Isoforms of baker's yeast transketolase

. .     

The tonically acting pulmonary receptors innervated by C fibres

. , , , , . (, ) . . .     

G-band patterns as chromosomal markers,and the interpretation of chromosomal evolution in wild sheep (Ovis)

- . Ovis musimon (2n=54) O. orientalis (2n=54) - - -O. canadensis mexicana (2n=54) O. musimon x O. canadensis ₁₂ - . ₂ 27 . - .

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Supported by National Science Foundation Grant no. GB 32114X and the Sprague Foundation. We thank Dr. T. C. Hsu for assistance in making the chromosome preparations and for advice and encouragement. The Trustees of the Rachelwood Wildlife Research Preserve generously allowed the biopsy of specimens of their custody. Mr.Arthur Popham kindly provided the specimens from Iran while Dr.R. M. Robinson obtained biopsies from the desert sheep.     

The effect of chloramphenicol analogs on protein biosynthesis in a cell-freeEscherichia coli B system

a aaa a aa aa a a E. coli aa, a aa aa a , a a aa - a .

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Laboratory of Biological Investigations.

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Laboratory for Chemistry of Antibiotics.     

Protein biosynthesis and hyperpolarization of cells

.     

Normalization by nucleotides of impairments in deamination of nitrogenous compounds in liver of tumor-bearing mice

-2 (3)--3- - .     

Some functional characteristics of the electroreceptors (the ampullae of lorenzini) of elasmobranchs

. . , ( I) , ( )- .     

Extrapyramidal pathways with monosynaptic effects upon primate α-motoneurons

, , , , , -.     

A new synthetic method of coumestan derivatives

Zusammenfassung Die Synthese von 7-Hydroxy-5,6-dimethoxybenzofurano[3,2:3,4]coumarin aus 7,2-Dihydroxy-oder 7-Benzyloxy-2-hydroxy-4,5-dimethoxyisoflavon wird beschrieben.     

Changes in mouse liver superoxide dismutase activity and lipid peroxidation during embryonic and postpartum development

Summary In inbred mice possessing high and low tissue superoxide dismutase (SOD) activity, it was observed that the difference in the SOD activities of the liver homogenates during development attains the maximum characteristic of the strain by about the 150th day. Subsequently, the SOD activity change displays a tendency in contrast with the age and the basic state. In the course of the development, a difference was also observed between the 2 mouse strains in the lipid peroxidation variation.Part XVIII of the series Properties of enzymes.     

The stimulating action of gastrin pentapeptide,histamine and cyclic adenosine 3′,5′-monophosphate on carbonic anhydrase in rat stomach

, 3,5- . , , , , 3,5-.

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With the technical assistance ofYu. M. Konstantinov andT. V. Zymonina.     

Chromosomes and some issues of the evolution of the ground squirrel genusCitellus (Rodentia: Sciuridae)

Citellus (s. str.) relictus, C. dauricus C. pygmaeus (2=36, NF=72). . (Colobotis) erythrogenys . fulvus -. . (Urocitellus) undulatus (2n=32, NF=64) . columbianus. Citellus, , Citellus, . , .     

A study of the mechanism of polymyxin M inactivation

.I.NH₄OH , N N - - ,-. , .     

Separation of rat liver mitochondrial amine oxidases

.     

Exchange of tritium from randomly tritiated taurocholate by microbial bile salt oxidoreductases

Summary Tritium distribution on randomly labelled taurocholate (TC) was estimated at 28%, 4%, 1% and <0.5% on the hydrogens opposite the 3-, 7- and 12-OH groups and taurine moiety respectively. Anomalously,C. perfringens 3-hydroxysteroid dehydrogenase (3-HSDH) catalyzed tritium loss of 36% on formation of 7-, 12-dihydroxy-3-keto-5-cholanoate, implying additional losses of tritium at other sites by this enzyme.This work is supported by the National Cancer Institute.     

Interaction of 1-anilino-8-naphthalene sulfonate with yeast glyceraldehyde-3-phosphate dehydrogenase

1--8- () -3- () . []:[]<10:1 140 000 3±1 5×10^–5 . , i 5×10^–5 –6×10^–5 M. , .     

Induced seed protein mutant of barley

. 51%. () 29% 9% - . .

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Seed samples may be obtained upon application toH. Doll.     

A historical review of the problem of mitogenetic radiation

Summary The miracle of caryokinesis was the starting point that stimulated Alexander G. Gurwitsch to carry out his famous mitogenetic experiments in 1923. The results obtained confirmed his hypothesis of a weak radiation from cells, which is able to trigger the growth of other cells. Extensive experimental work within the first two decades after this discovery indicated that the problem of mitogenetic radiations is generally related to the biological significance of UV-radiation. Both energetic and informational aspects have to be considered, namely radiation effective in activating molecules, and that involved in arranging them into larger units.The molecular organization of biological structures is evidently governed by nonequilibrium conditions needing the uptake or emission of radiation. These concepts of A. G. Gurwitsch can be linked with modern approaches based on hypotheses of coherence in biology, synergetics and dissipative structures. However, the question of causal interrelationships between this part of non-equilibrium radiation and biological matter on different levels of evolution has to be solved now.     

The role of repair in radiobiology

Summary Apart from cancer and mutation induction, radiobiological effects on mammals are mostly attributable to cell death, defined as loss of proliferative capacity. Survival curves relate retention of that capacity to radiation dose, and often manifest a quasi-threshold (shoulder). The shoulder is attributable to an initial mechanism of repair (Q-repair) which is gradually depleted as dose increases. Another form of repair, which is not depleted (P-repair), increases the dose required to deliver an average of one lethal event per cell (dose D₀). Neither form of repair can unambiguously be linked with repair of defects in isolated DNA. An important initial lesion may well be disruption of the complex structural relationship between the DNA, nuclear membrane and associated proteins. One form of P-repair may be restoration of that structural relationship.     

Distribution of C19-steroid conjugates in plasma protein fractions

Zusammenfassung Nach. i.v. Gabe von 7-³H-Dehydroepiandrosteron wurde menschliches Plasma einer präparativen Zonenelektrophorese unterworfen und in Albumine, ₁-, ₂-,- und-Globuline zerlegt. Aus den einzelnen Proteinfraktionen trennte man freie Steroide, Steroid-Sulfokonjugate und -Glukuronoside ab und untersuchte letztere Fraktionen auf ihren Gehalt an markierten C₁₉-Steroiden. Es zeigte sich, dass die Steroid-Sulfokonjugate vornehmlich in der Proteinfraktion der Albumine, die Steroid-Glukuronoside dagegen bevorzugt in der Proteinfraktion der ₁-Globuline auftraten.