Über die Wirkung von Mischungen eines antigenhaltigen Plasmas mit einem antikörperhaltigen Serum auf die Entwicklung des Fremdkörpergranuloms

Summary It has been shown that local application of a mixture of precipitating antiserum with homologous plasma or serum promotes markedly the growth of granuloma tissue in the rat.     

Über die Auslösung der Fluchtreaktion bei Fliegen

Summary Contrary toGaffron, 1934, it has been shown that when flies flee from the catching hand, this reaction is merely due to optical stimuli (experiments with flies behind glass). Air movements play no part in this connection (experiments with blinded flies).     

Über die Wirkung von Elastase auf die Blutgerinnung

Summary Purified elastase prepared by adsorption on synthetic zeolite in proper concentrations causes the coagulation of blood. Elastase was found to have no direct coagulative action on purified fibrinogen. Its coagulating action is due to the fact that it reacts with prothrombin to form thrombin. The reaction between prothrombin and elastase is independent of the presence of either platelets, thromboplastin or Ca-ions.     

Die Wirkung von synthetischen Antihistaminkörpern auf die Senfölchemosis am Kaninchenauge

Summary Intravenous or subcutaneous administration of pyribenzamine and other antihistaminics is able to decrease, and to delay the appearance of chemosis produced by mustard oils in the eye of the rabbit. Simultaneously occurring vascular reactions, on the other hand, are but slightly affected by antihistaminics. Intravenous or subcutaneous administration of rutin has no clear-cut effect on chemosis; it is however able to inhibit the vascular reaction.     

über die Wirkung des Kohlenoxyds auf Atmung und Ionenaufnahme von Weizenwurzeln

Summary The effect of carbon monoxide upon oxygen consumption and ion absorption in wheat roots has been studied. In the dark, inhibition of respiration by CO (in sufficiently high concentrations) is nearly as great as the maximum inhibition in cyanide. Similarly, the chloride absorption is strongly inhibited. Inhibition of respiration and ion absorption by CO is light-reversible.     

Über die Wirkung von Cobalt-II-nitrat auf Kern und Cytoplasma vonAcetabularia mediterranea

Summary The effect of Cobalt-II-nitrate was tested on the marine green algaAcetabularia. Application of Co immediately stopped regeneration as well as synthesis of cytoplasmic proteins. Later on a decrease of the protein contents was observed. Without affecting the size of the nucleus, Co caused a reduction of the nucleolar size and shape within 4 days. By histochemical methods, Co was found to be stored in the nucleus and nucleolus. However, it is not clear whether the Co was already boundin vivo. Size and distribution of the polyphosphate bodies were not changed within 6 days. No storage of Coin vivo could be observed within the polyphosphates.

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Mit Unterstützung durch die Deutsche Forschungsgemeinschaft.     

Die Wirkung von Kalzium und Serum auf die Wanderung von zitratgeschädigten menschlichen Leukozyten

Summary In the inhibition of the migration of human leucocytes by tribasic sodium citrate conditions are similar to those in the inhibition of phagocytosis directed againstE. coli. At least two elements important for the migration are inactivated by citrate: (1) the free calcium ions, (2) serum factors whose nature is yet unclear. The inhibition of the migration of leucocytes by sodium citrate is reversible. Leucocytes inhibited by citrate acquire full capacity to migrate again after addition of calcium ions and serum factor.     

Über die Wirkung von Pyribenzamin und anderen Antihistaminika auf die durch Histaminverabreichung erzeugten Magenulzera

Summary Ulcers of the stomac of guinea-pigs, produced by subcutaneous application of histamine, are reduced to a significant degree in number by peroral application of antihistaminics. The effect is corresponding to the given dosage. Pyribenzamin proved to be the most effective.     

Über die Wirkung von Phenylbutazon auf den Tricarbonsäurezyklus und andere Fermentsysteme

Summary Cholinesterase, hyaluronidase, chondroïtinase and -glucuronidase are not inhibited by phenylbutazone in concentrations up to 10^–3 M.Phenylbutazone accelerates the oxidation of the acids of the Krebs cycle in therapeutic concentrations up to 10 mg%; in higher concentrations it acts as an inhibitor. The inhibition of the -keto acid oxidation begins at lower concentrations of phenylbutazone then for the other intermediates.     

Die katalytische Wirkung von Metallionen auf die Stabilität von Phosphagenen

Summary Phosphoroguanidates, a class of compounds which includes the enzymatically-active phosphagens, exhibit exceptionalin vitro stability. This lack of reactivity implies anin vivo mode of activation, as yet undiscerned. A variety of metal ions catalyse the cleavage of the phosphorus-nitrogen bond with consequent phosphoryl-group transfer, but the enhancement of rate seems insufficient to account for the known activities of phosphoro-creatine and phosphoro-arginine. It is suggested that yet another mode of activation, chemical or biochemical, awaits discovery.     

Über die Wirkung von Phenanthrenchinon (9, 10) und einer wasserlöslichen Transportform auf Glykolyse und Atmung des Ascites-Tumor

Summary Phenanthrenchinon (9, 10) and hydrochinon-bis-glycylester prepared as water-soluble transportform, are strong inhibitors of glycolysis. Glycolysing cells are depleted from ATP in a few minutes.     

Notiz über die unterschiedliche Wirkung der Schallabsorption auf den Klang von neuen und alten Geigen

Summary The Theory of Residue explains how the absorption of high frequency harmonicschanges the tone quality and loudness of old violins less than that of modern ones. Indeed, following this theory, the high frequency harmonic components directly contribute to the sensation of fundamental sound. Therefore in new violins, rich in high partial components, the room absorption makes itself felt not only in these, but also in the fundamental component sensation.     

Wirkung von Polysacchariden bakterieller Herkunft auf die experimentelle Lipämie

Summary Polysaccharide fractions derived from a gram-negative proteus organism show strong anti-lipaemic activity of the order of 1000 times that of heparin. Analogous preparations from gram-positive organisms and mycobacteria show no such activity and some polysaccharide fractions from plant and animal tissues proved to have slight activity. None of these polysaccharides influenced the clotting of plasmain vitro.     

Über die bakteriostatische Wirkung von Anthocyanen und verwandten Stoffen

Summary Some anthocyanins and flavonols have been found to have no bacteriostatic effect on pathogenic micro-organisms.     

Wirkung der Adrenalektomie und Desoxycorticosteronbehandlung auf die Ascorbinämie und Ascorbinurie der Katze

Summary Two cats were adrenalectomized and kept healthy with daily injections of desoxycorticosterone acetate. The ascorbic acid concentration of blood and urine remained the same as in normal controls. When Dexoxy-corticosterone was omitted, a crisis ensued but the blood and urine concentration of ascorbic acid did not decrease.     

Über die Gestalt von Fadenmolekülen in Lösung

Summary Some arguments put forward byG. Bier in a recent article in order to supportH. Staudinger's assumption that chain molecules in solution should behave like straight rigid rods are examined. It is shown that the assumptions made byG. Bier are largely arbitrary. The main argument is the assumption that the C-C-bond in long chain molecules should not show any rotation. As far as this point is concerned, attention is drawn to some recent publications showing that the viscosity of shape of chain molecules can be determined by experiment (specific viscosity and double refraction of flow at high velocity gradients). According to these determinations the time necessary for a complete change of shape, using partially free rotation, is of the order of 10^–5–10^–3 seconds for molecules like nitrocellulose or polystyrene up to degrees of polymerization of several thousands and for viscosities of the solvent of the order of 10^–2 poises.     

Vergleichende Untersuchungen über die hypertensive Wirkung von Aldosteron und Desoxycorticosteron

Summary In the adrenalectomized and unilaterally nephrectomized rat an investigation has been carried out on the influence of a four weeks' treatment with aldosterone and desoxycorticosterone-acetate in doses which are equieffective concerning sodium retaining capacity. Desoxycorticosterone-acetate produced hypertension, perivascular granuloma and renal lesions, whereas under the influence of aldosterone the blood pressure remained normal and no histopathological alterations could be found. Towards the end of the experiment the animals treated with desoxycorticosterone-acetate took up twice as much drinking fluid as the animals treated with aldosterone. Although the results obtained so far are only of a preliminary character it is obvious that aldosterone in doses which are equieffective concerning sodium retention does not produce the same side effects as desoxycorticosterone-acetate.     

Über den Einfluß von Oxytocin und Vasopressin auf die Ausscheidung von Kalium und Natrium durch die Niere

Summary In decisive experiments on diuresis with rats it is shown that oxytocin and vasopressin have a contrary effect on the excretion of Na and K. Oxytocin increases the excretion of Na, vasopressin decreases the excretion of Na and raises the excretion of K. The effects on Cl-and water-metabolism may be considered only as consequences of the primary effect on Na and K.     

Der Einfluß von Aneurin und Cholin auf die Spaltung von Tributyrin durch Serum und Erythrocyten

Ohne Zusammenfassung