Fluoruration du DDT

Summary The fluorination of DDT has led to the isolation of dichloro-diphenyl-difluoro-chloroethane. The introduction of the two fluorine atoms decreases considerably the paralysing effect, but does not seem to affect the toxicity of this insecticide.     

Effect of methylendioxyphenyl synergists on metabolism of carbaryl byAspergillus terreus

Zusammenfassung Die Methylendioxyphenyl-Synergisten Sesamex und Sesamol hemmen die Umwandlung des Insektizids Carbaryl (1-Naphthyl-N-Methylcarbamat) zu N-Hydroxymethylcarbamat und 1-Naphthylcarbamat beiAspergillus terreus. Die Wirkung der beiden Synergisten ist jedoch von begrenzter Dauer, da sie durch den Pilz metabolisiert werden.

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Authorized for publication on 10 July 1974 as paper number 4732 in the journal series of the Pennsylvania Agricultural Experiment Station.     

Polarographic determination of DDT

Zusammenfassung Es wird eine schnelle, hochempfindliche polarographische Bestimmung von DDT beschrieben und das durch Nitrieren von DDT erhältliche Tetranitroderivat zur Polarographie verwendet.     

Photodegradable formulations of DDT

Summary The incorporation of diphenylamine and diethylaniline in commercial DDT-WDP formulations sprayed onPhaseolus aureus andTabernaemontana coronaria revealed that both these chemicals enhanced the initial rate of loss of DDT. Both these sensitizers exhibited no immediate adverse effect on the storage stability, pH, sieve requirement and colour of the formulations and introduced no phytotoxicity. Diphenylamine addition, however, had some adverse effects on the suspensibility.Contribution No. 103.     

Dermal toxicity of DDT

Zusammenfassung Auf die Haut von Meerschweinchen appliziertes DDT bewirkt eine Verminderung im Amino-säuregehalt des Hautgewebes. Histopathologisch wurden Veränderungen im Bereich des Gewebes und der Zellen festgestellt.

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1,1,1-Trichloro-2, 2-bis(P-chlorophenyl ethane) (P-PDDT). P-P, isomer of 99.8% purity was generously supplied to us by J. R. Geigy & Co., Baslc, and their help is gratefully acknowledged by the authors.     

Photodegradable formulatins of DDT.

The incorporation of diphenylamine and diethylaniline in commercial DDT-WDP formulations sprayed on Phaseolus aureus and Tabernaemontana coronaria revealed that both these chemicals enhanced the initial rate of loss of DDT. Both these sensitizers exhibited no immediate adverse effect on the storage stability, pH, sieve requirement and colour of the formulations and introduced no phytotoxicity. Diphenylamine addition, however, had some adverse effects on the suspensibility.     

Fate of internal doses of DDT

Résumé Des doses de C¹⁴DDT de l'ordre de 2.5 injectées dans le thorax de mouches domestiques—témoins restèrent localisées. Des auto-radiographes du thorax montrent que la courbe de concentration de l'insecticide décroît vers la périphérie. On peut donc présumer que chez l'insecte la circulation joue un rôle mineur dans le transport du DDT vers son site d'action.     

Detection of DDT in quail eggs: quantitative analysis]

Significant residues of DDT have been found in the albumin and vitellus of Quail eggs, after external treatment of the shell with an aqueous suspension of commercial DDT. The rate of pesticide crossing varies according to the shell porosity and thickness. Residues of DDT have also been found in the control eggs and in the Quail industrial food.     

A new physical theory of the mode of action of DDT

Résumé Les relations quantitatives ont été établies entre la fréquence des impulsions et les dessins d'activité électrique de la nervure crurale deSchistocerca gregaria Forsk., d'une part et la température et le dosage de DDT d'autre part. Ces données-ci ont rendu possible une nouvelle hypothèse de l'action du DDT.     

Influence of three synergists on the action of some insecticides against parental and resistant strains of the Egyptian cotton leafworm

Summary Piperonyl butoxide, MGK 264 and DEF acted as synergists when used together with endrin and methomyl against the Egyptian cotton leafwormSpodoptera littoralis. The synergistic effect was higher with resistant strains than with the parental strain. The three substances tested as synergists actually antagonized the action of phospholan and cypermethrin on the parental strain, though they had some activity as synergists with these insecticides on resistant strains. The synergistic effect of DEF was higher than that of piperonyl butoxide or MGK 264, particularly on resistant strains.     

Occurrence of DDT and BHC residues in human milk in India

Summary Samples of human milk from Punjab, India have shown the presence of DDT and BHC residues in amounts greater than those reported from most of the other countries.This research has been financed in part by a grant made by the United States Department of Agriculture, Agricultural Research Service authorized by Public Law 480.     

Occurrence of DDT and BHC residues in human milk in India

The presence of pesticide residue of DDT and of BHC were determined in 1979 in samples of milk from 75 lactating mothers from Punjab, within a week after delivery. DDT and BHC residues were found present in all 75 samples collected. Recovery of isomers of BHC and metabolites/isomers of p.p'-DDT from the spiked samples was above 80%. The mean level of DDT residue was 0.51 ppm, which is more than the level reported from the U.S., Canada, Europe and Australia, but less than the level found in Guatemala. BHC residues also were higher than those found in other countries, with the exception of Japan. DDT level of 0.5 ppm in milk represents an infant intake of 0.09 mg/kg/day, which is 18 times the acceptable daily intake (0.005 mg/kg/day) recommended by the WHO. Acceptable daily intake of BHC has not yet been established.     

Investigations on the effects of chronically administered small amounts of DDT in mice

Zusammenfassung BALB-c Mäusen wurde während 5 Generationen DDT (0,3–0,6 mg/kg Körpergewicht) verabreicht. Bei 61 Tieren (8,92%) traten maligne Veränderungen ein (Leukemien, Tumoren), während in der Kontrollgruppe nur 5 Tiere (1,22%) erkrankten.