水溶液中Fe^3＋与胆固醇的作用

采用ＩＣＰ发射光谱法测定了在不同的条件下胆固醇在溶液中对Ｆｅ３＋的吸附情况，得出胆固醇与Ｆｅ３＋相互作用的关系，并就Ｆｅ３＋与高胆固醇血症的关系进行了讨论，得出了一些有意义的结果．     

水溶液中Cu^2＋与胆固醇的相互作用

用双乙醛草酰二腙分光光度法测定了在不同条件下，胆固醇在水溶液中对Ｃｕ＾２＋的吸附情况，得出胆固醇与Ｃｕ＾２＋相互作用属物理吸附的关系，并就ＣＵ＾２＋与高胆固醇血症的关系进行了讨论。     

高脂蛋白血症和动脉粥样硬化:饮食治疗

如见于高胆固醇血症和/或高甘油三酯血症的血浆低密度脂蛋白和/或极低密度脂蛋白水平的提高主要是由于饱和脂、高胆固醇、高热量饮食和过量饮酒所引起。饮食治疗是构成成功地处理高脂血症的基本步骤。即使原发型高脂蛋白血症病人,适当设计的饮食也可以把这个问题减轻到可变程度。当血清胆固醇成人高于200mg/dl,小孩190～200mg/dl,和有甘油三脂值持续大于200m     

高脂血症与膳食关系36例分析探讨

血浆脂质中一种或多种成份的浓度超过正常高限时称高脂血症，因血浆脂质为脂溶性，必须与蛋白质结合为水溶性复合物而运转全身，政高脂血症常表现为高脂蛋白血症．作者从1992年5月至1997年5月，研究分析36例高脂血症患者，发现本病和膳食密切有关，现报道如下。1．临床资料本组36例，男性26例，女性10例，年龄范围30－55岁，平均42岁．血脂测定：胆固醇均＞220mg／100Inl，甘油三酯＞160mg／100thl。分别称为高胆固醇血症和高甘油三酯血症，统称树油症．有遗传因素的6例，其父母也有高脂血症．吸烟者：男性22例，女性2例；男性病人均嗜酒。…     

我院中老年教职工血脂调查报告

本文对595名40岁以上知识分子的血清胆固醇和甘油三酯进行了调查统计,其中31人为高胆固醇血症,占5.2％,104人为高甘油三酯血症,占17.5％,30人为混合型高脂血症,占5％。高脂血症的发病率有随年龄增高而增高趋势,且女性高于男性。     

辛伐他汀治疗高胆固醇血症小鼠过程中肝脏的差异表达基因

为了研究辛伐他汀治疗高胆固醇血症过程中肝脏的差异表达基因,我们利用抑制消减杂交(SSH)技术构建了高胆固醇血症小鼠及高胆固醇血症经辛伐他汀治疗小鼠的肝脏双向差异表达基因文库,并采用改进的negative subtraction chain(NSC)方法去除正向文库的绝大部分假阳性背景,使得SSH文库的容量缩小了近50倍,对筛选到14个差异表达克隆再经过斑点杂交验证,最终获得8个阳性克隆.经DNA序列测定和基因功能分析,结果表明,辛伐他汀治疗高胆固醇血症过程中,小鼠肝脏差异表达的已知功能基因主要有以下几类:脂类代谢基因、炎性免疫反应相关基因、细胞粘附基因、逆境胁迫基因.改进的NSC和SSH技术的结合使用,大大地增加了差异表达基因文库的阳性率,提高了获得差异表达基因的效率.     

525例伴血脂异常IgA肾病患者的临床病理分析

目的:探究不同血脂类型的IgA肾病患者的临床病理表现的差异.方法:采用横断面研究设计,纳入525例IgA肾病患者的性别、基线年龄、基线病程、基线血压、高血压病史、血肌酐、eGFR、尿酸、24 h小时尿蛋白定量、尿红细胞计数、血清白蛋白、血脂、Katafuchi半定量病理积分系统(包括小球积分、小管-间质积分、血管积分)等临床病理资料,根据血脂结果将患者分为血脂正常组、高胆固醇血症组、高甘油三酯血症组、低高密度脂蛋白组,分别比较各组临床病理指标的差异.结果:高甘油三酯血症组的间质纤维化积分、小管萎缩积分、小管间质积分、血管壁增厚积分、血管积分、katafuchi总积分高于血脂正常组;其小球增殖积分低于高胆固醇血症组;而血管壁增厚积分高于高胆固醇血症组.结论:不同血脂异常类型的IgA肾病患者的病理损害程度并不完全相同,其中高甘油三酯血症可能对肾脏病理改变影响较大.     

我校45岁以上脑力劳动者血脂水平调查

校医院对我校45岁以上508名脑力劳动者进行了血脂水平的调查。检出胆固醇与β-脂蛋白正常者318人,异常者190人。测定出受检人群的血脂正常值水平:血清胆固醇正常值男性4.55±0.0884mmol/L,女性4.65±0.130mol/L;血清β-脂蛋白正常值男性5.00±0.125g/L,女性5.08±0.215g/L。临床检测指标规定40岁以上血清胆固醇高于6.5mmol/L 者为高胆固醇血症。我校受检的508人中高胆固醇血症者     

高脂蛋白血症

<正> 按世界卫生组织一九七○年所下的定义,高脂旦白血症系指一种或几种脂旦白在血浆中浓度增高如高乳糜微粒血症、高极低密度脂旦白血症、高中密度脂旦白血症及高低密度脂旦白血症,同时它伴有血清脂质浓度的增加如高胆固醇血症及高甘油三酯血症。至于高脂血症则成为一般术语,泛指血浆极低密度脂旦白或乳糜微粒浓度增高,致使血浆甘油三酯浓度增高血浆呈混浊而言。高脂旦白血症分为五型,其中Ⅱ型分为二个亚型。     

戊糖片球菌改善高脂饮食小鼠肠道菌群机制研究

为了探究具有降胆固醇能力的肠道微生物对高脂饮食引起的高胆固醇血症的作用,本研究从人体粪便中分离出具有高效降胆固醇能力且耐胃蛋白酶、胰蛋白酶、胆盐的肠道微生物．选取优势肠道微生物进行菌种鉴定后进行小鼠实验,测定小鼠的体质量、脏器系数、肝脏及粪便的胆固醇含量,研究其降胆固醇作用．实验筛选获得具有较强降胆固醇能力的肠道微生物P4,经鉴定为戊糖片球菌(Pediococcuspentosaceus),其能够抑制高脂饮食诱导的小鼠血清中胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)的升高,降低肝脏和粪便中的胆固醇及血清中的高密度脂蛋白胆固醇(HDL-C),从而达到降血脂的目的．通过高通量测序实验分析了小鼠肠道的菌群组成,发现戊糖片球菌P4能够通过改善肠道微生物的组成和丰度降低小鼠肠道中厚壁菌门(Firmicutes)与拟杆菌门(Bacteroidetes)的比值,改善由小鼠高脂饮食引起的高胆固醇血症．因此,筛选出的戊糖片球菌P4对降胆固醇功能产品的研究开发具有重要意义.     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Density Functional Theory for the Response of Periodic Systems to Electric Fields Based on the Vector Potential Approach

正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that     

On the Thermodynamic Limit for Responses to Static Electromagnetic Fields

For molecular systems,the quantum-mechanical treatment of their responses to static electromagnetic fields usually employs a scalar-potential treatment of the electric field and a vector-potential treatment of the magnetic field.Although the potential for each field separately is associated with the choice of an(unphysical)origin,the precise choice of the origin for the electrostatic field has little consequences for the results.This is different for the     

An affordable accurate evaluation of the binding conformations predicted by molecular docking studies in bio-system

Franck-Condon factors bridge the gap between theoretical modeling and experimental observations for molecular electronic spectroscopy and electron transfer.Under the displaced harmonic oscillator approximation,multidimensional Franck-Condon factors are decomposed into a product of many one-dimensional(1D)Franck-Condon(FC)factors,and each 1D-FC factor is associated with one Huang-Rhys factor that determines the leading contribution of     

Call for Papers

<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with