共查询到20条相似文献,搜索用时 15 毫秒
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-Foetoprotein in normal human serum 总被引:6,自引:0,他引:6
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HL-A antigens on human trophoblast cells 总被引:2,自引:0,他引:2
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Genetics of the human HL-A transplantation system 总被引:6,自引:0,他引:6
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Normal human serum has been known to exert a cytotoxic effect on Trypanosoma brucei subspecies for nearly 80 yr. But in spite of many attempts, no trypanocidal factor was found in human or baboon serum, until Rifkin demostrated a high density lipoprotein (HDL) in normal human serum with trypanocidal activity. The conclusion that this was the trypanocidal factor was supported by the report that serum from patients with Tangier disease, characterised by a severe deficiency of HDL, lacked trypanocidal activity. We report here that Ca2+ is an essential cofactor for the trypanocidal activity of normal human serum, in which alpha2 macroglobulin (alpha 2) might function as a Ca2+-carrier. We further show that D-glucose, D-fructose and D-mannose can suppress the trypanocidal action of normal human serum, whereas glycerol has the opposite effect. 相似文献
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Detection of human leukaemia associated antigens in leukaemic serum and normal embryos 总被引:4,自引:0,他引:4
R Harris D Viza R Todd J Phillips R Sugar R F Jennison G Marriott M H Gleeson 《Nature》1971,233(5321):556-557
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Min Zhang Long Yu Qiang Tu Peirong Hu Qi Zhang Anding Bi Chunling Jiang Shouyuan Zhao 《科学通报(英文版)》1999,44(9):799-799
An EST (gb/AA115239) with high identity to the mouse cytokine signal transduction inhibitor genemmSOCS-2 was selected in GenBank EST database by the homologous screening method. The cDNA with the same sequence of the EST was got
in human placenta cDNA library by PCR and a 1011 bp cDNA fragment was selected using above cDNA as probes to perform walking
hybridization in placenta cDNA library. The cDNA fragment contains one 594 bp open reading frame (ORF) which encodes 198 amino
acid residues. It was proved to be novel after NCBl database screening. Homology comparison showed that this gene has 93%
identity tommSOCS-2 at the amino acid level and it has high identities to other related genes in SH2 domain and SOCS box, so it was namedhumSOCS-2 and the accession number in GenBank is gb/AF020590. The expression analysis showed that the gene is expressed obviously higher
in prostate than in other 15 human tissues. 相似文献
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Urokinase inhibitor in human placenta 总被引:5,自引:0,他引:5
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Properties of horse serum gamma inhibitor 总被引:1,自引:0,他引:1
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