桂哌齐特联合参麦注射液对充血性心力衰竭患者的临床研究

目的观察桂哌齐特联合参麦注射液治疗充血性心力衰竭患者的疗效。方法60例充血性心力衰竭住院患者随机分为常规对照组（30例）和桂哌齐特联合参麦注射液组（治疗组）（30例）,观察用药前、后两组患者的心率、血压,检查肝肾功能、尿常规、血清电解质等,超声心动图测量左心室舒张末期内径（LVDd）和左心室射血分数（LVEF）,按NYHA心功能分级标准评定心功能。结果治疗组有效率高于对照组,差异有显著性;两组治疗后治疗组LVEF和收缩压低于对照组,差异有显著性。结论桂哌齐特联合参麦注射液能提高充血性心力衰竭的治疗效果,患者耐受性较好,不良反应轻,有较好的临床实用价值。     

卡维地洛治疗慢性充血性心力衰竭42例

目的 :观察卡维地洛治疗慢性充血性心力衰竭的临床疗效。方法 :随机将 42例病人分为两组 ,A组常规抗心力衰竭药物治疗。B组在常规抗心力衰竭药物治疗基础上加用卡维地洛 (5mg,2次/日→ 2 5mg,2次/日 ) ,疗程 6个月 ,观察治疗前后心率及左室射血分数。结果 :治疗均降低心率及增加左室射血分数。但两组比较 ,B组较A组疗效显著 (P <0 .0 5)。结论 :β受体阻滞剂卡维地洛可有效降低心衰竭患者心率及增加左室射血分数 ,改善心衰患者症状     

双曲美他嗪治疗60例心肌梗死后心力衰竭临床观察

目的观察曲美他嗪治疗心肌梗死后心力衰竭的临床疗效。方法60例心肌梗死后心力衰竭患者随机分为观察组与治疗组。观察组行常规药物治疗,治疗组在常规治疗的基础上加用曲美他嗪20mg／次,3次／d,30d为1疗程。观察治疗前后心功能改变与心脏超声多普勒心功能指标变化。结果治疗后治疗组心功能改善总有效率为93．3％,观察组心功能改善总有效率为80．0％,两组差异有统计学意义（P〈0．05）。左心室射血分数（LVEF）及左心室短轴缩短率（FS）,治疗后治疗组较观察组明显增加,自身对照两组治疗后左心室收缩末期内径（LVSD）、左心室舒张末期内径（LVDD）明显降低,但治疗后两组间对比,差异无统计学意义（P〉0．05）。结论曲美他嗪治疗心肌梗死后心力衰竭可获得较好的临床疗效。     

心衰方治疗充血性心力衰竭患者的临床观察

目的观察心衰方对充血性心力衰竭（CHF）患者的临床疗效。方法属NYHA心功能分级为2～3级的门诊及住院患者160例随机分为两组。两组患者均给以病因及对症治疗,对照组按心力衰竭常规处理;治疗组在常规处理的基础上使用心衰方每日一剂分三次服用。观察治疗前后临床症状、体征积分变化;超声心动图指标及运动耐量、生活质量的变化。观察周期共1年。结果（1）两组患者治疗后症状、体征积分均较治疗前降低,治疗组较对照组积分更低（P〈0．05）。（2）治疗组左心室收缩末期容积较治疗前降低,每搏量、有效心输出量、心脏指数、左心室射血分数明显增加与对照组比较差异有统计学意义（P〈0．05）,提示心脏的收缩功能改善,心排血量增加。与对照组疗效比较差异有统计学意义（P〈0．05）。（3）治疗组综合疗效总有效率为94．7％,对照组综合疗效总有效率为75％。组间比较差异有统计学意义（P〈0．05）。（4）治疗组的运动耐量、生活质量与对照组比较有较显著提高（P〈0．05）。结论心衰方对充血性心力衰竭具有良好防治作用。     

卡维地洛与胺碘酮联合治疗心律失常疗效观察

观察卡维地洛与胺碘酮联合治疗心律失常的临床疗效。选取甘肃省庄浪县人民医院收治的112例心律失常患者为研究对象,将其随机分为对照组和研究组,各56例。所有患者均给予溶栓、抗凝、抗血小板基础治疗,对照组在此基础上给予胺碘酮治疗,研究组在对照组基础上联合卡维地洛治疗。比较两组治疗前后心率、收缩压、左心室射血分数、超敏C反应蛋白水平及临床疗效。两组治疗前心率、收缩压、左心室射血分数、超敏C反应蛋白水平比较差异无统计学意义(P0.05),两组治疗后以上指标水平均改善,且研究组改善效果优于对照组(P0.05);研究组临床有效率94.64%,高于对照组的75.00%(P0.05)。卡维地洛与胺碘酮联合治疗心律失常可改善患者相关指标水平,提高临床有效率,为临床研究提供参考依据。     

基于全卷积网络的左心室射血分数自动检测

提出了一种基于全卷积网络(fully convolutional networks, FCN)的左心室射血分数自动估测的方法.利用全卷积网络对心脏磁共振图像中的左心室进行内轮廓分割,计算心脏左心室在一个心动周期中各时间点的容积,提取左心室舒张末期与收缩末期的容积,最后推导出左心室的射血分数.使用700组图片对全卷积网络进行训练以及440组图片进行测试,并将最后计算结果与美国国立卫生研究院和儿童国家医疗中心提供的射血分数(ejection fraction, EF)金标准进行了对比,计算准确率为89.8%,结果处在合理的误差范围内.     

比索洛尔治疗慢性充血性心力衰竭疗效观察

目的：观察比索洛尔对慢性充血性心力衰竭的临床疗效。方法：80例慢性充血性心力衰竭病人均经心电图、超声心动图和X线胸片确诊,心功能NYHAⅡ～Ⅳ级,LVEF≤45%,随机分为治疗组、对照组各40例。对照组予强心、利尿、血管紧张素转换酶抑制剂等常规治疗,治疗组在常规治疗的基础上加用比索洛尔1.25～10.0mg/d。定期门诊随访,长期坚持服药1年,观察两组治疗前后血液动力学变化及临床治疗效果。结果：治疗组总有效率为97.5%,对照组为75.0%,两组均使充血性心力衰竭患者的心率减慢、心功能改善,超声心动图复查显示左室舒张末期内径缩小,左室射血分数增高,但治疗组明显好于对照组。结论：慢性充血性心力衰竭患者长期坚持使用比索洛尔可使心功能改善,提高生活质量,改善预后。治疗组疗效优于对照组（P〈0.05）。     

46例扩张型心肌病动态心电图分析

目的：探讨扩张型心肌病患者左室射血分数与心律失常的关系。方法：通过对46例扩张型心肌病患者24h动态心电图与心脏彩色多谱勒检查进行分析，研究左室射血分数与心律失常的关系。结果：左室射血分数值越低，复杂型室性心律失常的发生率越高。结论：左室射血分数与室性心律失常联合运用，可作为扩张型心肌病指导治疗、估计预后的良好指标。     

小蘖硷对严重充血性心衰的疗效及其血浆中浓度研究(英文)

用高效液相色谱法研究了小蘖硷浓度对严重充血性心衰的疗效及其血浆中浓度的关系,结果表明：血浆中小蘖硷浓度大于０－１１ｍ ｇ／Ｌ 的患者（ｎ ＝ ３１ ,Ｂ 组） ,其室性早博频率及复杂性的减少和左室射血分数增加比血浆中小蘖硷浓度低于０－１１ ｍｇ／Ｌ（ｎ ＝ ２５ ,Ａ 组） 的患者更为显著。     

硝普钠联合多巴胺治疗急性心力衰竭的疗效与安全性分析

探究硝普钠联合多巴胺治疗急性心力衰竭的疗效与安全性。选取永昌县人民医院收治的108例急性心力衰竭患者作为研究对象,按照随机数字表法分为对照组和观察组,每组54例。对照组采用常规药物硝普钠治疗,观察组采用硝普钠联合多巴胺治疗,观察两组患者治疗效果以及治疗过程中不良反应发生情况。治疗后观察组左心室射血分数、每搏心输出量及6min步行距离均大于对照组(P0.05),且观察组不良反应发生率为3.70%显著低于对照组20.37%(P0.05)。硝普钠联合多巴胺治疗急性心力衰竭临床疗效显著,且不良反应发生率低。     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Density Functional Theory for the Response of Periodic Systems to Electric Fields Based on the Vector Potential Approach

正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that     

On the Thermodynamic Limit for Responses to Static Electromagnetic Fields

For molecular systems,the quantum-mechanical treatment of their responses to static electromagnetic fields usually employs a scalar-potential treatment of the electric field and a vector-potential treatment of the magnetic field.Although the potential for each field separately is associated with the choice of an(unphysical)origin,the precise choice of the origin for the electrostatic field has little consequences for the results.This is different for the     

An affordable accurate evaluation of the binding conformations predicted by molecular docking studies in bio-system

Franck-Condon factors bridge the gap between theoretical modeling and experimental observations for molecular electronic spectroscopy and electron transfer.Under the displaced harmonic oscillator approximation,multidimensional Franck-Condon factors are decomposed into a product of many one-dimensional(1D)Franck-Condon(FC)factors,and each 1D-FC factor is associated with one Huang-Rhys factor that determines the leading contribution of     

Call for Papers

<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with