抗生素发酵微机控制系统中的数据处理技术

本结合制药生产中的抗生素发酵过程对微机数据处理技术进行了简要的阐述，主要包括有效性检查技术、数字滤波技术、非线性补偿技术和标度转换，并给出了简单的流程和程序。     

一类非线性动态系统的参数辨识和状态估计

为了对青霉素发酵过程采用计算机控制，提出了一种适合于一类非线性动态系统参 数辨识的方法。同时，根据在线获取的可测信息（二氧化碳释放率），利用随机状态估 计原理，实时估计了青霉素发酵过程中不可测的状态变量（菌体浓度、基质浓度、产 物浓度）。对实验室和生产现场提供的几批数据进行了计算机仿真，结果表明：文中所 提供的技术方案对青霉素生产过程实现状态监控是可行的。     

化工生产过程计算机仿真控制系统

针对大型化工生产过程控制的仿真对各类操作人员的培训问题,以自主开发设计的甲醇和碳酸二甲酯生产过程仿真控制系统为背景,阐述了化工生产过程计算机仿真控制系统的建模技术及模型求解方法,并给出了基于PID的调节器参数整定方法以及主要控制过程的PID控制仿真实例,该系统不仅适用于化工企业员工的上岗培训,而且适用于化工专业学生的生产实习.     

民用飞机设计中的仿真重用研究

本文对仿真的核心内容（姿态和动作）进行归类分析．分别建立姿态库和动作库，通过快速调用相似的姿态和动作实现对相似维修过程仿真的重用     

妥布霉素产生菌黑暗链霉菌F_(-211)发酵特性研究

从黑暗链霉菌Ｆ－２１１合成妥布霉素（Ｔｏｂｒａｍｙｃｉｎ）的发酵原理出发,研究黑暗链霉菌产生抗生素的特性,考察与生产妥布霉素紧密相关的种龄、周期、关键原料—油,和影响生物合成抗生素的各种主要因素,绘制出合理的发酵工艺控制图,优化发酵条件,使发酵单位提高了近一倍．     

基于时间倒推和流程仿真炼钢生产计划的制定

合理的生产计划制定与执行是生产顺利进行的有效保证．通过对炼钢连铸生产特点分析,提出基于时间倒推法和流程仿真相结合的用于炼钢连铸生产计划的制定方法,利用时间倒推法快速生成满足一定生产目标的生产作业计划,并作为炼钢物流仿真模型的仿真输入条件,通过模型仿真可进一步制定出考虑了生产过程的时间随机性、运输设备限制,并满足无设备冲突、连浇生产等约束条件的生产计划,提高计划在实际生产的可执行性．应用实例证明了该方法的可行性．     

基于FLNN的多粘菌素发酵过程建模

为解决由于缺乏传感器使众多状态参数难以在线测量的问题，建立了多粘菌素的发酵过程模型，对许多重要的状态参数进行了预估．通过在FLNN内部增加一个带有局部激活反馈和一个局部输出反馈的自回归滑动平均滤波器使其成为动态的FLNN网络，并把它运用于多粘菌素发酵过程的建模中，结合遗传算法实现对其发酵过程的茵体浓度、总糖浓度和相对效价进行预估，为实际生产和优化控制提供了有利条件．仿真结果表明，基于改进的FLNN建立的多粘菌素发酵过程模型预估效果良好．     

全连铸生产调度系统仿真模型的建立

对具有离散事件系统特征的全连铸车间生产调度系统，通过建立其仿真模型进行试验，实现了借助计算机仿真全连铸生产过程，编制了相应调度程序软件，给出多种优化调度方案图，可供实际生产调度参考使用。     

神经网络多变量监控系统在发酵工业中的应用

以发酵工业过程监控为研究对象，根据发酵过程工况参数实时检测困难的特殊性，提出了一种基于神经网络的监控体系框架，对用神经网络组成的静态预报模型和动态监测模型的有机结合应各自组成结构的特点进行了较详细的分析和研究。最后，以酒精发酵过程监控为仿真研究对象，做了仿真实验，仿真结果令人满意。在实践中经过不断完善，完全可以应用于实际生产。     

化工生产实习教学模式探讨

文中通过对化工生产实习现状的分析，提出了计算机仿真实习的教学模式，并对仿真系统的建立、操作及对教学的推动作用进行了探讨。     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Density Functional Theory for the Response of Periodic Systems to Electric Fields Based on the Vector Potential Approach

正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that     

On the Thermodynamic Limit for Responses to Static Electromagnetic Fields

For molecular systems,the quantum-mechanical treatment of their responses to static electromagnetic fields usually employs a scalar-potential treatment of the electric field and a vector-potential treatment of the magnetic field.Although the potential for each field separately is associated with the choice of an(unphysical)origin,the precise choice of the origin for the electrostatic field has little consequences for the results.This is different for the     

An affordable accurate evaluation of the binding conformations predicted by molecular docking studies in bio-system

Franck-Condon factors bridge the gap between theoretical modeling and experimental observations for molecular electronic spectroscopy and electron transfer.Under the displaced harmonic oscillator approximation,multidimensional Franck-Condon factors are decomposed into a product of many one-dimensional(1D)Franck-Condon(FC)factors,and each 1D-FC factor is associated with one Huang-Rhys factor that determines the leading contribution of     

Call for Papers

<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with     

Journal of Donghua University ( English Edition) Contents of Volume 31

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