共查询到20条相似文献,搜索用时 15 毫秒
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The effect of urinary gonadotropin-inhibiting substances (GIS) on the androgen synthesis in rat testes was studied in vitro and in vivo. GIS, which was added to the incubation medium containing tesased testicular tissues and injected into rats for 2 days, showed a suppressive effect on the formation of androstenedione from pregnenolone in the testis. 相似文献
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Summary The effect of urinary gonadotropin-inhibiting substances (GIS) on the androgen synthesis in rat testes was studied in vitro and in vivo. GIS, which was added to the incubation medium containing teased testicular tissues and injected into rats for 2 days, showed a suppressive effect on the formation of androstenedione from pregnenolone in the testis.Supported by a Scientific Research Grant from the Ministry of Education of Japan. 相似文献
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Summary The follow-up experiments with rats revealed auto-antibodies against spleens damaged by an i.v. ethyl palmitate injection. The antibodies could be shown in some animals only. 相似文献
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Drori Ben-Ishay Ruth Saliternik A. Welner 《Cellular and molecular life sciences : CMLS》1972,28(11):1321-1322
Résumé La réponse au régime Doca-sel (D. S.) a été utilisée comme critère de sélection pour séparer, par croisement consanguin, deux colonies de rats manifestant une susceptibilité bien différente à l'hypertension artérielle. Les résultats obtenus dans la 6ème génération de nos colonies normotensive et hypertensive font l'objet de ce raport. Le rôle des facteurs héréditaires dans la susceptibilité ou la résistance à l'hypertension du type D. S. est démontrée. 相似文献
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M. C. Bosland D. H. G. Versteeg W. de Jong 《Cellular and molecular life sciences : CMLS》1980,36(2):224-224
Summary Local administration of 6-hydroxydopamine in the subarachnoidal space of the spinal cord in rats resulted in a selective long-lasting depletion of spinal noradrenaline, but not of dopamine, and prevented the occurrence of postdecapitation convulsions. 相似文献
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M Castagna J Boy J Chauveau M Flodrops 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1975,280(23):2713-2716
The addition of theophylline to the diet of rats given the carcinogen 4-dimethylaminoazobenzene did not significantly impair the development of hepatomas. In contrast, the feeding of theophylline has been associated to some histopathological changes in bladder membrane leading to the occurrence of malignant papillomas. 相似文献
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The increase of thiobarbituric acid reacting substances in rats with experimental chronic hypoxia 总被引:1,自引:0,他引:1
T. Yoshikawa Y. Furukawa Y. Wakamatsu H. Tanaka S. Takemura M. Kondo 《Cellular and molecular life sciences : CMLS》1982,38(3):312-313
Summary Feeding under conditions of reduced oxygen supply prompted an increase in serum, arterial and brain tissue levels of thiobarbituric acid (TBA)-reacting substances. These observations indicated the possibility that hypoxia might be one of the factors predisposing to the accumulation of lipid peroxide. 相似文献
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Summary Selective warming of the spinal cord with ventral and dorsal roots cut can generate panting in the conscious dog. 相似文献
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A. V. Champakamalini R. Appaswami Rao 《Cellular and molecular life sciences : CMLS》1977,33(4):499-500
Summary The effect of administering barbital sodium, phenobarbitone or butobartitone during pregnancy was investigated in rats. The study shows that these bartiturates affect the litter-size and retard the foetal growth markedly. The embryos produced are significantly undersized.Acknowledgments. The authors wish to express their gratitude to Prof. M. R. Rajasekar Setty for the encouragement received and CSIR, India, for the award of a Research Fellowship to A. V. Champakamalini. 相似文献
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Summary In young spontaneously hypertensive rats (SHR), dopamine -hydroxylase (DBH) and phenylethanolamine N-methyltransferase (PNMT) activities were examined in the brainstem nuclei. Activation of noradrenergic neurons in the locus coeruleus, A2 and spinal intermediolateral cell areas, resulting in enhanced sympathetic nervous activity in the periphery, initiates hypertension. Adrenergic neurons, unchanged in these and A1 cell areas of young SHR, are not involved in the development of hypertension in SHR. 相似文献
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W. Bollag 《Cellular and molecular life sciences : CMLS》1972,28(10):1219-1220
Zusammenfassung Oral verabreichte Vitamin-A-Säure besitzt bei Mäusen eine prophylaktische Wirkung auf die Entstehung von hauptpapillomen und Hautkarzinomen. die mittels lokaler Applikation von Dimethylbenzanthracen und Krotonöl erzeugt wurden. Vitamin-A-Säure verzögert das Auftreten, verlangsamt das Wachstum und führt zur Rückbildung von Papillomen. Ferner wird die Induktion von Karzinomen gehemmt. Diese treten bei prophylaktischer Verabreichung von Vitamin-A-Säure verzögert und in deutlich verringerter Anzahl auf. Der Wirkungsmechanismus wird diskutiert. 相似文献