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DDT in California sea lions   总被引:1,自引:0,他引:1  
B J Le Boeuf  M L Bonnell 《Nature》1971,234(5324):108-110
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《Nature》1971,229(5286):514-515
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Petit C 《Nature》2005,438(7067):410-412
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Grüning NM  Ralser M 《Nature》2011,480(7376):190-191
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Nitrate pollution of groundwater is paid more and more attention for its hazardous to environments and human health. A strain of DN11 was isolated from soil and used in the laboratory columns filled with various media for nitrate removal. The experimental results showed that DN11could reduce nitrate at different rates in different media under the aerobic condition. The mechanism for nitrate removal with DN11 is explained meanwhile.  相似文献   

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Molecular genetic evidence for heterogeneity in manic depression   总被引:7,自引:0,他引:7  
Manic depression is a severe cyclic mental illness that can be unipolar or bipolar and has a lifetime risk of approximately 7 per 1,000 in most populations. Families with multiple cases of manic depression have been described that are compatible with both autosomal dominant and X-linked modes of genetic transmission. Psychoactive antidepressant and stimulant drugs that help to ameliorate depression and mania are thought to act by affecting catecholamine neurotransmitter systems such as adrenaline, noradrenaline and dopamine, amongst others. Mutations affecting the tyrosine hydroxylase (TH) gene, which encodes the rate-limiting enzyme for the synthesis of these three neurotransmitters, might therefore be responsible for causing the manic depressive phenotype. We have studied three Icelandic kindreds amongst whom it appears that a single autosomal dominant disease allele is segregating. In these families there were 44 cases amongst 73 individuals at risk. Genetic linkage studies were carried out using clones encoding tyrosine hydroxylase the variable portion of the Harvey-ras-1 (HRAS1) locus and the variable region of the insulin gene (INS). All three markers are closely linked on chromosome 11 and were used to observe the segregation of restriction fragment length polymorphisms (RFLPs) in the three affected kindreds. We found no evidence for linkage to these markers in any of the three families. In contrast, Gerhard et al. found linkage between manic depression and HRAS1 in a single large Amish kindred. We conclude that there is genetic heterogeneity of linkage in manic depression. Therefore mutations at different loci are responsible for the manic depressive phenotype in the Amish and in Iceland.  相似文献   

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Direct evidence for atomic defects in graphene layers   总被引:1,自引:0,他引:1  
Hashimoto A  Suenaga K  Gloter A  Urita K  Iijima S 《Nature》2004,430(7002):870-873
Atomic-scale defects in graphene layers alter the physical and chemical properties of carbon nanostructures. Theoretical predictions have recently shown that energetic particles such as electrons and ions can induce polymorphic atomic defects in graphene layers as a result of knock-on atom displacements. However, the number of experimental reports on these defects is limited. The graphite network in single-walled carbon nanotubes has been visualized by transmission electron microscopy (TEM) and their chiral indices have been determined. But the methods used require a long image acquisition time and intensive numerical treatments after observations to find an 'average' image, which prevents the accurate detection and investigation of defect structures. Here we report observations in situ of defect formation in single graphene layers by high-resolution TEM. The observed structures are expected to be of use when engineering the properties of carbon nanostructures for specific device applications.  相似文献   

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Real-time forecasts of tomorrow's earthquakes in California   总被引:4,自引:0,他引:4  
Despite a lack of reliable deterministic earthquake precursors, seismologists have significant predictive information about earthquake activity from an increasingly accurate understanding of the clustering properties of earthquakes. In the past 15 years, time-dependent earthquake probabilities based on a generic short-term clustering model have been made publicly available in near-real time during major earthquake sequences. These forecasts describe the probability and number of events that are, on average, likely to occur following a mainshock of a given magnitude, but are not tailored to the particular sequence at hand and contain no information about the likely locations of the aftershocks. Our model builds upon the basic principles of this generic forecast model in two ways: it recasts the forecast in terms of the probability of strong ground shaking, and it combines an existing time-independent earthquake occurrence model based on fault data and historical earthquakes with increasingly complex models describing the local time-dependent earthquake clustering. The result is a time-dependent map showing the probability of strong shaking anywhere in California within the next 24 hours. The seismic hazard modelling approach we describe provides a better understanding of time-dependent earthquake hazard, and increases its usefulness for the public, emergency planners and the media.  相似文献   

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为解决Dempster-Shafer证据理论在对高度冲突的证据进行融合时可能导致与直观相悖的结果的问题,该文提出了一种有效处理冲突证据的融合方法。该方法综合了Dempster-Shafer证据理论所具有的收敛性好及加性融合方法所具有的可靠性高的优点,首先通过对证据进行冲突检验,然后对冲突证据进行加性合成,消除证据之间的冲突。仿真试验结果表明该算法能更好地排除干扰,得出符合实际的组合结果,与典型算法相比,该方法在收敛性和可靠性方面体现了优越性。  相似文献   

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