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1.
In normal baboons cerebrovascular resistance changed along with blood pressure to maintain blood flow constant. This 'autoregulation' was not significantly altered in animals treated with a dose of the calcium channel blocker nimodipine causing selective cerebral vasodilation. 相似文献
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J. D. Lifson E. H. Rubinstein O. U. Scremin R. R. Sonnenschein 《Cellular and molecular life sciences : CMLS》1985,41(4):467-468
Summary Cerebrovascular reactivity to CO2 (CO2R), measured in halothane-anesthetized rabbits, decreased as arterial pressure was increased either pharmacologically or mechanically. On the other hand, hypotension, induced by bleeding, led to an increase in CO2R. These responses were unaffected by denervation of baroreceptors.This work was supported by grants from NIH (HL 17903) and American Heart Association — Greater Los Angeles Affiliate (437IG). To whom requests for reprints should be sent. 相似文献