共查询到20条相似文献,搜索用时 15 毫秒
1.
H. P. Striebel 《Cellular and molecular life sciences : CMLS》1976,32(4):457-458
Summary 4-isothiocyanato-4-nitrodiphenylamine was found to possess activity against intestinal nematodes in mice, against schistosomes in various hosts including primates and against two filarial species in the mongolian jird. Upon administration in a single oral dose it is equally effective againstS. haematobium, S. mansoni andS. japonicum. 相似文献
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Summary Several 4, 5-unsaturated adenine nucleosides were shown to have antiproliferative activity against L 1210 leukemia cells in vitro. The active nucleosides were cytotoxic to the L 1210 cells as demonstrated by Trypan Blue uptake. The cytotoxicity was not induced by alterations in the ribonucleoside and deoxyribonucleoside triphosphate levels of the L 1210 cells. 相似文献
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Zusammenfassung An Glukorons?ure gebundenes 1-(3′-Methoxy-4′-hydroxy-phenyl)-6, 7-dimethoxy-chinolin ist als Metabolit des Papaverins beim
Menschen und bei S?ugetieren erkannt und isoliert worden. Ein in den Lebermikrosomen enthaltenes Ferment, dassauerstoff-und
TPNH-abh?ngig ist, bewirkt die Methoxylspaltung, und ein weiteres Ferment übertr?gt die Glukurons?ure aus ihrer Verbindung
mit Uridinphosphat auf die entstandene phenolische Verbindung.
相似文献
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M. Okabe T. Adachi Y. Kohama T. Mimura 《Cellular and molecular life sciences : CMLS》1986,42(4):398-399
Summary The fertilization ratio of mouse ova in vitro decreased when glucose concentration in the medium was lowered. However, the addition of phloretin-2--D-glucose (phloridzin), known as a glucose uptake inhibitor, restored the fertilization ratio back to the control level. The glucose moiety of the phloridzin seemed to be responsible for this effect. 相似文献
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P. J. Chan 《Cellular and molecular life sciences : CMLS》1987,43(8):929-930
Summary The in vitro development and attachment of hatched mouse blastocysts on the untreated substratum was enhanced by 10 M dibutyryl cCMP (dbcCMP). The result suggests that cCMP has an effect on embryonic development and on the blastocyst attachment process.25 November1986 相似文献
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OU XiuQin XU ShengZhao LIANG GuangChuan WANG Li & ZHAO Xia Institute of Power Source & Ecomaterials Science Hebei University of Technology Tianjin China 《中国科学:技术科学》2010,(4)
Lithium iron phosphate(LiFePO4)was synthesized from LiOH,FeSO4 and H3PO4 by a hydrothermal process at 180℃.The samples were characterized by X-ray diffraction,scanning electron microscopy and chemical analysis.Electrochemical performance of the samples was tested in terms of charge-discharge capacity and cycling behavior.The results indicated that Fe(Ⅲ) impurity had obviously effect on the electrochemical properties of LiFePO4,and the formation of Fe 3+ was caused by the oxidation of Fe 2+ in the dissolving... 相似文献
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M. D. Reuber 《Cellular and molecular life sciences : CMLS》1976,32(2):218-219
Summary Buffalo strain male rats, 12 weeks of age, ingesting 0.04% N-4-(4-fluorobiphenyl)acetamide in a semisynthetic diet with both kidneys intact were more susceptible to the development of hyperplasia and carcinomas of the kidney than were rats with a uninephrectomy. 相似文献
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E. Arrigoni-Martelli C. Kaergaard Nielsen U. Bang Olsen H. J. Petersen 《Cellular and molecular life sciences : CMLS》1980,36(4):445-447
Summary N-cyano-N-4-pyridyl-N-1,2,2-trimethylpropylguanidine, monohydrate (P 1134) is a new agent which induces a marked and sustained hypotensive response in normotensive and renal, neurogenic, and spontaneously hypertensive rats, as well as in normotensive and renal hypertensive dogs. The overall potency of this compound is 2–3 times greater than that of hydralazine. The fall of blood pressure is accompanied by an increase in heart rate and cardiac output and a decrease in total peripheral resistance. The hypotensive effect appears to be due primarily to a direct relaxant effect on vascular smooth muscle.Acknowledgment. The helpful comments and advice of Dr W.O. Godtfredsen are greatefully acknowledged. 相似文献
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L. J. Corcuera C. B. Queirolo V. H. Argandoña 《Cellular and molecular life sciences : CMLS》1985,41(4):514-516
Summary 2--Glucosyl-4-hydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA-Glc), the main hydroxamic acid from maize and wheat, and its aglucone, decreased survival ofSchizaphis graminum reared on artificial diets. Both compounds were toxic for aphids and acted as feeding deterrents, at concentrations as low as 1 mM. The natural concentrations of glucosides of hydroxamic acids in wheat leaves reach up to 6 mmoles/kg fresh weight, thus falling within the range in which DIMBOA-Glc causes delecterious effects to diet-fed aphids.To whom correspondence should be addressed. THis work was supported by grants from International Foundation for Science (484), Universidad de Chile (N-1654) and the Agency for International Development. 相似文献
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J. N. Bach J. T. McLaughlin R. R. Sonnenschein 《Cellular and molecular life sciences : CMLS》1961,17(12):568-569
Zusammenfassung Paraoxon beeinflusst die Wirkung von-Lobelin über den Axonreflex, der Schwitzen menschlicher Haut auslöst. Geringe Konzentrationen von-Lobelin werden durch Paraoxon verstärkt, während höhere gehemmt werden. Daraus wird gefolgert, dass endogenes Acetylcholin an der Auslösung des Axonreflexes beteiligt sein kann. 相似文献
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B. J. Clarris 《Cellular and molecular life sciences : CMLS》1982,38(3):350-351
Summary In medium supplemented with serum, PGE1 and PGE2 were equally potent in inducing cells with a fenestrated appearance, whereas PGF2 was comparatively ineffective. In BSA without serum the effects were more persistent and characterized by a high proportion of astrocyte-like cells. The effects were reversed upon removal of the prostaglandins.This work was supported by the National Health and Medical Research Council of Australia. 相似文献
13.
Aln (n = 3, 4, 6, 13, 19)团簇的结构稳定性与形态演化 总被引:1,自引:0,他引:1
采用第一原理赝势平面波方法, 计算了不同结构形态Aln (n = 3, 4, 6, 13, 19)团簇的几何与电子结构, 通过结合能与HOMO-LUMO能隙表征和分析了其结构稳定性, 采用线性同步转变 (LST)方法考察了其不同结构形态间的演化与转 变. 结果表明: Al3, Al4, Al6, Al13和Al19团簇的稳定结构形态分别为三角形、 菱形、八面体、二十面体、双二十面体. Al3, Al4与Al13团簇不存在亚稳结构. Al6与Al19团簇存在亚稳结构, 其结构形态分别为平行四边形与八面体. Al6团簇亚稳结构与稳定结构的能级差大、转变能垒低, 结构转变容易, 亚稳结构稳定性差. 而Al19团簇亚稳结构与稳定结构的能级差小、转变能垒高, 结构演化不易, 因而实验和理论模拟中能观察到其亚稳结构形态——正八面体的存在. 相似文献
14.
Melvin Cohn 《Cellular and molecular life sciences : CMLS》2014,71(11):2033-2045
The existence of antigen-receptors, BCR, and T cell antigen-receptors, that are “polyreactive”, necessitates a rethinking of its effect on two problems faced by the “adaptive” immune system: the self (S)–nonself (NS) discrimination and the determination of effector class. Here, we will concentrate on the impact of polyreactivity on the S–NS discrimination. The anti-S cells interacting with S (i.e., responding to Signal 1) are on the pathway to inactivation. Before irreversibility sets in, these cells can be activated by a second signal (Signal 2) from an effector T-helper (eTh). As these polyreactive anti-S cells express anti-NS specificities, they can be activated by recognition of NS-epitopes in the host’s normal immunogenic load with the potential to result in autoimmunity. This problem is delineated using a discrete structural model, the corollaries of which are: (1) a two-step pathway for the purging of anti-S cells (i.e., the S–NS discrimination), and (2) defensible contexts within which to view the phenomena of receptor editing, anergy, and dual receptor cells. 相似文献
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《Cellular and molecular life sciences : CMLS》1991,47(8):827-828
Science Policy News
The Second VDI-International Conference on Effects of Atmospheric Precipitations on Soils: Uptake, Assessment and Regulation (Lindau, Germany, 15–17 May 1990) 相似文献16.
《Studies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics》2009,40(4):374-382
In this paper, we discuss various aspects of Heisenberg's thought on hidden variables in the period 1927–1935. We also compare Heisenberg's approach to others current at the time, specifically that embodied by von Neumann's impossibility proof, but also views expressed mainly in correspondence by Pauli and by Schrödinger. We shall base ourselves mostly on published and unpublished materials that are known but little-studied, among others Heisenberg's own draft response to the EPR paper. Our aim will be not only to clarify Heisenberg's thought on the hidden-variables question, but in part also to clarify how this question was understood more generally at the time. 相似文献
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J. R. Pasqualini 《Cellular and molecular life sciences : CMLS》1963,19(12):657-658
Résumé Le 3, 17, 21-trihydroxy 5-pregnane (allo-tétrahydro-17-hydroxy-cortexone) et le 3,21-dihydroxy 5-prégane (allo-tétrahydro-cortexone) ont été identifiés dans l'urine humaine. Ces composés avaient les mêmes migrations chromatographiques avant ou après acétylation ou oxydation que les respectifs stéroïdes de synthèse. 相似文献
20.
本文研究了熔体快淬工艺及添加元素Ti对Sm-Fe合金相的形成及结构的影响,成功制备了Sm3(Fe,Ti)29Nx/α-Fe双相纳米耦合永磁材料。研究发现,快淬薄带由Sm3(Fe,Ti)29和α-Fe两相组成,晶化前在纳米晶周围存在部分非晶相,晶化后的晶粒间晶界平直光滑、且晶粒间结合紧密没有界面相,为晶粒间直接接触耦合。对甩带后的样品采用750℃保温10min的晶化退火得到的颗粒比较细小且均匀。氮化磁粉磁滞回线的第二象限没有出现明显的台阶,表现为单相永磁材料的特点,说明硬磁相Sm3(Fe,Ti)29Nx与软磁相a-Fe晶粒之间的交换耦合作用已形成。 相似文献