Asymmetric distribution of male and female foetuses in the pregnant rabbit uterus

Summary The sex distribution of foetuses in the uterine horn of the pregnant rabbit was found to be asymmetrical, with more males being present in the left uterine horn and more females in the right (p<0.05).     

Distribution and variation of a collagen-degrading enzyme in the uterus of pregnant rats

Zusammenfassung Extrakte aus Uteruswand und Glandula myometralis bauen bei saurem pH Kollagen ab. Die Drüsen haben eine grössere spez. Aktivität. Doch zeigt das Uterusenzym eine grössere Affinität zum Substrat, und seine Gesamtaktivität überwiegt post partum.

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This work was done with the support of the Muscular Dystrophy Association of America to Prof.F. Verzár.     

Distribution of a renin-like enzyme in the bovine adrenal gland

Résumé La glande surrénale bovine contient un enzyme qui réagit avec l'angiotensinogène pour former de l'angiotensine. L'enzyme est distribué dans toute la glande surrénale, en plus grande quantité dans la médullosurrénale et dans la veine centrale. Vu les effects bien connus de l'angiotensine sur la sécrétion de l'aldostérone et sur les catécholamines de la médullosurrénale, il est possible que l'enzyme «rénine-semblable» influence les fonctions spécifiques de la glande surrénale.     

Fatty acids of the pregnant rat uterus

Zusammenfassung Die Untersuchung über die Fettsäure-Zusammensetzung der Ratten-Uteruslipide während der Gravidität ergab ein unverändertes Verbreitungsmuster bei den Hauptfettsäuren der neutralen Lipoide.

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Supported in part by NIH grant No. HD-02599.     

The effect of endotoxin on the lactic acid production in pregnant and non-pregnant rats

Zusammenfassung Die Milchsäureproduktion ist im Knochenmark und in den Leukozyten trächtiger Tiere infolge Endotoxineinwirkung signifikant höher als bei Kontrolltieren. Während sich die Milchsäureproduktion endotoxinbehandelter Plazenten infolge Dauerhemmung der aeroben Glykolyse völlig von allen untersuchten Geweben unterscheidet, bleibt der Sauerstoffverbrauch unverändert.     

Are there cyclic variations in estradiol secretion in the non-pregnant rabbit?

Plasma estradiol-17 beta (E2) concentration was measured in 5 adult non-pregnant rabbits each in 3 different seasons (January, April and September). Blood samples were taken from each rabbit every other day. There was a considerable variation in plasma E2 levels from one sampling day to another, irrespective of the season. The pattern of variation in E2 levels in individual rabbits tended to be cyclic and this cycle was roughly of the order of 8 days. There was no correlation between changes in E2 levels and those in the vaginal appearance.     

Glutathione-related enzyme activities in pregnant rat liver

Summary The levels of GSH-related enzyme activities during pregnancy were determined. A significant increase in Selenium-dependent GSH peroxidase and GSH S-transferase E activity was observed. A concomitant increase in -glutamylcysteine synthetase was measured, which indicated an increased ability to synthesize the tripeptide.     

Glutathione-related enzyme activities in pregnant rat liver

The levels of GSH-related enzyme activities during pregnancy were determined. A significant increase in Selenium-dependent GSH peroxidase and GSH S-transferase E activity was observed. A concomitant increase in gamma-glutamylcysteine synthetase was measured, which indicated an increased ability to synthesize the tripeptide.     

In vivo and in vitro incorporation of 3H-thymidine in the uterus of the rabbit during pseudopregnancy

During pseudopregnancy in the Rabbit the DNA synthesis in the uterine epithelium is very reduced. These results conjoined with the decrease of the mitotic index and previous ultrastructural observations allow to think that multinucleated cells proceed mainly by cell fusion.     

Effect of decapacitation factor on the oxygen uptake of rabbit spermatozoa recovered from the uterus

Résumé L'addition d'un facteur de décapacitation préparé à partir du plasma séminal de lapin et de taureau a généralement produit une augmentation supplémentaire de l'absorption d'oxygène, quand il a été ajouté à la suspension de spermatozoïdes enlevée de l'utérus. Le facteur de décapacitation n'a exercé aucun effet stimulant similaire sur les spermatozoïdes de lapin avant l'incubation dans l'utérus et n'a montré lui-même aucune absorption d'oxygène appréciable.

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Dr.I. G. White is indebted to the Population Council for a fellowship and to the Australian Research Grants Committee for financial support. The authors are indebted to ProfessorC. W. Emmens for his interest and advice.     

Effects of female sex hormones on polyamine-oxidizing enzyme activities and polyamine concentrations in immature rat uterus and liver

17-estradiol (E₂) and progesterone (P) treatment of immature female rats (10 g/100 g body weight) respectively resulted in 1.38-fold (p<0.02) and 1.42-fold (p<0.02) increase in the uterine polyamine oxidase activity, and 2.45-fold (p<0.001) and 1.43-fold (p<0.02) increase in the uterine diamine oxidase activity, as compared to the controls. E₂ caused a 5-fold (p<0.05) and a 1.36-fold (p<0.05) increase in putrescine and spermidine concentration respectively in rat uterus. Increases of 1.7-fold (p<0.02) and 1.6-fold (p<0.05) in putrescine and spermine concentration were determined in the P-treated uterus, as compared to the controls. The spermidine/spermine ratio, which is regarded as an index of growth rate, was higher in the E₂-treated uterus and lower in the P-treated uterus than in the control uterus. No statistically significant hormonal effects were estimated in the immature liver. The data reported suggest the possibility of an involvement of polyamine-oxidizing enzymes in the modulation of polyamine concentrations in rat uterus by the female sex hormones.     

Antihypertensive effect of purified enzyme showing angiotensinase activity from rabbit red cells in rats

Zusammenfassung In der akuten Phase der Goldblatt-Hypertonie der Ratte verhinderte die Injektion von reiner Angiotensinase ein Aussteigen des Blutdruckes. Die Behandlung war unwirksam bei chronischem Hochdruck.