Cardiac pressoreceptors in rat

Resumen Se describe la probable existencia de presorreceptores en el ventriculo izquierdo de la rata. La vía aferente de este reflejo sería el vago y la eferente el simpático. El centro o alguna conexión neuronal estaría a nivel del bulbo raquídeo.     

Antigenic correlation between rat brain synaptic vesicles and rat bone marrow B lymphocytes

Summary Rabbit anti-rat brain synaptic vesicle serum reacted with thymocytes and B lymphocytes in cytotoxicity and immunofluorescence assays. Quantitative absorption analysis revealed that this antiserum contained antibodies specific for antigenic determinants on the surface membrane of a subpopulation of rat bone marrow B lymphocytes.This work was supported by the Republic of Serbia Research Fund, Belgrade.     

The effect of pretreatment with rat placental homogenate on subsequent pregnancy in the rat

Résumé L'effet d'un traitement immunologique sur la grossesse du rat a été étudié. Les animaux du groupe expérimental ont reçu 8 injections d'homogénat placentaire à raison de deux par mois, puis ont été accouplés. Après 21 jours de grossesse il y avait moins de fétus nés vivants que dans le groupe témoins non-traité; le poids des fétus en vie était en général normal mais on a noté une augmentation significative de la masse placentaire par rapport au groupe témoin.     

Antigen-distribution in rat liver mitochondria

Riassunto I mitocondri di fegato di ratto possiedono almeno tre gruppi di antigeni, dei quali uno è esclusivamente legato alle membrane mitocondriali, uno è presente nella frazione solubile in 0,3% desossicolato di sodio ed un altro, che, sebbene principalmente localizzato nelle membrane, è anche dimostrabile nella frazione desossicolato solubile.     

Mast-cell heterogeneity in the rat

Summary In the rat, O-hydroxy ethyl rutoside derivatives release histamine and serotonin from skin mast-cells, but not from peritoneal mast-cells. These cellular populations do not exhibit identical pharmacological properties.     

Antigenic correlation between rat brain synaptic vesicles and rat bone marrow B lymphocytes.

Rabbit anti-rat brain synaptic vesicle serum reacted with thymocytes and B lymphocytes in cytotoxicity and immunofluorescence assays. Quantitative absorption analysis revealed that this antiserum contained antibodies specific for antigenic determinants on the surface membrane of a subpopulation of rat bone marrow B lymphocytes.     

Visual input to rat pineal

Summary Electrophysiological recordings from freely behaving rats, previously implanted stereotaxically with permanent electrodes in the pineal, ventromedial hypothalamus, caudate nucleus, lateral geniculate body and medial geniculate body were obtained. The pineal photic responses revealed 5 sequential components. Injection of a neuronal blocker at the level of the superior cervical ganglion did not alter the earlier photic responses, but did eliminate the late components (N₂–P₃) for 60–90 min after the injection. All of the other responses were unchanged during the experiment. The present experiments demonstrated that photic input travels to the pineal through two pathways.The author is grateful to Dr C.M. Prashad and Ms. Marjorie Brown for technical assistance. Supported in part by grant NS 16596.     

Clofibrate-induced myotonia in the rat

Summary Clofibrate induced electromyographic and contractile responses in rats consistent with myotonia.This work was supported in part by the Muscular Dystrophy Associations of America. The authors are grateful to Ayerst Laboratories for the generous supply of clofibrate used in this study.     

Hypoxic tachycardia in the rat

Summary Awake, freely breathing rats subjected to moderate hypoxia (10% O₂) manifest prompt tachycardia which is essentially unaffected by atropine and is blocked by propranolol, and is thus apparently mainly of sympathetic origin.This work was supported by grants from American Heart Association — Greater Los Angeles Affiliate (437IG), and National Science Foundation (GB-41390). J. D. L. was a Summer Scholar selected by the Committee for Advance Science Training. We thank Mr D. Ward and Miss L. J. Berg for much valuable assistance and Dr. J. L. Kinney for help in the statistical analysis of the data.     

Ultracentrifugation of rat intestinal mucosa

Résumé Nous avons présenté une méthode de fractionnement et d'isolement des particules subcellulaires de la muqueuse intestinale du rat. L'héparine permit l'isolement de fractions relativement homogènes.

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This work was supported by USPH Grant No. 5 T 1 HD-18-04, Child Health and Human Development Branch.     

Cholecystokinin-induced hypothermia in the rat

Summary Cholecystokinin-octapeptide (CCK-8) was shown to cause hypothermia after intracerebroventricular administration in the rat, and the hypothermic effect of CCK-8 was antagonized by simultaneous injection of TRH.     

Choline accumulation in isolated rat hepatocytes

Summary The accumulation of non-metabolized choline in isolated rat hepatocytes is concentrative in Na⁺ medium, whereas the accumulation does not exceed unity in a Li⁺ medium. Ouabain and 2,4-dinitrophenol inhibited the choline uptake. These results indicate that choline is taken up by rat hepatocytes via a Na⁺-and energy-dependent process, and choline oxidase is not directly connected with the choline transport system.     

Polyhydroxylated metabolites oftrans-stilbene in the rat

Zusammenfassung Nach Eingabe vontrans-Stilben bei Ratten wurden die grössten Mengen im Harn als 3,4,4-Trihydroxystilben, 3,4,4-Trihydroxybibenzyl und 3,3, 4,4-Tetrahydroxybibenzyl nachgewiesen. Die Bibenzylderivate werden nachscheinlich nach Ausscheidung in der Galle von Darmbakterien metabolisiert.