Eucaryotic codes

This article is a review of the rules used by eucaryotic cells to translate a nuclear messenger RNA into a polypeptide chain. The recent observation that these rules are not identical in two species of a same phylum indicates that they have changed during the course of evolution. Possible scenarios for such changes are presented.     

基于经典Goppa码的非对称量子稳定子码构造

自从Calderbank等人建立了从经典纠错码构造量子纠错码的CRSS构造法以来,人们利用经典纠错码构造了大量的性能良好的量子纠错码,称为量子稳定子码．最近的物理实验表明,大多数量子力学系统中发生量子比特翻转错误的概率远小于量子相位翻转错误的概率,针对这一情况所构造的纠错码称为非对称量子纠错码．本文分别基于嵌套包含Goppa码与对偶包含Goppa码构造了一系列新的非对称量子稳定子码．在基于嵌套包含Goppa码构造非对称量子码时,首先对Goppa码的选取做一定的限制．以便解析构造量子码．对于一般情况下的构造,则是借助于数学软件Matlab计算Goppa码对偶码的最小距离进行的．在基于对偶包含Goppa码的构造中,所构造量子码的纠错能力主要体现在纠正Z类型错误上．     

Synthetic genes for the elucidation of glycosylation codes for arabinogalactan-proteins and other hydroxyproline-rich glycoproteins

Hydroxyproline-rich glycoproteins (HRGPs) are ubiquitous architectural components of the growing plant cell wall, accounting for as much as 10-20% of the dry weight. HRGPs are implicated in all aspects of plant growth and development, including responses to stress. The HRGP superfamily contains three major groups which represent a continuum of peptide periodicity and hydroxyproline-O-glycosylation. These groups range from the highly periodic and lightly arabinosylated repetitive proline-rich proteins (PRPs), through the crosslinked extensins which are periodic and highly arabinosylated, to the arabinogalactan-proteins (AGPs) which are the most highly glycosylated and least periodic. The repetitive units are small, often only four- to six-residue-glycosylated modules viewed hypothetically as functional motifs, or glycomodules. The Hyp contiguity hypothesis predicts that Hyp arabinosylation increases with Hyp contiguity and that clustered noncontiguous Hyp residues are sites of arabinogalactan polysaccharide addition in the AGPs and gums. Recent results involving glycosylation site mapping of endogenous HRGPs and HRGP design using synthetic genes have corroborated the hypothesis. The uses of synthetic genes in HRGP glycosylation site mapping and structural/functional analysis are also discussed.