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1.
铈对培养肝细胞的影响   总被引:13,自引:0,他引:13  
应用流式细胞术研究了稀土离子对大白鼠原代肝细胞和肝癌细胞的影响.结果表明,稀土离子可以增加原代肝细胞内DNA含量,促进细胞增殖,改变肝细胞周期时相,减少正常肝细胞凋亡,诱导肝癌细胞凋亡;钙调素也能促进细胞内DNA含量的增加,改变细胞周期时相  相似文献   

2.
银泰(1-对羟基苯基丁酮)是以银杏外种皮提纯物白果酚为先导化合物仿生合成的一种杀菌剂。其 中,银杏果实乙醇粗提物8畅3倍和25倍液对苹果腐烂病抑菌率达100%和50%;银杏果实外种皮提纯物白果酚 200倍和400倍液对苹果腐烂病病菌抑菌率均为100%。20%银泰微乳剂对苹果腐烂病、番茄灰霉病等4种病菌 EC50为17畅26~48畅43mg桙L,分别优于对照药剂;田间防治小麦纹枯病等4种病害效果达85%以上;对非靶标生物 安全,且不易产生抗药性。仿生合成的银泰原药对大白鼠毒性试验,经口、经皮LD50均为4640mg桙kg,20%银 泰乳油对大白鼠毒性试验,经口LD50为3160mg桙kg,经皮LD50为2150mg桙kg;亚慢性经口毒性(90d)试验雌为 19畅1mg桙kg,雄为18畅3mg桙kg;Ames、细胞微核和染色体畸变试验均为阴性结果。  相似文献   

3.
用广州管圆线虫雌虫冰冻切片作免疫酶染色试验(IEST),检测感染广州管圆线虫大白鼠血清中抗体,结果在感染后3—9周的39份大白鼠血清中,37份呈阳性反应,阳性率为95%,GMRT280.67;32份正常大白鼠血清,全部为阴性,检测10份猪蛔虫抗原免疫大白鼠血清;3份曼氏这宫绦虫裂头拗抗原免疫大白鼠血清;7份日本血吸虫感染大白鼠血清,均呈阴性反应。  相似文献   

4.
国外科技     
芝麻也成癌症克星 日本东京大学石川隆俊教授发现,芝麻中所含的芝麻明具有防癌功能。石川隆俊把芝麻明混入饲料中,喂养大白鼠17周。开始的头一两周内,对大白鼠注射两次致癌物质亚硝胺。结果,食用了芝麻明的大白鼠发生癌变的比例不及未食用芝麻明的二分之一。 洗衣不用洗衣粉 美国一家公司在耗资数亿美元后开发出一种装置,使洗衣机在洗衣时不用洗衣粉。这种装置能很方便地装入洗衣机内,并能将水转换成一种电控液体,使它的去污能力与合成洗衣粉相同。由于减少了漂洗过程,这种装置可  相似文献   

5.
1.中枢经系统无论处于药物兴奋或药物抑制状态均能使大白鼠肝脏中色氨酸吡咯酶活力增加,而使其诱导酶活力下降。此种酶活力的增加可能是通过腎上腺皮质激素的分泌增加而引起的。 2.声源性癫癇大白鼠在癫癎样发作时肝脏中色氨酸吡咯酶活力没有表现出明显的变化。 3.实验发现,黄鼠肝脏中也有色氨酸吡咯酶存在,其活力远较大白鼠为低,色氨酸吡咯酶在黄鼠肝脏中也能通过底物诱导生成,黄鼠处于冬眠时期此酶活力有显著的增高。 4.对于上述结果的机制进行了初步讨論。  相似文献   

6.
目的 观察大剂量静脉输注丙种球蛋白预防川崎病(KD)动脉损害的疗效。方法对KD患者86例,A组应用单次大剂量静脉输注丙种球蛋白,B组应用分次输注丙种球蛋白,C组单用阿斯匹林进行比较。结果A组病例12~24h退热达100%,临床症状改善明显优于B、C组P〈0.01。结论单次大剂量静脉滴注丙种球蛋白佐以阿斯匹林是目前理想的方法,应在急性期尽早使用。  相似文献   

7.
选取清洁级30只Wistar大白鼠随机分成三组,以小肠推进长度的百分比为指标。通过观察Wistar大白鼠在运动前、运动中30min和运动后30min小肠的推进程度变化,确定运动对Wistar大白鼠小肠推进活动的影响。实验结果表明:运动中30min的Wistar大白鼠的小肠推进程度比对照组降低;运动后30min组的Wistar大白鼠的小肠推进程度明显高于另外两组。从而得出运动有助于小肠推进活动功能,小肠动力功能能提高的结论。  相似文献   

8.
为探求血小板相关抗体的产生规律,评价血小板相关抗体筛查的临床意义,对解放军总医院43例反复输注血小板成分的患者采用ELISA方法进行HLA相关抗体筛查。8例结果为阳性,阳性率为18.6%。8例阳性患者的血小板输注次数均在20次以上,说明血小板相关抗体产生几率随着输注次数的增加而增高,选择适当时机进行血小板相关抗体筛查,根据抗体产生情况决定配型与否,既降低医疗成本,又能提高临床输注疗效。  相似文献   

9.
选取清洁级30只Wistar大白鼠随机分成三组,以小肠推进长度的百分比为指标.通过观察Wistar大白鼠在运动前、运动中30min和运动后30min小肠的推进程度变化,确定运动对Wistar大白鼠小肠推进活动的影响.实验结果表明:运动中30min的Wistar大白鼠的小肠推进程度比对照组降低;运动后30min组的Wistar大白鼠的小肠推进程度明显高于另外两组.从而得出运动有助于小肠推进活动功能,小肠动力功能能提高的结论.  相似文献   

10.
观察囊型肝包虫囊周肝细胞的病理形态学变化(肝细胞萎缩、坏死、凋亡),初步探讨囊型肝包虫病肝细胞“消失”机制。对30例肝包虫囊肿周围肝组织及10例正常肝组织通过光镜观察肝细胞的病理形态学变化,透射电镜观察6例肝包虫囊肿周围肝细胞超微结构改变,运用TUNEL法测定肝细胞凋亡并采用免疫组化技术检测30例肝包虫囊肿周围肝组织及10例正常肝组织中Bcl-2及Bax蛋白的表达。结果显示TUNEL法测定囊周肝细胞凋亡发生极少(0.12%)与正常肝(0.16%)比较无显著差异,囊周肝组织Bcl-2及Bax蛋臼呈低表达,分别为6.6%和13.3%,病理学观察囊周肝细胞明显萎缩,肝细胞坏死。因此,肝细胞萎缩、坏死、凋亡共同参与囊型肝包虫囊周肝细胞“消失”,肝细胞萎缩、坏死可能是引起肝细胞“消失”的主要机制,肝细胞凋亡可能不是引起肝细胞“消失”的主要机制。  相似文献   

11.
Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.  相似文献   

12.
何延凌 《科技信息》2008,(4):258-258
Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women's language from these perspectives: pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women's language, more attention should be paid to language use in social context. What's more, the linguistic phenomena in a speaking community can be understood more thoroughly.  相似文献   

13.
理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。  相似文献   

14.
As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.  相似文献   

15.
正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-  相似文献   

16.
We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-  相似文献   

17.
正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that  相似文献   

18.
<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with  相似文献   

19.
20.
<正>"Journal of Jilin University(Science Edition)"is a comprehensive academic journal in the fields of science sponsored by Jilin University and administrated by the Ministry of Education of the Peoples Republic of China.The journal started publication in 1955.The original name at starting publication was"Journal of Natural Science of Northeast People University",which was changed into"Acta Scientiarum Naturalium Universitatis Jilinensis"in 1958 owing to the name change of the university.The present journal name has  相似文献   

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