The effect of basic vital dyes on the acid phosphatase activity of the granulated juxtaglomerular cells

Zusammenfassung Die histochemisch nachweisbare saure Phosphataseaktivität der juxtaglomerulären granulierten Zellen wurde durch Vitalfärbung mit Neutralrot aufgehoben. Diese Zellen sind auch mit anderen Vitalfarbstoffen; Acridinorange, Nilblausulfat, Brillantkresylblau färbbar, ohne dass die saure Phosphataseaktivität aufzuheben ist.     

Inhibitory effect of some antrogenic hormones, administered in ovo after sex differentiation, on the development of Müllerian ducts in female bird embryos]

Some androgenic hormones injected into the vitellus of quail (8 and 10 days old) or chick eggs (10 and 12 days of incubation) inhibit the left Müllerian duct development and mainly that of the shell gland. They slow down or stop the right duct involution. After these effects, histo-pathogenic disturbances, affect them.     

Effect of progesterone on male and female sex behavior induced by steroid hormones in adult ovariectomized ewes]

Ovariectomized adult Ewes daily treated with I/M injections of testosterone propionate (10 mg/day) or oestradiol benzoate (200 microgram/day) show male-like sexual behaviour and simultaneously a permanent female receptivity. Additional daily treatment with 100 mg of progresterone results in a rapid decrease in male sexual responses both when Ewes are treated with testosterone and with oestradiol. No effect is observed on the female receptivity. Cyproterone acetate (100 mg/day) given to Ewes in addition to daily injection of testosterone propionate (10 mg/day) has effects similar to those of progesterone. These results show that progesterone has antiandrogen and antioestrogen properties and that this hormone administered at high doses is able to inhibit male activity.     

Effects of female sex hormones on polyamine-oxidizing enzyme activities and polyamine concentrations in immature rat uterus and liver

17-estradiol (E₂) and progesterone (P) treatment of immature female rats (10 g/100 g body weight) respectively resulted in 1.38-fold (p<0.02) and 1.42-fold (p<0.02) increase in the uterine polyamine oxidase activity, and 2.45-fold (p<0.001) and 1.43-fold (p<0.02) increase in the uterine diamine oxidase activity, as compared to the controls. E₂ caused a 5-fold (p<0.05) and a 1.36-fold (p<0.05) increase in putrescine and spermidine concentration respectively in rat uterus. Increases of 1.7-fold (p<0.02) and 1.6-fold (p<0.05) in putrescine and spermine concentration were determined in the P-treated uterus, as compared to the controls. The spermidine/spermine ratio, which is regarded as an index of growth rate, was higher in the E₂-treated uterus and lower in the P-treated uterus than in the control uterus. No statistically significant hormonal effects were estimated in the immature liver. The data reported suggest the possibility of an involvement of polyamine-oxidizing enzymes in the modulation of polyamine concentrations in rat uterus by the female sex hormones.     

The effect of litter rank on the secondary sex ratio

Zusammenfassung Es wird gezeigt, dass sich verschiedene Mäusestämme im sekundären Geschlechterverhältnis unterscheiden. Die Wurffolge beeinflusst zwar die relative Zahl der Geschlechter bei der Geburt, aber dieser Einfluss wechselt mit dem Stamm selber. Der Ausgleich des Unterschieds in späteren Würfen erfolgt durch Weibchenüberschuss. Sowohl erbliche wie nichterbliche Faktoren spielen eine Rolle in der Beeinflussung des Geschlechterverhältnisses.     

The action of sex hormones on endometrial secretion in spayed rats sensitized to oestradiol

Zusammenfassung Ligatur der distalen Enden der Uterushörner von adulten, kastrierten, mit Östradiol sensibilisierten Ratten hat eine Ansammlung der uterinen Flüssigkeit zur Folge. Die Wirkung von Östradiol, Testosteron und Progesteron auf die Eigenschaften dieser Flüssigkeit wurde untersucht. Während Östradiol in verschiedenen Dosen keinen signifikanten Effekt aufweist, zeigt Testosteron und besonders Progesteron eine ausgeprägte Wirkung. Sie reduzieren die Menge der Flüssigkeit, erniedrigen das pH und steigern die Viskosität. Diese Veränderungen könnten für die Hemmung der Fertilität durch diese Substanzen von Bedeutung sein.     

The effect of lithium carbonate on the granulocyte phagocytic index

Summary Preincubation in lithium carbonate of granulocytes from normal human male volunteer subjects did not alter the ability of these cells to perform properly the ingestion phase of phagocytosis in vitro.The voluntary fully informed consent of the subjects used in this research was obtained as required by AFR No. 169-8.Acknowledgements. Mr.A. J. Rahe of the Biometrics Division, USAF School of Aerospace Medicine, Brooks Air Force Base, TX. provided the statistical analysis. The LC used in this study was provided through the courtesy of Pfizer, Inc., Brooklyn, N.Y., USA.     

Effect of sex hormones on uric acid metabolism in rats.

The effects of sex hormones on purine metabolism were investigated in rats. No influence on purine synthesis was shown by the injection of estrogen and androgen. The plasma urate levels were significantly lowered from 2.43 +/- 1.04 mg/100 ml to 1.53 +/- 0.57 mg/100 ml by the injection of progesterone. Urinary excretion of uric acid plus allantoin was slightly reduced. These results suggested that progesterone may influence age and sex differences in human plasma urate levels.     

The effect of the gastrointestinal hormones on small intestinal motility and blood flow

Zusammenfassung Nachweis, dass Pentagastrin und CCK, in physiologischen Dosen bei der Katze infundiert, nur geringfügige Durchblutungseffekte im Dünndarmgebiet zeigen, während Sekretin über einen offenbar verschiedenen Mechanismus die Durchblutung erhöht.     

Volatile sex pheromone in the female German cockroach

Virgin German cockroach adult females release an attractant that can be extracted with organic solvents and trapped from air blown over sexually receptive females. Behavioral assays with an olfactometer showed that the attractant was produced exclusively by adult females and it elicited behavioral responses in adult males, confirming its function as a female sex pheromone. Using behavioral and electrophysiological assays, we localized the site of pheromone production on the tenth abdominal tergite where an adult female-specific gland is found. Females whose glands were ablated were significantly less attractive to males than sham-operated control females.     

Effects of sexual hormones on gonadotrophin secretion in prepuberal female rats

Resumen Los estrógenos ejercen sobre la rate hembra un efecto de retroalimentación negativo sobre la secreción de gonadotrofinas a los 20 días de edad y un efecto positivo a los 28 días de edad. La testosterona inhibió la secreción de gonadotrofinas en ratas de 20 días, pero no tuvo efecto a los 28 días de edad. En los animales androgenizados al nacer ambas hormonas inhiben la secreción de gonadotrofinas a los 20 y a los 28 días de edad.

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Supported by a grant from the Consejo Nacional de Investigaciones Científicas y Técnicas. Repùblica Argentina.