Basal plasma corticosterone level after bilateral selective lesions of the olfactory pathways in the rat

In comparison to control rats, basal plasma corticosterone level and lactacidemia significantly increased in rats submitted to a bilateral lesion of the lateral olfactory tract and/or the anterior branch of the anterior commissure. Only the lesion of the anterior branch of the anterior commissure induced hyperglycemia; that of the lateral olfactory tract exerted an opposite effect.     

Basal plasma corticosterone level after bilateral selective lesions of thee olfactory pathways in the rat

Summary In comparison to control rats, basal plasma corticosterone level and lactacidemia significantly increased in rats submitted to a bilateral lesion of the lateral olfactory tract and/or the anterior branch of the anterior commissure. Only the anterior branch of the anterior commissure induced hyperglycemia; that of the lateral olfactory tract exerted an opposite effect.     

Effects of handling normal and bulbectomized rats at adrenal and plasma corticosterone levels

Summary Normal and bulbectomized adult rats, male and female, handled daily for 4 weeks, show plasma and adrenal corticosterone values significantly lower than the non-handled ones.     

Autoradiographic localization of3H-angiotensin II in rat adrenal glands

Summary Autoradiographic studies of rat adrenal gland approximately 1 min after intra-aortic injection of³H-angiotensin II show that radioactivity concentrates in the zona glomerulosa. This concentration is reduced by concomitant administration of excess unlabelled angiotensin II.     

Diurnal rhythm in the adrenal ascorbic acid concentration of the rat

Zusammenfassung Der tägliche Rhythmus des Ascorbinsäuregehalts in den Nebennieren von Ratten wurde untersucht. Es wurde beobachtet, dass der Ascorbinsäuregehalt um 16 h nachmittags am geringsten ist. Das absolute Gewicht der Nebennieren wiederum ist in der Nacht gegen 24 h am höchsten. Bei praktischen Arbeiten ist dieser Abfall im Ascorbinsäuregehalt der Nebennieren am Nachmittag zu berücksichtigen.

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Aided by a grant from theSigrid Jusélius Stiftelse.     

Adrenal lipid and plasma corticosterone depletion after 7,12-dimethylbenz(a)anthracene administration to the albino rat

Zusammenfassung Fluorometrische Messungen zeigten eine Abnahme von Plasmacorticosterone (CCS). Die Bedeutung dieser Resultate für theoretische Aspekte der Karzinogenese wird diskutiert.     

Circadian rhythm in adrenal adenyl cyclase and corticosterone abolished by medial forebrain bundle transection in the rat

Zusammenfassung Nachweis, dass die Nebennierenrinde von Ratten nicht nur eine rhythmische Tagesschwankung in ihrem Gehalt an Corticosteron, sondern auch eine Schwankung im Gehalt an Adenyl-Cyclase aufweist. Diese Rhythmen können durch eine stereotaktisch ausgeführte Trennung des medianen Vorderhirnbündels, welches zum Hypothalamus führt, aufgehoben werden.

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This work was supported by research grants No. NS-05002 and No. HD-04581 from the National Institutes of Health, USPHS.     

Demonstration of specific receptors for angiotensin III in rat adrenal glands]

Distinct and specific binding sites for 3H-angiotensin II (A II) AND 3H-angiotensin III (A III) have been demonstrated in Rat adrenal gland preparations. A III binding sites have the highest affinity (KD29C1-2.10(-10)M) for the 2-8 heptapeptide. This suggests the possibility of a separate and distinct physiological role for the 2-8 heptapeptide, mediated via such A III binding sites.     

Effects of thyroxine and exercise on the glandular and plasma levels of corticosterone in the male rat

Summary The results presented here demonstrates that the thyroid gland is essential for normal corticosterone production. They further show that exercise stimulates this production whether the thyroid gland is present or not. The release or metabolism of corticosterone seems dependent upon an intact thyroid gland since plasma levels of corticosterone are decreased during exercise if the thyroid is absent. The administration of thyroxine is not sufficient to renew these levels.