Fucosidosis and blood group substances in the urine]

Glycopeptide and oligosaccharide fractions obtained from fucosidosis urine contains more Lea activity (4-8 fold) than control urine. Both fucosidosis fractions also contained Leb and H activities, no A activity in contrast to the salivary and erythrocyte phenotypes (A, Le a+ b-). The amount of Leb activity is lower in both fractions (1) and (2) than that of Leb control children (4-16 fold decrease). Blood group A activity was not detected at any concentration used (less than or equal to 50 fold-concentrated urine) whereas A activity was found in (A, Le a- b+) control urine. On the contrary, both fucosidosis fractions contained H activity, whereas A (Le a- b+) control children fractions had none (less than or equal to 50-fold concentrated urine). H and Leb activity might originate from Lea precursor apart from the "non-secretory" type of the patient.     

Pseudomonas lectin PA-I detects hybrid product of blood group AB genes in saliva

Pseudomonas aeruginosa galactophilic lectin PA-I exhibits an outstanding affinity for soluble hybrid oligosaccharide products of human A and B genes in saliva of heterozygous AB individuals. Neither A nor B salivas, nor an artificial mixture of them, inhibit PA-I hemagglutinating activity to the same extent as saliva from heterozygotes. Other lectins examined do not exhibit this property.     

Pseudomonas lectin PA-I detects hybrid product of blood group AB genes in saliva

Summary Pseudomonas aeruginosa galactophilic lectin PA-I exhibits an outstanding affinity for soluble hybrid oligosaccharide products of human A and B genes in saliva of heterozygous AB individuals. Neither A nor B salivas, nor an artificial mixture of them, inhibit PA-I hemagglutinating activity to the same extent as saliva from heterozygotes. Other lectins examined do not exhibit this property.     

No association between Gilbert's syndrome,the AB0 blood groups and the haptoglobin phenotypes

Summary The different AB0 blood groups and haptoglobin phenotypes are as frequent in a well-defined group of subjects with Gilbert's syndrome as in appropriate samples of the general population.Acknowledgments. The haptoglobin phenotype determinations were kindly performed by the Control Laboratory, Transfusion Service of the Swiss Red Cross, Wankdorfstrasse 10, CH-3014 Berne.Supported by the Swiss National Science Foundation.     

Investigations on unknown ninhydrin-reacting substances in human blood serum. I. Attempts at identification of three such substances

Zusammenfassung Mittels Dünnschicht- und Papier-chromatographie wurden die ninhydrinpositiven Substanzen im Blutserum gesunder Versuchspersonen untersucht, wobei 26 freie Aminosäuren und 5 andere ninhydrinpositive Substanzen festgestellt wurden, wovon 3 neue Peptide sind.     

Erythrocyte catechol-0-methyltransferase and plasma dopamine-beta-hydroxylase in human umbilical cord blood

Plasma dopamine-beta-hydroxylase enzymatic activity and immunoreactive protein levels in human umbilical cord blood are only about 2% as great as values in the blood of older subjects. Erythrocyte catechol-0-methyltransferase activity levels in umbilical cord blood are very similar to those in the blood of adult subjects.     

Developmental homeostasis and heterozygosity for blood group loci in a human population

Summary Relationship between the variability of 5 independent morphological characters and the heterozygosity level at 4 blood group loci were determined in Israel. An increase in the heterozygosity level led to a reduction of the range and coefficient of variation of the morphological traits and also led to an increase of modal phenotype frequencies in the group.We are very grateful to Professor B. Arensburg of our department at the Tel Aviv University for his kind permission to use anthropometric data collected by him.     

K-Lymphocyte cytotoxicity: role of human blood group ABO, rhesus and P alloantibodies]

Using human erythrocytes of known antigenic density, sensitized by ABO and Rhesus (D) alloantibodies, it is shown that K cell cytotoxicity mediated by peripheral blood lymphocytes is directly correlated with the number of IgG molecules specifically bound to the target cell surface. The lytic sensitivity of P1k but not P2 or p erythrocytes coated with anti-Tja (anti-P + P1 + Pk) antibodies, demonstrates that effector K cells are mainly triggered through the IgG ANTI-Pk component of such sera.     

The structure of gephyrotoxin (GTX) 223AB

Summary The structure 3-butyl-5-propylindolizidine (2), tentatively assigned to a minor alkaloid in skin extracts from a number of poison frogs of the Neotropical genusDendrobates, has been confirmed and its stereochemistry determined as 5E, 9E (2d) by comparison on GC and GC-MS with the four synthetic diastereomers2a-2d.     

The interaction of protamine with human blood plasma proteins

Zusammenfassung Es wurden Interaktionen von Protamin mit vorher in Agar-Gel elektrophoretisch getrennten plasmatischen Eiweisskörpern untersucht. Neben der schon früher bekannten Interaktion mit Fibrinogen wurden auch solche mit beiden Klassen der plasmatischen Lipoproteine gefunden.     

Lewis blood group activity in Fasciola hepatica]

Lewis blood group specificities are detected in the liver Fluke: Fasciola hepatica. Such specificities had never been reported in nature, other than in the human body. The investigation of this phenomenon might contribute to a better understanding of the mechanisms involved in parasite-host relationship.     

Isolation of blood group A substance fromTubifex rivulorum

Zusammenfassung Es wird über das Vorkommen von Agglutininen und Blutgruppensubstanzen bei Avertebraten berichtet. Besonders interessant sind dabei Agglutinine gegen Neuraminsäure sowie die Verbreitung von Blutgruppensubstanz A.     

Relationships of the soluble human A, B, and H antigens of blood group A1B individuals

Ouchterlony double diffusion reactions with precipitating antibodies and lectins provide visual evidence that in saliva of A1B secretor individuals the A and B antigens are predominantly situated on the same molecule, while the H antigen is on a different molecule.     

Relationships of the soluble human A,B, and H antigens of blood group A1B individuals

Summary Ouchterlony double diffusion reactions with precipitating antibodies and lectins provide visual evidence that in saliva of A₁B secretor individuals the A and B antigens are predominantly situated on the same molecule, while the H antigen is on a different molecule.