamide decreased the glycogen-content. (3) Oxygen uptake as well as formation of C¹⁴O₂ were increased by Tolbutamide. (4) The action of Tolbutamide and insuline was equal with respect to glucose uptake but different as regarding the glycogen content, oxygen uptake and CO₂-formation.It is concluded that sulfonylureas increase glucose oxidation in the rat hemidiaphragm probably without increasing insulin sensitivity. To our knowledge this mechanism of action has hitherto not been described.     

Über die Wirkung der chronischen Colchicin-vergiftung auf experimentelle Mykosen

Summary Rats injected intraperitoneally with colchicin, 35–50 per 100 g daily or every second day, were infected experimentally on 10th day with Nocardia asteroides, Nocardia Leishmani or Torula histolytica. Controls received no colchicin. Animals given colchicin showed diffusion of infection with numerous mycotic granulomes, similar to the results obtained with cortison.     

Über die bakteriostatische Wirkung von Anthocyanen und verwandten Stoffen

Summary Some anthocyanins and flavonols have been found to have no bacteriostatic effect on pathogenic micro-organisms.     

Über die Einwirkung des Schilddrüsenhormons auf die Ossifikation

Summary Larvae ofSalamandra salamandra quadrivirgata Dürigen and tadpoles ofXenopus laevis Daud, treated with a percutaneous application of thyroxin, show a more intensive calcification of their skeletal system after a precocious metamorphosis. The calcified area of bones is increased; additional centres of calcification can be distinguished in quite a number of other skeletal elements. By thyroxin-soaked agar implants in the hindlimbs ofAmbystoma mexicanum, deposition of calcium salts is furthered in the bones of the leg treated, as well as in the adjacent pelvic girdle, thus demonstrating that the thyroid hormone exerts a direct effect upon calcification. It is supposed that during normal metamorphosis the thyroid gland plays an equal part in the process of calcification in the skeletal system.