基于SVM分类机的一种DNA序列判别方法

针对DNA序列类别的分属问题,提出采用支持向量机（Support Vector Machine,SVM）的方法进行分类。根据SVM分类器的要求建立特征属性空间,首先由每个DNA中4个碱基的含量得到4个特征属性,然后在此空间中扩充DNA序列长度的属性,最后根据SVM分类器对已知的DNA分类样本做训练得到分类超平面。利用此超平面检测所要分类的DNA序列,实验结果表明这种方法具有很好的分类精度。     

DNA序列二维图表示和有关分析

在DNA序列研究中,对长DNA序列进行有效表示,可以为DNA序列的分类、分析和比较等研究提供创新性的方法. Nandy,Leong和Mogenthaler,Randic等已经给出了DNA序列的二维或三维图表示. 这些图表示给出了DNA序列的可视化特征. 文中给出了一个改进的DNA序列的图表示:在2维指数坐标系内用4个特定的向量分别表示DNA序列中的4个碱基,从而使DNA序列可以用有向路表示. 给出了一个例子说明该方法的有效性,可以证明该种改进的DNA序列图表示方法具有较低的退化度甚至没有退化.     

DNA序列特征提取方法研究

针对DNA序列分类问题提出了两种特征提取方法,利用可分支持向量分类机间隔大、推广能力强的原理建立了DNA序列特征提取方法优劣的评价标准,利用该标准把本文的两种特征提取方法进行了比较,且跟以往的DNA序列特征提取方法进行了比较.实验表明,提出的两种特征方法得到的DNA序列特征完全能够代表DNA序列,对已知分类样本的预测率为100%,且此特征提取方法有很强的推广能力.     

基于4D表示的DNA序列分析方法

基于DNA序列4种核苷酸的物理化学性质,考虑相邻两个碱基组合形式,提出一种新的DNA序列4D表示.基于这种表示,可以把DNA序列简化成4D空间的一系列点,根据点坐标抽取序列数值特征,再根据数值特征给出方法对DNA序列进行相似性分析.以10个不同物种的a-球蛋白基因的第一个外显子碱基序列的为例子,说明基于4D表示的DNA序列分析方法是有效的.     

概率密度函数的特征相关法DNA序列分析(英文)

提出了一种客观的特征提取和相关的方法用于DNA序列的结构分析.这种方法是从DNA序列码的碱基和片段码中提取统计特征和相关特征.然后计算样本序列和已知类之间的平均相关系数.如果最大的相关系数大于对应类的平均相关系数,则该样本被分类到对应的类中去.利用一组DNA序列样本做了试验,结果表明,这种方法适合于任何DNA序列的结构分析而不需要先念的生物信息,对发掘人类基因隐藏信息的研究大有用处。     

DNA序列非退化的二维图形表示及其应用

提出了一种新的DNA序列的2-D图形表示方法,并证明了它的非退化性,随后结合图形表示给出DNA序列的12个正规化的ALE指标.在此基础上,结合双核苷酸计数和符号序列LZ复杂度,将DNA序列转化为一个29维的数值向量.对23个物种的β球蛋白基因和18个物种的线粒体NADH脱氢酶序列进行的系统发生分析,证明了所提方法的有效性.     

递归迭代函数系统对DNA序列可视化表示的模拟

DNA序列的可视化表示——混沌游戏表示(CGR)呈现出了分形特征.根据分形的产生机理,文章用递归迭代函数系统(RIFS)模型模拟了DNA序列的混沌游戏表示,并通过比较递归迭代函数系统的吸引子的不变测度与混沌游戏表示的测度之间的差异,得出该方法对DNA序列的混沌游戏表示的逼近效果良好这一结论.基于该方法,人们可以对DNA序列的混沌游戏表示作进一步的分析.     

等输入模型下DNA序列点突变的熵性质

目的:研究在等输入模型下DNA序列熵随世代变化的规律及其性质.方法:基于Shannon信息熵理论,在等输入模型下建立有限长DNA序列点突变微分方程组模型,利用Lagrange乘数法进行理论证明,并用Mathematica软件模拟等输入模型下DNA序列熵的变化过程.结果:DNA序列在等输入模型下发生突变,其熵随世代增加随机波动,且趋于最大值.结论:DNA序列点突变具有"保熵性",并验证了生物是朝着多样性增大方向进化的理论.     

运用功率谱分析预测基因组序列编码区

基因组序列中蛋白编码区的正确预测是后基因组时代的一个重要工作.采用分解子序列的方法将DNA序列映射为数值序列,然后对其进行功率谱分析,DNA序列的功率谱曲线的峰值位置刚好和编码区序列相对应,从而实现了对基因组序列编码区的预测.理论分析和大量计算机实验证实了方法的有效性,预测的探测率和正确率分别达到97%和88%,预测效果良好.该方法不需要基因组序列的任何先验知识,应用面广.     

基于聚合酶链置换反应的2D-LASM混沌文本加密算法

针对现有的基于DNA序列进行信息加密算法中没有涉及到DNA计算中化学反应这一问题,提出了基于聚合酶链置换反应的2D-LASM混沌映射文本加密算法.该算法将混沌映射产生的伪随机序列和明文信息进行异或操作,然后转换成DNA序列;随后再将DNA序列进行聚合酶链置换反应得到新的DNA序列.对新的DNA序列进行解码,得到密文.最...     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

An Analysis of Catherine＇s Character——Wuthering Heights

Wuthering Heights, Emily Bronte＇s only novel, was published in December of 1847 under the pseudonym Ellis Bell. The book did not gain immediate success, but it is now thought one of the finest novels in the English language. Catherine is the key character of this masterpiece, because everybody and everything center on her though she had a short life. We can understand this masterpiece better if we know Catherine well.     

Lower Paleozoic oil relationships within Williston Basin, Canada

The Williston Basin is a significant petroleum province, containing oil production zones that include the Middle Cambrian to Lower Ordovician, Upper Ordovician, Middle Devonian, Upper Devonian and Mississippian and within the Jurassic and Cretaceous. The oils of the Williston Basin exhibit a wide range of geochemical characteristics defined as "oil families", although the geochemical signature of the Cambrian Deadwood Formation and Lower Ordovician Winnipeg reservoired oils does not match any "oil family". Despite their close stratigraphic proximity, it is evident that the oils of the Lower Palaeozoic within the Williston Basin are distinct. This suggests the presence of a new "oil family" within the Williston Basin. Diagnostic geochemical signatures occur in the gasoline range chromatograms, within saturate fraction gas chromatograms and biomarker fingerprints. However, some of the established criteria and cross-plots that are currently used to segregate oils into distinct genetic families within the basin do not always meet with success, particularly when applied to the Lower Palaeozoic oils of the Deadwood and Winnipeg Formation.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

Design and analysis of generic LBS application developing platform

Location based services is promising due to its novel working style and contents.A software platform is proposed to provide application programs of typical location based services and support new applications developing efficiently. The analysis shows that this scheme is easy implemented, low cost and adapt to all kinds of mobile nework system.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Density Functional Theory for the Response of Periodic Systems to Electric Fields Based on the Vector Potential Approach

正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that