In vivo and in vitro incorporation of 3H-thymidine in the uterus of the rabbit during pseudopregnancy

During pseudopregnancy in the Rabbit the DNA synthesis in the uterine epithelium is very reduced. These results conjoined with the decrease of the mitotic index and previous ultrastructural observations allow to think that multinucleated cells proceed mainly by cell fusion.     

Differences in in vitro incorporation of tritiated deoxycytidine and tritiated thymidine into human lymphocytes

Summary Human lymphocytes stimulated in vitro by PHA or PWM incorporate³H-CdR into DNA, but less well than³H-TdR. More³H-CdR is incorporated in populations enriched for T cells. No³H-CdR is used by cells stimulated by lipopolysaccharides under circumstances in which³H-TdR is incorporated. We conclude that human T cells and B cells differ in their ability to use³H-CdR.     

Differences in in vitro incorporation of tritiated deoxycytidine and tritiated thymidine into human lymphocytes.

Human lymphocytes stimulated in vitro by PHA or PWM incorporate 3H-CdR into DNA, but less well than 3H-TdR. More 3H-CdR is incorporated in populations enriched for T cells. No 3H-CdR is used by cells stimulated by lipopolysaccharides under circumstances in which 3H-TdR is incorporated. We conclude that human T cells and B cells differ in their ability to use 3H-CdR.     

The influence of reserpine on incorporation of3H-thymidine into mouse liver DNA

Zusammenfassung Der Einbau von³H-Thymidin in die DNA der Leber von weiblichen weissen Mäusen wurde 60 h nach der Verabreichung von 2 mg/kg Reserpin und ausserdem 60 h nach Futterentzug an nicht reserpinisierten Tieren gemessen. Reserpin führt unabhängig von der unter dieser Substanz auftretenden Hypothermie und Anorexie zu einer Hemmung des³H-Thymidin-Einbaus in die DNS der Leber um etwa 60%.     

A differential effect of L-serine on the incorporation of3H-deoxycytidine and3H-thymidine into DNA of rat thymocytes

Summary The addition of L-serine to short-term cultures of rat thymocytes stimulated the incorporation of³H-deoxycytidine into DNA, but simultaneously depressed the incorporation of³H-thymidine into DNA.This investigation was supported by NIH grants No. CA-10291 and T12CA8021 from the National Cancer Institute.     

A differential effect of L-serine on the incorporation of 3H-deoxycytidine and 3H-thymidine into DNA of rat thymocytes.

The addition of L-serine to short-term cultures of rat thymocytes stimulated the incorporation of 3H-deoxycytidine into DNA, but simultaneously depressed the incorporation of 3H-thymidine into DNA.     

Effect of aflatoxin B1 on the in vitro incorporation of14C-acetate into human skin lipids

Zusammenfassung Aflatoxin B₁ hindert den in vitro Einbau des¹⁴C-Azetats in die Gesamtlipide, die freien Sterine, die Phospholipide und die Neutralfette der menschlichen Haut. Die Atmungsgeschwindigkeit der toxinbehandelten Gewebe wurde nicht beeinflusst.     

3H-thymidine incorporation (DNA synthesis) and radiotoxicity in the ovary of the Japanese quail before and during follicle formation

No evidence was found for ribosomal DNA amplification in the oocytes of the Japanese quail, before or during folliculogenesis. DNA synthesis in the somatic cells, involved in follicle formation, starts at the medullar side of the basement membrane. The localized sterilization of the quail ovary after administration of 3H-thymidine (3H-TdR) seems to be due to radiation-induced lesions in the follicle forming somatic cells, rather than to direct radiation damage of the oocyte.     

Extranuclear3H-thymidine incorporation in subcortical cytoplasmic organelles of primary oocytes in the Japanese quail (Coturnix coturnix japonica)

Résumé Après une injection intrapéritonéale de thymidine³H à la caille japonaise pondeuse, nous avons trouvé une incorporation de ce précurseur dans des organites cytoplasmiques subcorticaux des oocytes, quelques jours avant leur ovulation.     

The effects of non-thermal radio frequency radiation on human lymphocytes in vitro

Zusammenfassung Hypotonische Streuungen, die in radiobestrahlten Kulturen menschlicher Lymphozyten Chromosomenaberrationen erkennen liessen, traten dort siebenmal häufiger auf als in unbestrahlten Kulturen; offenbar das Ergebnis einer wärmefreien Bestrahlung. Trotz des Fehlens bedeutender Unterschiede in der DNA-Synthese, der Zellvergrösserung und im mitotischen Index zwischen bestrahlten und unbestrahlten Kulturen kam es zu Aberrationen.     

alpha-Mercaptopropionyl-glycine influence on the in vitro proliferative response of human lymphocytes.

The effect of alpha-mercaptopropinyl-glycine on the in vitro proliferative response of healthy subjects' lymphocytes was studied. Low doses of the drug enhanced spontaneous lymphocyte blastigenesis but had no effect on the PHA-induced blastic response. With increasing concentrations of alpha-mercaptopropionyl-glycine inhibition of 3H-thymidine incorporation was found in unstimulated as well as in PHA stimulated lymphocytes.     

Partial masculinization of genetic female chickens (Gallus gallus) after incorporation of3H-thymidine during the period of oogenesis

Résumé L'apparition de caractères mâles localisés à la tête et à la nuque a été observée chez des poules génétiquement femelles après des applications successives de thymidine tritiée pendant la période de l'ovogenèse.